Results 11 to 20 of about 53,696 (166)

In vivo and ex vivo regulation of visfatin production by leptin in human and murine adipose tissue : role of mitogen-activated protein kinase and phosphatidylinositol 3-kinase signaling pathways [PDF]

, 2009
Visfatin is an adipogenic adipokine with increased levels in obesity, properties common to leptin. Thus, leptin may modulate visfatin production in adipose tissue (AT).
Brown, James, Clifford J. Bailey, Jing Chen, Bee K. Tan, Tan, Bee K., Bailey, C. J. (Clifford J.), Adya, Raghu, Randeva, Harpal S., Vinod Menon, James Brown, Hendrik Lehnert, Menon, Vinod, Raghu Adya, Manjunath Ramanjaneya, Harpal S. Randeva, Ramanjaneya, Manjunath, Chen, Jing, Lehnert, Hendrik   +17 more
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PATHOGENETIC MECHANISMS OF LEPTIN RESISTANCE

Российский кардиологический журнал, 2015
Leptin is a regulatory protein from adipokines family, that maintain energy homeostasis of the body and deter obesity development. Impaired transfer of leptin signals to hypothalamus leads to leptin resistance and its adverse complications. Understanding
G. A. Chumakova, A. V. Ott, N. G. Veselovskaya, O. V. Gritsenko, N. N. Shenkova   +4 more
doaj   +1 more source

Gender dimorphism in skeletal muscle leptin receptors, serum leptin and insulin sensitivity. [PDF]

PLoS ONE, 2008
To determine if there is a gender dimorphism in the expression of leptin receptors (OB-R170, OB-R128 and OB-R98) and the protein suppressor of cytokine signaling 3 (SOCS3) in human skeletal muscle, the protein expression of OB-R, perilipin A, SOCS3 and ...
Borja Guerra, Teresa Fuentes, Safira Delgado-Guerra, Amelia Guadalupe-Grau, Hugo Olmedillas, Alfredo Santana, Jesus Gustavo Ponce-Gonzalez, Cecilia Dorado, José A L Calbet   +8 more
doaj   +1 more source

Identification of a non-mammalian leptin-like gene:characterization and expression in the tiger salamander (Ambystoma tigrinum) [PDF]

, 2006
Leptin is well established as a multifunctional cytokine in mammals. However, little is known about the evolution of the leptin gene in other vertebrates. A recently published set of ESTs from the tiger salamander (Ambystoma tigrinum) contains a sequence
Joseph, N, Joseph, Nerine, Sharp, PJ, Boswell, T, Sharp, Peter J, Burt, DW, Boswell, Timothy, Dunn, Ian C, Wilson, Peter W, Wilson, PW, Burt, David W, Dunn, IC   +11 more
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Leptin regulates gonadotropins and steroid receptors in the rats ovary

Nutrición Hospitalaria, 2013
The leptin hormone is important to satiety and an important link between the nutritional status and reproductive processes. Owing to the contradictory effects of leptin on the ovary and the failure to clarify the precise mechanism by which leptin affects
Fernanda Silveira Cavalcante, Verónica Aiceles, Cristiane da Fonte Ramos   +2 more
doaj   +1 more source

Leptin Elicits LTC4 Synthesis by Eosinophils Mediated by Sequential Two-Step Autocrine Activation of CCR3 and PGD2 Receptors

Frontiers in Immunology, 2018
Leptin is a cytokine, produced mainly by mature adipocytes, that regulates the central nervous system, mainly to suppress appetite and stimulate energy expenditure.
Natália R. T. Amorim, Tatiana Luna-Gomes, Tatiana Luna-Gomes, Marcos Gama-Almeida, Glaucia Souza-Almeida, Claudio Canetti, Bruno L. Diaz, Peter F. Weller, Patricia Torres Bozza, Clarissa M. Maya-Monteiro, Christianne Bandeira-Melo   +10 more
doaj   +1 more source

The role of leptin resistance in the development of thyroid neoplasia

Mìžnarodnij Endokrinologìčnij Žurnal, 2023
Background. Leptin influences energy metabolism, as it is able to inform the central nervous system about adipose tissue reserves, and is also an important neuroendocrine regulator.
O.S. Miroshnichenko
doaj   +1 more source

Leptin fails to blunt the lipopolysaccharide-induced activation of the hypothalamic-pituitary-adrenal axis in rats [PDF]

, 2014
Copyright @ 2013 The authors. This work is licensed under a Creative Commons Attribution 3.0 Unported License.Obesity is a risk factor for sepsis morbidity and mortality, whereas the hypothalamic-pituitary-adrenal (HPA) axis plays a protective role in ...
Bloom, SR, Basharat, S, Parker, JA, Murphy, KG, John, CD, Buckingham, JC   +5 more
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Relationship Between Circulating Metabolic Hormones and Their Central Receptors During Ovariectomy-Induced Weight Gain in Rats

Frontiers in Physiology, 2022
Although increasing research focuses on the phenomenon of body weight gain in women after menopause, the complexity of body weight regulation and the array of models used to investigate it has proven to be challenging.
Kaitlin E. Burch, Kelly McCracken, Daniel J. Buck, Randall L. Davis, Dusti K. Sloan, Kathleen S. Curtis   +5 more
doaj   +1 more source

Obesity and the ageing brain : could leptin play a role in neurodegeneration? [PDF]

, 2011
Obesity and ageing are both characteristics of the human population that are on the increase across the globe. It has long been established that ageing is the major risk factor for neurodegenerative conditions such as Alzheimer’s disease, and it is ...
G. H. Doherty, Doherty, Gayle Helane
core   +1 more source