Results 11 to 20 of about 94,971 (311)
Frontiers in Psychiatry, 2019 Depression is a chronic and recurrent disorder, associated with high morbidity and risk of suicide. Leptin was firstly described as an anti-obesity hormone, but several actions of leptin in CNS have been reported.
Rafaela Carneiro Cordeiro +10 more
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Effects of diabetes family history and exercise training on the expression of adiponectin and leptin and their receptors [PDF]
, 2009 The daughters of patients with diabetes have reduced insulin sensitivity index (ISI) scores compared with women with no family history of diabetes, but their ISI increase more in response to exercise training(1).
Barwell, Nicholas D. +7 more
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Leptin receptor in boar spermatozoa [PDF]
International Journal of Andrology, 2007 SummaryLeptin is active in both metabolism and reproduction. In fact, it seems to exert an inhibitory action on gonadal functions by reducing testosterone production. The presence of leptin in human and boar seminal plasma and in human spermatozoa has been demonstrated; recently, leptin receptors (Ob‐R) have been localized in human spermatozoa, thus ...
DE AMBROGI, MARCO +3 more
openaire +2 more sources
PATHOGENETIC MECHANISMS OF LEPTIN RESISTANCE
Российский кардиологический журнал, 2015 Leptin is a regulatory protein from adipokines family, that maintain energy homeostasis of the body and deter obesity development. Impaired transfer of leptin signals to hypothalamus leads to leptin resistance and its adverse complications. Understanding
G. A. Chumakova +4 more
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Obesity and cancer: existing and new hypotheses for a causal connection [PDF]
, 2018 Existing explanations of obesity-associated cancer emphasise direct mutagenic effects of dietary components or hormonal imbalance. Some of these hypotheses are reviewed briefly, but recent evidence suggests a major role for chronic inflammation in cancer
Darlington, L. Gail +2 more
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Gender dimorphism in skeletal muscle leptin receptors, serum leptin and insulin sensitivity. [PDF]
PLoS ONE, 2008 To determine if there is a gender dimorphism in the expression of leptin receptors (OB-R170, OB-R128 and OB-R98) and the protein suppressor of cytokine signaling 3 (SOCS3) in human skeletal muscle, the protein expression of OB-R, perilipin A, SOCS3 and ...
Borja Guerra +8 more
doaj +1 more source
Leptin signalling, obesity and prostate cancer: molecular and clinical perspective on the old dilemma [PDF]
, 2015 The prevalence of global obesity is increasing. Obesity is associated with general cancer-related morbidity and mortality and is a known risk factor for development of specific cancers.
Alfraidi, Albandri +5 more
core +5 more sources
Leptin regulates gonadotropins and steroid receptors in the rats ovary
Nutrición Hospitalaria, 2013 The leptin hormone is important to satiety and an important link between the nutritional status and reproductive processes. Owing to the contradictory effects of leptin on the ovary and the failure to clarify the precise mechanism by which leptin affects
Fernanda Silveira Cavalcante +2 more
doaj +1 more source
Frontiers in Immunology, 2018 Leptin is a cytokine, produced mainly by mature adipocytes, that regulates the central nervous system, mainly to suppress appetite and stimulate energy expenditure.
Natália R. T. Amorim +10 more
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The role of leptin resistance in the development of thyroid neoplasia
Mìžnarodnij Endokrinologìčnij Žurnal, 2023 Background. Leptin influences energy metabolism, as it is able to inform the central nervous system about adipose tissue reserves, and is also an important neuroendocrine regulator.
O.S. Miroshnichenko
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