Results 231 to 240 of about 77,479 (303)

Effectiveness and Safety of Setmelanotide in a Patient With a Heterozygous PCSK1 Deficiency

Obesity, EarlyView.
ABSTRACT Setmelanotide, a melanocortin 4 receptor (MC4R) agonist, is a promising pharmacological treatment option for people with rare monogenic obesity conditions affecting the leptin‐melanocortin signaling pathway, including proprotein convertase subtilisin/kexin type 1 (PCSK1) gene mutations.
Ellina Lytvyak, Arshdeep Rattol, Eduardo Grunvald   +2 more
wiley   +1 more source

Advanced therapy in familial hypercholesterolemia. [PDF]

Can Fam Physician
Gao E, Brunham LR, Goldman RD.
europepmc   +1 more source

Musculoskeletal Outcomes of Glucagon‐Like Peptide‐1 Receptor Agonists Versus Other Antiobesity Agents in Nondiabetic Adults

Obesity, EarlyView.
ABSTRACT Objective This study aimed to evaluate the association of glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) with risks of osteoporosis, major osteoporotic fractures, and degenerative musculoskeletal disorders in nondiabetic adults with obesity compared with other obesity medications.
Jie‐Syuan Wu, Lee‐Yuan Lin, Jia‐Wei Sun, Wei‐Ting Yu, Fara Silvia Yuliani, Shyh‐Hsiang Lin   +5 more
wiley   +1 more source

Six‐ and Twelve‐Month Changes in Body Composition and 24‐h Energy Expenditure After a Very Low‐Calorie Ketogenic Diet

Obesity, EarlyView.
ABSTRACT Objective This study assessed changes in body composition and 24‐h energy metabolism at 6 and 12 months after initiation of a 1‐month very low‐calorie ketogenic diet (VLCKD) in women with obesity. Methods Seventeen women with obesity who completed a 1‐month VLCKD underwent a 4‐week transition phase with carbohydrate reintroduction, followed by
Alessio Basolo, Paolo Piaggi, Valentina Angeli, Paola Fierabracci, Chiara Bologna, Giordano Paolucci, Guido Salvetti, Luca Chiovato, Jonathan Krakoff, Alberto Landi, Ferruccio Santini   +10 more
wiley   +1 more source

Lipidome remodeling in primary biliary cholangitis. [PDF]

Lipids Health Dis
Rogalska M, Rogalski P, Andrzejuk A, Błachnio-Zabielska A, Zabielski P, Flisiak R.   +5 more
europepmc   +1 more source

Inflammation and lipid-related determinants in coronary atherosclerosis: mechanisms, biomarkers, and therapeutic implications. [PDF]

Front Cardiovasc Med
Zhang F, Liao Q.
europepmc   +1 more source

Long-term LDL cholesterol burden and stroke: mechanistic insights and emerging strategies for personalized lipid management. [PDF]

Front Neurol
Li Z, Ye L, Li J, Wang Y, Yang J.
europepmc   +1 more source

LDL receptor-independent mechanisms of proprotein convertase subtilisin/kexin type 9 in cardiovascular pathophysiology. [PDF]

Front Cardiovasc Med
Su H, Guo X, Li Q, Yuan X, Wu X, Zhao Z, Kan Y, Yang Y, Fu Z, Qi Z, Song G.   +10 more
europepmc   +1 more source

Effectiveness and Safety of Bempedoic Acid in Taiwanese Patients With Hypercholesterolemia: A Pragmatic Phase 4 Study (CLEAR Taiwan Study). [PDF]

J Am Heart Assoc
Hsieh IC, Chen DY, Chu CS, Chang YY, Tzeng BH, Huang TC, Lin HH, Chuang WP, Huang CC, Yeh JK, Chu CY, Ho MY, Huang CY, Chen YW, Yang WC, Lin TH, Wu YW.   +16 more
europepmc   +1 more source