Results 11 to 20 of about 2,401,298 (264)
Leptin suppresses development of GLP-1 inputs to the paraventricular nucleus of the hypothalamus
eLife, 2020 The nucleus of the solitary tract (NTS) is critical for the central integration of signals from visceral organs and contains preproglucagon (PPG) neurons, which express leptin receptors in the mouse and send direct projections to the paraventricular ...
Jessica E Biddinger +3 more
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The Importance of Leptin to Reproduction.
Endocrinology, 2020 A healthy nutritional state is required for all aspects of reproduction and signaled by the adipokine leptin. Leptin acts in a relatively narrow concentration range; too much or too little will compromise fertility.
G. Childs +3 more
semanticscholar +1 more source
Frontiers in Psychiatry, 2019 Depression is a chronic and recurrent disorder, associated with high morbidity and risk of suicide. Leptin was firstly described as an anti-obesity hormone, but several actions of leptin in CNS have been reported.
Rafaela Carneiro Cordeiro +10 more
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PATHOGENETIC MECHANISMS OF LEPTIN RESISTANCE
Российский кардиологический журнал, 2015 Leptin is a regulatory protein from adipokines family, that maintain energy homeostasis of the body and deter obesity development. Impaired transfer of leptin signals to hypothalamus leads to leptin resistance and its adverse complications. Understanding
G. A. Chumakova +4 more
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eLife, 2018 Leptin is critical for energy balance, glucose homeostasis, and for metabolic and neuroendocrine adaptations to starvation. A prevalent model predicts that leptin’s actions are mediated through pro-opiomelanocortin (POMC) neurons that express leptin ...
Alexandre Caron +10 more
semanticscholar +1 more source
The role of leptin resistance in the development of thyroid neoplasia
Mìžnarodnij Endokrinologìčnij Žurnal, 2023 Background. Leptin influences energy metabolism, as it is able to inform the central nervous system about adipose tissue reserves, and is also an important neuroendocrine regulator.
O.S. Miroshnichenko
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Leptin regulates gonadotropins and steroid receptors in the rats ovary
Nutrición Hospitalaria, 2013 The leptin hormone is important to satiety and an important link between the nutritional status and reproductive processes. Owing to the contradictory effects of leptin on the ovary and the failure to clarify the precise mechanism by which leptin affects
Fernanda Silveira Cavalcante +2 more
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Frontiers in Physiology, 2022 Although increasing research focuses on the phenomenon of body weight gain in women after menopause, the complexity of body weight regulation and the array of models used to investigate it has proven to be challenging.
Kaitlin E. Burch +5 more
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Frontiers in Immunology, 2018 Leptin is a cytokine, produced mainly by mature adipocytes, that regulates the central nervous system, mainly to suppress appetite and stimulate energy expenditure.
Natália R. T. Amorim +10 more
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Absence of functional leptin receptor isoforms in the POUND (Lepr(db/lb)) mouse is associated with muscle atrophy and altered myoblast proliferation and differentiation. [PDF]
PLoS ONE, 2013 Leptin receptors are abundant in human skeletal muscle, but the role of leptin in muscle growth, development and aging is not well understood. Here we utilized a novel mouse model lacking all functional leptin receptor isoforms (POUND mouse, Lepr(db/lb))
Phonepasong Arounleut +9 more
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