Results 181 to 190 of about 94,523 (291)

Buccal Mucosa as Substrate for Direct Immunofluorescence Should Be Included Early in the Diagnostic Work Up of Ocular Mucous Membrane Pemphigoid

JEADV Clinical Practice, EarlyView.
ABSTRACT Background In ocular mucous membrane pemphigoid (MMP) direct immunofluorescence (DIF) represents the gold standard for definitive diagnosis. However, up to 50% of ocular MMP cases do not meet the immunopathological criteria. In addition, the risk of exacerbating conjunctival cicatrization makes ocular biopsy technically difficult to obtain ...
Andrea Gabusi, Michelangelo La Placa, Davide Bartolomeo Gissi, Federica Filippi, Camilla Loi, Cosimo Misciali, Federico Bardazzi   +6 more
wiley   +1 more source

Regulation of neutrophil function by the extracellular matrix. [PDF]

Biochem Soc Trans
Calo CJ, Radke M, Patil T, Hind LE.
europepmc   +1 more source

Mouse Vocal Fold Permeability In Vivo: Effects of Novel Low‐Tech Injury and Instillation Methods

The Laryngoscope, EarlyView.
Improving experimental mouse vocal fold injury and instillation approaches is necessary to advance preclinical models of laryngeal disease. We have successfully repurposed low‐tech, quick, and reliable injury and instillation methods established in respiratory research. Using these methods, we show that murine vocal fold epithelium is inherently highly
Renee E. King, Ella T. Ward‐Shaw, Paul F. Lambert   +2 more
wiley   +1 more source

Immunohistochemical Expression of Laminin 332 in Triple-Negative Breast Carcinoma: A Cross-Sectional Study. [PDF]

Cureus
Kannappalli K, Raju K, Kamisetty KP.
europepmc   +1 more source

Single‐Cell Transcriptomic Analysis Reveals Epithelial‐Mesenchymal Transition and Key Gene AGRN as a Universal Programme in Gastrointestinal Tumours by an Artificial Intelligence‐Derived Prognostic Index

Med Research, EarlyView.
Intra‐tumour heterogeneity is present in gastrointestinal tumours at the single‐cell level. Cell cycling, EMT, MYC and TNF‐α are the four main consensus meta‐programs in gastrointestinal tumours. Then, a prognostic model based on intratumoral heterogeneity was constructed using an artificial intelligence‐derived prognostic index.
Zhizhan Ni, Pengyuan Zhu, Liming Liu, Haiyang Wang, Jinzhe Zhou, Xianqing Wang, Song Wang, Liangchen Zhu, Songze Zhang, Yongxin Zhou, Bujun Ge, Qi Huang, Chenshen Huang   +12 more
wiley   +1 more source

Extracellular matrices regulate extravasation journey of leukocytes and inflammatory tissue fate. [PDF]

Elife
Li YT.
europepmc   +1 more source

Tumor Organoids: Breakthroughs in Clinical Decision Making, Drug Development, and Translational Advances Beyond Conventional Models

Med Research, EarlyView.
ABSTRACT Tumor organoid models are revolutionizing cancer research by bridging the translational gap between conventional two‐dimensional cell cultures and animal models. This Editorial thoroughly explores the fundamental innovations of patient‐derived organoid technology.
Yimao Wu, Ruowei Sun, Gokhan Zengin, Shuai Ren, Meng‐Yao Li   +4 more
wiley   +1 more source

Invasin-functionalized PIC hydrogels enable long-term 3D culture of epithelial organoids. [PDF]

Proc Natl Acad Sci U S A
Wijnakker JJAPM, Lim S, Schreurs R, Faria JF, Korving J, Begthel H, Iyer KK, Kouwer PHJ, Clevers H.   +8 more
europepmc   +1 more source

Uncoupling TGFβ1 signalling from collagen protein synthesis in Dupuytren's disease

The Journal of Pathology, EarlyView.
Abstract Dupuytren's disease is a fibroproliferative disorder of the palmer fascia (PF) characterised by flexion contractures in the hand. Dupuytren's disease can be treated surgically, but disease recurrence rates are high, potentially due to continual production of matrisomal proteins.
Gabriella Cooper, Jade A Gumbs, Sahem Alkharabsheh, Katie J Lee, Alan Carter, Hannah Coleman, Niamh S O'Heneghan‐Yates, Rama Ijaz, Emma Beamish, Lisa A Menezes, Triantafillos Liloglou, Peter D Clegg, Elizabeth G. Canty‐Laird   +12 more
wiley   +1 more source

The meningeal-cerebellar axis: a new perspective on cerebellar development. [PDF]

Cell Mol Life Sci
Al-Sayyar A, Salvon L, Haidar N, Schult P, Kassem O, Rua R, Romano A.   +6 more
europepmc   +1 more source