Mutations of LH and FSH receptors
Journal of Endocrinological Investigation, 2000 Gonadotropins control male and female gonadal function by acting through specific receptors. The recent description of several mutations in LH and FSH receptors has significantly improved our understanding of the pathophysiology of several sexual disorder. Both gain- and loss-of-function germline mutations leading to constitutive receptor activation or
P, Beck-Peccoz, R, Romoli, L, Persani
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LHCGR phamacodynamic effects during follicular maturation [PDF]
Frontiers in EndocrinologyLuteinizing hormone (LH) and human chorionic gonadotropin (hCG) are glycoprotein hormones that regulate human reproduction. Although they bind the same G protein-coupled membrane receptor (LHCGR) and have high percentage of structural identity, recent ...
Carmela Perri +4 more
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The Expression of Serum Antibodies against Gonadotropin-releasing Hormone (GnRH1), Progonadoliberin-2, Luteinizing Hormone (LH), and Related Receptors in Patients with Gastrointestinal Dysfunction or Diabetes Mellitus [PDF]
Drug Target Insights, 2014 Gonadotropin-releasing hormone (GnRH) 1 and 2 and luteinizing hormone (LH) receptors have been described in the gastrointestinal tract. We have previously demonstrated antibodies in serum against GnRH1 in patients with gastrointestinal dysfunction and ...
Bodil Roth +2 more
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The LH/hCG Axis in Endometrial Cancer: A New Target in the Treatment of Recurrent or Metastatic Disease [PDF]
Obstetrics and Gynecology International, 2010 Endometrial cancer (EC) is a hormone-dependent cancer that currently represents the most frequent malignancy of the female reproductive tract. The involvement of steroid hormones in EC etiology and progression has been reported.
A. Arcangeli +3 more
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Changes of FSH and LH receptors expressions in rat testis after methamphetamine exposure [PDF]
Songklanakarin Journal of Science and Technology (SJST), 2021 Methamphetamine (METH), the most widely used psychostimulant in Thailand, has been reported to have harmful effects on testicular functions and sperm quality, but its mechanisms are still unclear.
Paweena Kaewman +2 more
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Journal of Animal Reproduction and Biotechnology, 2021 Mutations in the luteinizing hormone/chorionic gonadotropin receptors (LH/CGRs), representatives of the G protein-coupled receptor family, have been rapidly identified over the last 20 years.
Kwan-Sik Min +6 more
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STUDY OF LUTEINIZING HORMONE RECEPTORS IN OVARIAN TISSUES OF BUFFALOES [PDF]
Assiut Veterinary Medical Journal, 1989 information regarding to gain of the present study is The aim the intake of LH by normal follicular and luteal cells of buffalo inactive smooth ovaries.
HODA H. HATEM +5 more
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Sex Steroid Inhibition of LH Induction of the LH Receptor [PDF]
Journal of Andrology, 1987 Testosterone and estrogen were tested as possible mediators of the prolactin‐dependent LH induction of LH receptors in hypophysectomized adult male rats. Animals were injected s.c. with saline, prolactin (100 μg/day), or combinations of testosterone (1 mg/day) or estrogen (1 mg/day) and prolactin for 7 days following a 7‐day period of hypophysectomy ...
W B, Zipf, M O, Hussein
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Canine LH Receptors Expression in Non-neoplastic and Neoplastic Tissues [PDF]
Throughout most of the developed world, surgical sterilization via gonadectomy has become a common tool for combating the overpopulation of unwanted dogs as well as to eliminate the risk of reproductive diseases in pet dogs. In the dog as in other normal
Zwida, Khawla
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Improvement of fertility parameters with Tribulus Terrestris and Anacyclus Pyrethrum treatment in male rats [PDF]
International Brazilian Journal of Urology, 2019 Objective Anacyclus Pyrethrum (AP) and Tribulus Terrestris (TT) have been reported as male infertility treatment in several studies; however, in Iranian traditional medicine these two plants are prescribed simultaneously.
Dariush Haghmorad +7 more
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