Results 231 to 240 of about 94,523 (291)

The tympanic covering layer contributes to basilar membrane elasticity potentially influencing human frequency resolution and speech perception

Journal of Anatomy, EarlyView.
In this study we show for the first time that the human basilar membrane contains elastin produced by the so‐called tympanic covering layer. It is believed to play an important functional role in human cochlear tuning, particularly low frequencies linked to our remarkable speech and music perception.
Wei Liu, Claudia Steinacher, Alexander Glueckert, Rudolf Glueckert, Hao Li, Karin Staxäng, Anneliese Schrott‐Fischer, Hanif M. Ladak, Sumit Agrawal, Helge Rask‐Andersen   +9 more
wiley   +1 more source

Organ fibrosis: beyond collagen I expression. Fibroblast phenotype and basement membrane proteins. [PDF]

Am J Physiol Cell Physiol
Biggs RM, Bradshaw AD.
europepmc   +1 more source

Diagnostic Agreement in Subepidermal Blistering Diseases: Is ELISA Test Reliable as Direct Immunofluorescence? A Systematic Review, Meta‐Analysis, and Trial Sequential Analysis

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Objectives Direct immunofluorescence (DIF) is the gold standard for diagnosing subepidermal blistering diseases (SBDs). However, DIF requires specialized expertise; therefore, alternative immunological methods such as enzyme‐linked immunosorbent assays (ELISA) are worth exploring. The aim of this review was to evaluate the diagnostic agreement
Romeo Patini, Gioele Gioco, Michele Davide Mignogna, Stefania Leuci, Francesco Scilla, Davide Gentile, Cosimo Rupe, Enrico Russo, Anna Schiavelli, Carlo Lajolo   +9 more
wiley   +1 more source

Comprehensive analysis based on spatial domains identifies CD44 as a potential target of puerarin. [PDF]

J Cancer Res Clin Oncol
Xi SY, Zhang H, Wang QJ, Liu YJ, Chang SC, Shi CF, Fang D, Tao LH, Cheng HB, Zou X.   +9 more
europepmc   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth, Zhou Yuxi, Yong Jiawen, Wang Lei, Ruf Sabine, Meyle Joerg   +5 more
wiley   +1 more source

NK cell activity in the tumor microenvironment. [PDF]

Front Cell Dev Biol
Kuznetsova AV, Glukhova XA, Beletsky IP, Ivanov AA.   +3 more
europepmc   +1 more source

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

Laminin N-terminus α31 regulates corneal epithelial cell adhesion and migration through modifying the organization and proteolytic processing of laminin 332. [PDF]

PLoS One
Troughton LD, Iorio V, Shaw L, Sugden CJ, Chavda ND, Wilson P, Simoens D, Conway AE, Sala S, Kaja S, Yamamoto K, Hamill KJ.   +11 more
europepmc   +1 more source

Autoimmunity and Periodontitis

Journal of Periodontal Research, EarlyView.
In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga, Vivek Thumbigere‐Math, Mark C. Herzberg   +2 more
wiley   +1 more source

An overview of mechanical microenvironment and mechanotransduction in intervertebral disc degeneration. [PDF]

Exp Mol Med
Ke W, Xu H, Zhang C, Liao Z, Liang H, Tong B, Yuan F, Wang K, Hua W, Wang B, Yang C.   +10 more
europepmc   +1 more source