Results 201 to 210 of about 94,523 (291)

Aggressive Glioblastoma Cells Enhance the Migratory Persistence and Velocity of Less Aggressive Cells to Promote Tumor Dissemination

open access: yesSmall, EarlyView.
We identify biophysical motility parameters explaining how less aggressive EGFRwt‐overexpressing Glioblastoma cells become more infiltrative when influenced by aggressive EGFRvIII‐expressing cells. Using bulk assays and microfluidic chips, we show that EGFRvIII cells enhance velocity and persistence in EGFRwt cells via Src‐mediated communication ...
Fatima‐ezzahra Ait Mohand   +5 more
wiley   +1 more source

Renovating Neural Networks With Viral‐Mediated Gene Transfer From A Tissue Contacting Matrix Mimic

open access: yesSmall, EarlyView.
Fmoc‐DDIKVAV self‐assembling peptidemediated delivery of AAV‐BDNF significantly enhances neuroprotection in the striatum of a mouse model compared with AAV‐BDNF injection alone. This synergistic integration of biomaterial scaffolding and gene therapy holds substantial promise for slowing the progression of neurodegenerative diseases such as Huntington ...
Shiva Soltani Dehnavi   +11 more
wiley   +1 more source

ChitoSilkBioPatch: A bio‐inspired wound dressing scaffold for antibiotic‐free diabetic wound management

open access: yesVIEW, EarlyView.
We present ChitoSilkBioPatch, a maleimide‐functionalized chitosan/dACM hydrogel integrated with a stretchable nanopatterned silk mesh to provide intrinsic, antibiotic‐free antibacterial activity and bioactive wound support. The scaffold eliminates S. aureus and P.
Dorsa Dehghan‐Baniani   +12 more
wiley   +1 more source

Optimization of Methods for the Quantitative Analysis of Global Cell Surface Proteome and Cell Surface Polarization. [PDF]

open access: yesInt J Mol Sci
Kuffa K   +6 more
europepmc   +1 more source

Mechanism of Ammonia‐Induced Brain Damage in Chinese Striped‐Necked Turtle (Mauremys sinensis)

open access: yesIntegrative Zoology, EarlyView.
High levels of ammonia disrupt the integrity of the brain barrier in Mauremys sinensis, leading to tissue edema. This, in turn, triggers a series of cascade reactions, including disturbances in neurotransmitter levels, particularly glutamate, which might further exacerbate the neurotoxic effects.
Yunjuan Xiao   +6 more
wiley   +1 more source

Modified cytoskeletal and extracellular matrix composition in the canine testis after long‐acting gonadotropin‐releasing hormone agonist deslorelin treatment

open access: yesAndrology, EarlyView.
Abstract Background Long‐acting gonadotropin‐releasing hormone (GnRH) agonists are commonly used for fertility control in male dogs. Their effect on testicular histomorphology has not been clarified. Objectives To elucidate the mechanisms underlying androgen withdrawal in response to long‐acting GnRH agonist deslorelin 4.7 mg treatment on testicular ...
Aykut Gram   +5 more
wiley   +1 more source

Tenascin-C from the tissue microenvironment promotes muscle stem cell maintenance and function through Annexin A2. [PDF]

open access: yesCommun Biol
Cecchini A   +14 more
europepmc   +1 more source

The sensory penis: A comprehensive immunohistological and ontogenetic exploration of human penile innervation

open access: yesAndrology, EarlyView.
Abstract Background Penile sexual sensation relies on intricate neural structures that remain incompletely characterized. Immunohistological insights into their development and organization can enhance understanding of penile neuroanatomy and function, while optimizing surgical outcomes.
Alfonso Cepeda‐Emiliani   +6 more
wiley   +1 more source

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