Results 31 to 40 of about 94,523 (291)
Ultrastructure of acetylcholine receptor aggregates parallels mechanisms of aggregation
BMC Neuroscience, 2001 Background Acetylcholine receptors become aggregated at the developing neuromuscular synapse shortly after contact by a motorneuron in one of the earliest manifestations of synaptic development. While a major physiological signal for receptor aggregation
Lee Lara K +2 more
doaj +1 more source
The impact of genetic manipulation of laminin and integrins at the blood–brain barrier
Fluids and Barriers of the CNS, 2022 Blood vessels in the central nervous system (CNS) are unique in having high electrical resistance and low permeability, which creates a selective barrier protecting sensitive neural cells within the CNS from potentially harmful components in the blood ...
Sebok K. Halder +2 more
doaj +1 more source
Myelination: all about Rac n roll. [PDF]
, 2007 During the development of the peripheral nervous system, Schwann cells select individual axons from a nerve bundle and establish a one-to-one relationship through a process termed radial sorting. Recent findings identify the Rho family GTPase Rac1 as the
Chan, Jonah
core +2 more sources
The basement membrane protein nidogen-1 supports platelet adhesion and activation
Platelets, 2021 The core structure of the extracellular basement membrane is made up of self-assembling networks of collagen and laminin which associate with each other through the bridging adapter proteins including the sulfated monomeric glycoprotein nidogen.
Hari Hara Sudhan Lakshmanan +12 more
doaj +1 more source
Interactions of the 67 kDa laminin receptor and its precursor with laminin [PDF]
Bioscience Reports, 2009 The 67LR (67 kDa laminin receptor) enables cells to interact with components of the extracellular matrix. The molecule is derived from the 37LRP (37 kDa laminin receptor precursor); however, the precise molecular mechanism of this conversion is unknown. Recombinant 37LRP, expressed in and purified from Escherichia coli, bound to human laminin in a SPR (
Fatehullah, Aliya +6 more
openaire +5 more sources
Deciphering the Mammary Stem Cell Niche: A Role for Laminin-Binding Integrins
Stem Cell Reports, 2019 Summary: Integrins, which bind laminin, a major component of the mammary basement membrane, are strongly expressed in basal stem cell-enriched populations, but their role in controlling mammary stem cell function remains unclear.
Mathilde Romagnoli +13 more
doaj +1 more source
beta1 integrin maintains integrity of the embryonic neocortical stem cell niche. [PDF]
PLoS Biology, 2009 During embryogenesis, the neural stem cells (NSC) of the developing cerebral cortex are located in the ventricular zone (VZ) lining the cerebral ventricles.
Karine Loulier +14 more
doaj +1 more source
Non-integrin laminin receptors in epithelia
Tissue and Cell, 2019 The interactions between cells and the extracellular matrix (ECM) play a major role in normal and pathological conditions. The ECM can modulate several biological functions including cell proliferation, adhesion, differentiation and survival through its interactions with cell receptors.
Gabriel Cloutier +2 more
openaire +2 more sources
Tissue engineering a fetal membrane [PDF]
, 2011 The aim of this study was to construct an artificial fetal membrane (FM) by combination of human amniotic epithelial stem cells (hAESCs) and a mechanically enhanced collagen scaffold containing encapsulated human amniotic stromal fibroblasts (hASFs ...
Adam M. Squires +11 more
core +1 more source
Interaction between the 67 kilodalton metastasis-associated laminin receptor and laminin
Kidney International, 1993 Normal and neoplastic cells interact with laminin via a variety of cell surface proteins. The specific binding sites on laminin for each particular cell surface laminin-binding protein have not yet been identified. In this study, the interaction between laminin and the high affinity metastasis-associated 67 kD laminin receptor (67 LR) was investigated ...
Cioce, V. +3 more
openaire +2 more sources