Results 21 to 30 of about 309,711 (266)

Generation of Soluble Interleukin-11 and Interleukin-6 Receptors: A Crucial Function for Proteases during Inflammation

Mediators of Inflammation, 2016
The cytokines interleukin-11 (IL-11) and IL-6 are important proteins with well-defined pro- and anti-inflammatory functions. They activate intracellular signaling cascades through a homodimer of the ubiquitously expressed signal-transducing β-receptor ...
Juliane Lokau, Maria Agthe, Christoph Garbers   +2 more
doaj   +1 more source

Circulating endothelial progenitor cells and inflammatory markers in type 1 diabetes after an acute session of aerobic exercise [PDF]

Archives of Endocrinology and Metabolism
Objective: To determine circulating endothelial progenitor cells (EPC) counts and levels of inflammatory markers in individuals with and without type 1 diabetes mellitus (T1DM) in response to an intense aerobic exercise session. Subjects and methods: In
Patrícia Martins Bock, Raíssa Borges Monteiro, Clara Krummenauer Maraschin, Ana Paula Alegretti, Mariela Granero Farias, Fabiane Spagnol, Patricia Luciana da Costa Lopez, Lucas Porto Santos, Lucas Helal, Ruy Silveira Moraes, Daniel Umpierre, Beatriz D. Schaan   +11 more
doaj   +1 more source

The Impact of CB1 Receptor on Inflammation in Skeletal Muscle Cells

Journal of Inflammation Research, 2021
Mansour Haddad Faculty of Pharmacy, Philadelphia University, Amman, JordanCorrespondence: Mansour Haddad Email Dr.man.haddad@gmail.comBackground: Various factors trigger the inflammatory response and cytokine activation in skeletal muscle.
Haddad M
doaj  

Autoinflammatory disease: clinical perspectives and therapeutic strategies

Inflammation and Regeneration, 2022
The molecular platforms of the innate immune system are essential to recognize pathologic external factors that are crucial to differentiate these danger signals from host motifs.
Atsushi Kawakami, Endo Yushiro, Koga Tomohiro, Yoshiura Koh-ichiro, Migita Kiyoshi   +4 more
doaj   +1 more source

Adenosine-dependent regulation of paracrine factors expression in human venous blood monocytes

Бюллетень сибирской медицины, 2011
The flow cytometry analysis of human peripheral blood monocytes separated by a two step density gradient centrifugation is reported. The expression of mRNA level of adenosine receptor (AdoR) subtypes (A1, A2A, A2B and A3) and interleukin 6 (IL-6 ...
S. V. Ryzhov, K. S. Yuryeva, K. V. Goremykin, Ye. V. Korotkaya, I. V. Saltykova, Yu. A. Yakovleva, Ye. S. Kulikov, O. S. Fyodorova, Ye. E. Kremer, N. S. Fattakhov, A. E. Sazonov   +10 more
doaj   +1 more source

Temporal and tissue-specific requirements for T-lymphocyte IL-6 signalling in obesity-associated inflammation and insulin resistance

Nature Communications, 2017
Interleukin-6 (IL-6) is increased in obesity and activates T cells to promote inflammation. Here, Xuet al. use mice that lack IL-6 receptors on T cells to uncover the temporal and tissue-specific effects of classic and trans IL-6 signalling on ...
Elaine Xu, Mafalda M. A. Pereira, Ismene Karakasilioti, Sebastian Theurich, Mona Al-Maarri, Gunter Rappl, Ari Waisman, F. Thomas Wunderlich, Jens C. Brüning   +8 more
doaj   +1 more source

The Effects of Pro-Inflammatory Cytokines on Human Body and Their Relation with Diseases (Review Article)

Academic Science Journal, 2023
Cytokines are important mediators in inflammatory disorders that affect the entire body. Signaling molecules called pro-inflammatory cytokines, also known as inflammatory cytokines, are released by the immune system cells including macrophages and T ...
Khalid Shaalan Sahab , Mohammed Asaad Mahdi, Ammar M. K. AL-Azzawi   +2 more
doaj   +1 more source

Role of Soluble Interleukin-6 Receptor With Interleukin-6 in Human Hematopoiesis

Hematology, 1997
A complex of soluble interleukin-6 receptor (sIL-6R) and interleukin-6 has been shown to play some roles in human hematopoiesis. It activates gp130 signal to stimulate human erythroid, megakaryocytic and primitive hematopoietic progenitor cells, which express gp130 but not IL-6R, in the presence of c-Kit signal mediated by stem cell factor (SCF).
K, Tsuji, T, Nakahata
openaire   +2 more sources

Soluble interleukin‐6 receptor in young adults and its relationship with body composition and autonomic nervous system

Physiological Reports, 2019
Background The immune system generates inflammatory responses through cytokines like Interleukin 6 (IL‐6) and the Tumor Necrosis Factor alpha (TNF α); these cytokines mediate cellular responses aided by the presence of soluble receptors such as: Soluble ...
Henry H. León‐Ariza, Daniel A. Botero‐Rosas, Edward J. Acero‐Mondragón, Dario Reyes‐Cruz   +3 more
doaj   +1 more source

Contribution of Extracellular Signal-Regulated Kinase to UTP-Induced Interleukin-6 Biosynthesis in HaCaT Keratinocytes

Journal of Pharmacological Sciences, 2006
UTP causes interleukin (IL)-6 production via mRNA expression through P2Y2/P2Y4 receptors in human HaCaT keratinocytes. In the present study, we analyzed the mechanism of UTP-induced IL-6 production in these cells.
Daisaku Kobayashi, Satoko Ohkubo, Norimichi Nakahata   +2 more
doaj   +1 more source