Expanding functions of lipoprotein receptors
Journal of Lipid Research, 2009 Lipoprotein receptors are evolutionarily ancient proteins that are expressed on the surface of many cell types. Beginning with the appearance of the first primitive multicellular organisms, several structurally and functionally distinct families of ...
Joachim Herz +3 more
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Characterization of the low-density lipoprotein receptors family and identification of vitellogenin receptors in Mugil cephalus [PDF]
Scientific ReportsVitellogenin receptors (VtgRs) are pivotal to the successful reproductive event in oviparous species by mediating the uptake of vitellogenin (Vtg) into developing oocytes, ensuring proper yolk formation and embryonic development.
Andrea Miccoli, Basilio Randazzo
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Lipidome remodeling in primary biliary cholangitis [PDF]
Lipids in Health and DiseasePrimary biliary cholangitis (PBC) is a chronic, cholestatic liver disease characterized by progressive destruction of intrahepatic bile ducts, impaired bile flow, and complex disturbances in bile acid and lipid metabolism.
Magdalena Rogalska +5 more
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Expression of LDL receptor-related proteins (LRPs) in common solid malignancies correlates with patient survival [PDF]
, 2017 LDL receptor-related proteins (LRPs) are transmembrane receptors involved in endocytosis, cell-signaling, and trafficking of other cellular proteins. Considerable work has focused on LRPs in the fields of vascular biology and neurobiology.
Gilder, Andrew S. +4 more
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Lipoprotein Receptors Redundantly Participate in Entry of Hepatitis C Virus. [PDF]
PLoS Pathogens, 2016 Scavenger receptor class B type 1 (SR-B1) and low-density lipoprotein receptor (LDLR) are known to be involved in entry of hepatitis C virus (HCV), but their precise roles and their interplay are not fully understood. In this study, deficiency of both SR-
Satomi Yamamoto +14 more
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Interdependent Impact of Lipoprotein Receptors and Lipid-Lowering Drugs on HCV Infectivity
Cells, 2021 The HCV replication cycle is tightly associated with host lipid metabolism: Lipoprotein receptors SR-B1 and LDLr promote entry of HCV, replication is associated with the formation of lipid-rich membranous organelles and infectious particle assembly ...
Francisco J. Zapatero-Belinchón +10 more
doaj +1 more source
Frontiers in Microbiology, 2023 IntroductionIn clinical settings, dairy cows are often attacked by pathogenic bacteria after delivery, especially Staphylococcus aureus (S. aureus). Neutrophils have long been regarded as essential for host defense against S. aureus.
Kai Zhang +15 more
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LRP1 loss in airway epithelium exacerbates smoke-induced oxidative damage and airway remodeling
Journal of Lipid Research, 2022 The LDL receptor-related protein 1 (LRP1) partakes in metabolic and signaling events regulated in a tissue-specific manner. The function of LRP1 in airways has not been studied. We aimed to study the function of LRP1 in smoke-induced disease.
Itsaso Garcia-Arcos +13 more
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Liver Transplantation to Provide Low-Density-Lipoprotein Receptors and Lower Plasma Cholesterol in a Child with Homozygous Familial Hypercholesterolemia [PDF]
, 1984 A six-year-old girl with severe hypercholesterolemia and atherosclerosis had two defective genes at the low-density-lipoprotein (LDL) receptor locus, as determined by biochemical studies of cultured fibroblasts.
Cummings +9 more
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Unpacking and understanding the impact of proprotein convertase subtilisin/kexin type 9 inhibitors on apolipoprotein B metabolism [PDF]
, 2017 No abstract ...
Packard, Chris J.
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