Results 261 to 270 of about 94,523 (291)
Some of the next articles are maybe not open access.
Trends in Neurosciences, 1989
The ability of the extracellular matrix protein laminin to regulate the survival and differentiation of neurons has led to the search for a neuronal laminin receptor. This article reviews the evidence for the existence of laminin receptors, and then goes on to discuss the difficulties in making the jump from a pharmacological demonstration of the ...
openaire +2 more sources
The ability of the extracellular matrix protein laminin to regulate the survival and differentiation of neurons has led to the search for a neuronal laminin receptor. This article reviews the evidence for the existence of laminin receptors, and then goes on to discuss the difficulties in making the jump from a pharmacological demonstration of the ...
openaire +2 more sources
Laminins and their receptors in the CNS
Biological Reviews, 2018ABSTRACTLaminin, an extracellular matrix protein, is widely expressed in the central nervous system (CNS). By interacting with integrin and non‐integrin receptors, laminin exerts a large variety of important functions in the CNS in both physiological and pathological conditions.
Abhijit Nirwane, Yao Yao
openaire +2 more sources
The 67 kDa laminin receptor increases tumor aggressiveness by remodeling laminin-1
Endocrine Related Cancer, 2005The association between expression of the 67 kDa laminin receptor (67LR) and tumor aggressiveness has been convincingly demonstrated although the exact function of this molecule in the metastatic process has remained unclear. In this study, we tested whether the laminin-1, upon interaction with 67LR, promotes tumor cell aggressiveness; the ...
A. Balsari +8 more
openaire +3 more sources
Receptors for laminin on mammalian cells
The FASEB Journal, 1991Early in development, cells produce an extracellular matrix that provides important cues that regulate gene expression, cell division, and morphogenesis. Interactions with the extracellular matrix are mediated by cell‐surface receptors providing a transmembrane link between extracellular and intracellular compartments.
openaire +2 more sources
Isolation of a tumor cell laminin receptor
Biochemical and Biophysical Research Communications, 1983BL6 murine melanoma cells contain approximately 110,000 cell surface binding sites for the basement membrane glycoprotein laminin. Treatment of isolated melanoma cell plasma membranes with detergent yields a single class of laminin receptor. The receptor was purified 900 fold by laminin affinity chromatography.
N C, Rao +3 more
openaire +2 more sources
Laminin receptors: achieving specificity through cooperation
Trends in Cell Biology, 1995The laminins are a large family of extracellular matrix proteins that can profoundly influence development, differentiation and disease progression. The biological effects of the laminins are mediated by surface receptors that link laminin matrices to intracellular signalling pathways.
openaire +3 more sources
Receptors for laminins during epithelial morphogenesis
Current Opinion in Cell Biology, 1996Laminin-1 is expressed by many embryonic epithelial cell types. It binds to receptors on the epithelial cell surface. The integrin alpha6beta1 is a well known laminin-1 receptor that is expressed on many embryonic epithelial cells. More recently, dystroglycan was discovered as a high-affinity receptor for laminin-1 and laminin-2.
openaire +2 more sources
Integrin Laminin Receptors and Breast Carcinoma Progression
Journal of Mammary Gland Biology and Neoplasia, 2001This review explores the mechanistic basis of breast carcinoma progression by focusing on the contribution of integrins. Integrins are essential for progression not only for their ability to mediate physical interactions with extracellular matrices but also for their ability to regulate signaling pathways that control actin dynamics and cell movement ...
Mercurio, Arthur M. +6 more
openaire +3 more sources
Human neutrophil laminin receptors: activation-dependent receptor expression.
The Journal of Immunology, 1987Abstract Activated human polymorphonuclear leukocytes (PMN) isolated from peripheral blood specifically bind 125I-laminin after stimulation with phorbol 12-myristate 13-acetate (PMA) or f-Met-Leu-Phe (FMLP) at 37 degrees C. Changes in laminin receptor expression are stimulus dose dependent at both chemotactic (10(-10) M to 10(-6) M ...
P S, Yoon +4 more
openaire +2 more sources
[The elastin-laminin receptor].
Journal de la Societe de biologie, 2002Elastin is a major component of the extracellular matrix. Elastin peptides derived from its degradation are present in human sera. Elastin peptides induce on fibroblasts, phagocytic cells, lymphocytes, smooth muscle cells and endothelial cells, a variety of biological effects mediated by the elastin-laminin receptor which has been demonstrated to be ...
T, Fülöp +6 more
openaire +1 more source