Results 171 to 180 of about 90,104 (295)

Laryngopharyngeal Reflux: The Impact of Obesity

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT This article provides an overview of gastro‐esophageal (GERD) and laryngopharynegal (LPRD) reflux diseases in the context of obesity as a confounding entity. A detailed review of the clinical presentation, pathogenesis, diagnosis, and treatment of laryngopharyngeal reflux disease may be found elsewhere.
Abdul Latif H. Hamdan, Mary J. Hawkshaw, Robert T. Sataloff   +2 more
wiley   +1 more source

Fat balance and serum leptin concentrations in normal, hypothyroid and hyperthyroid rats. [PDF]

, 2001
AM Mistry, BA Evans, E Danforth, G Liverini, HC Freake, HF Escobar-Morreale, J Folch, JD Pullar, JH Oppenheimer, JJ Hwa, JM Friedman, JM Friedman, JN Fain, JN Fain, L Brunner, MA Syed, MJ Breslow, MP Mollica, MQ Robert, NJ Rothwell, P Trayhurn, P Trayhurn, S Iossa, S Iossa, S Iossa, S Iossa, SPJ Brooks, T Masaki   +27 more
core   +1 more source

Harbingers of change: Towards a mechanistic understanding of anticipatory plasticity in animal systems

Functional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Phenotypic plasticity is a strategy by which animals alter behaviour, morphology and/or physiology in response to cues of current conditions to cope with environmental heterogeneity.
Lauren Petrullo, Natalie J. Morris, Chloé Tharin, Ben Dantzer   +3 more
wiley   +1 more source

A Frailty‐Based Plasma Proteomic Signature Capturing Overall Health and Well‐Being in Older Adults

Aging Cell, EarlyView.
We derived a 25‐protein blood‐based frailty signature (proteomic frailty index, pFI) predictive of the cumulative frailty index. The pFI was validated across independent cohorts and was significantly associated with physical, clinical, and cognitive function, as well as incident mortality and dementia, highlighting its potential as a biomarker of ...
Sanish Sathyan, Fangyu Liu, Toshiko Tanaka, Luigi Ferrucci, Emmeline Ayers, B. Gwen Windham, Tina Gao, Erica F. Weiss, Julián Candia, Josef Coresh, Nir Barzilai, Sofiya Milman, Keenan A. Walker, Joe Verghese   +13 more
wiley   +1 more source

Effect of the GLP‐1 receptor agonist exenatide on pro‐inflammatory and metabolic biomarkers in individuals with alcohol use disorder: Post hoc results from a randomized, double‐blinded, placebo‐controlled clinical trial

Alcohol, Clinical and Experimental Research, EarlyView.
This study compared pro‐inflammatory and metabolic biomarker profiles between individuals with alcohol use disorder (AUD) and those without, and evaluated the impact of the GLP‐1 receptor agonist exenatide on these biomarkers in the AUD group. At baseline, individuals with AUD exhibited significantly elevated levels of IL‐6, hsCRP, and FGF‐21, and ...
Malthe E. B. Hviid, Lea A. N. Christoffersen, Mette K. Klausen, Thorsten Brodersen, Ole B. Pedersen, Sisse R. Ostrowski, Margit H. Larsen, Mette Kongstad, Mathias E. Jensen, Tina Vilsbøll, Anders Fink‐Jensen   +10 more
wiley   +1 more source

Kisspeptin as a test of hypothalamic dysfunction in pubertal and reproductive disorders

Andrology, EarlyView.
Abstract The hypothalamic–pituitary–gonadal axis is regulated by the gonadotropin‐releasing hormone pulse generator in the hypothalamus. This is comprised of neurons that secrete kisspeptin in a pulsatile manner to stimulate the release of GnRH, and, in turn, downstream gonadotropins from the pituitary gland, and subsequently sex steroids and ...
Aureliane C. S. Pierret, Aaran H. Patel, Elisabeth Daniels, Alexander N. Comninos, Waljit S. Dhillo, Ali Abbara   +5 more
wiley   +1 more source

Maternal, childhood and adolescent influences on Leydig cell functional capacity and circulating INSL3 concentration in young adults: Importance of childhood infections and body mass index

Andrology, EarlyView.
Abstract Background The constitutive Leydig cell hormone insulin‐like peptide 3 (INSL3) is considered a good estimate of the adult Leydig cell functional capacity and appears to remain relatively consistent throughout adult male life, only gradually declining into old age.
Richard Ivell, Bilal Tulumcu, Waleed Alhujaili, Ravinder Anand‐Ivell   +3 more
wiley   +1 more source

A comparative study on infant growth between assisted reproductive technology pregnancy and natural pregnancy

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Although ART infants are associated with a higher incidence of SGA and other birth outcomes, ART infants exhibit a marked tendency for rapid growth during their first year of life. ART, male infants, later gestational age at birth, SGA, city living, younger perinatal age, taller perinatal height, and heavier pre‐pregnancy weight were all independent ...
Anni Chen, Dongyang Wang, Yuyu Zhang, Qianqian Dai, Weixia Yang, Zixiao Zhou, Xuan Shi, Ziyue Zhou, Zijun Ni, Xun Zhuang   +9 more
wiley   +1 more source

Exploring the Relationship Between Adipocytokines and Endometrial Cancer: Identifying Correlations With Clinico-Pathological Prognostic Factors. [PDF]

Cancer Med
Ray I, Möller-Levet CS, Michael A, Butler-Manuel S, Chatterjee J, Tailor A, Haagsma B, Bagwan I, Meira LB, Ellis PE.   +9 more
europepmc   +1 more source

Metabolic associations of human placental lactogen in pregnancies at high metabolic risk: An observational cohort study

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
This observational study in an ethnically diverse pregnancy cohort examined relationships between human placental lactogen (hPL), maternal metabolism, and fetal outcomes. Findings support a role for hPL in metabolic adaptation to pregnancy and suggest potential utility as a marker of fetal growth. Abstract Introduction Human placental lactogen (hPL) is
Kate Rassie, Simon Alesi, Adriana C. H. Neven, Taitum Mason, Eveline Jona, Stacey J. Ellery, Joanne Enticott, Aya Mousa, Anju E. Joham, David Simmons, Helena Teede, TOBOGM Core Investigator Group   +11 more
wiley   +1 more source