Results 21 to 30 of about 783,628 (249)

New horizons for lipoprotein receptors: communication by β-propellers

Journal of Lipid Research, 2013
The lipoprotein receptor (LR) family constitutes a large group of structurally closely related receptors with broad ligand-binding specificity. Traditionally, ligand binding to LRs has been anticipated to involve merely the complement type repeat (CR ...
Olav M. Andersen, Robert Dagil, Birthe B. Kragelund   +2 more
doaj   +1 more source

LRP-1 and LRP-2 receptors function in the membrane neuron. Trafficking mechanisms and proteolytic processing in Alzheimer’s disease

Frontiers in Physiology, 2012
Low density lipoprotein receptor-related protein (LRP) belongs to the low-density lipoprotein receptor family, generally recognized as cell surface endocytic receptors, which bind and internalize extracellular ligands for degradation in lysosomes ...
Carlos eSpuch, Saida eOrtolano, Carmen eNavarro   +2 more
doaj   +1 more source

Cell-associated heparin-like molecules modulate the ability of LDL to regulate PCSK9 uptake[S]

Journal of Lipid Research, 2019
Proprotein convertase subtilisin/kexin type 9 (PCSK9) targets the LDL receptor (LDLR) for degradation, increasing plasma LDL and, consequently, cardiovascular risk.
Adri M. Galvan, John S. Chorba
doaj   +1 more source

Triglyceride-rich lipoprotein metabolism in unique VLDL receptor, LDL receptor, and LRP triple-deficient mice

Journal of Lipid Research, 2005
The very low density lipoprotein receptor (VLDLR), low density lipoprotein receptor (LDLR), and low density lipoprotein receptor-related protein (LRP) are the three main apolipoprotein E-recognizing endocytic receptors involved in the clearance of ...
Sonia M. S. Espirito Santo, Patrick C.N. Rensen, Jeltje R. Goudriaan, André Bensadoun, Niels Bovenschen, Peter J. Voshol, Louis M. Havekes, Bart J.M. van Vlijmen   +7 more
doaj   +1 more source

Effects of deletion of the Streptococcus pneumoniae lipoprotein diacylglyceryl transferase gene lgt on ABC transporter function and on growth in vivo [PDF]

, 2012
Lipoproteins are an important class of surface associated proteins that have diverse roles and frequently are involved in the virulence of bacterial pathogens.
Hermans Peter W. M., Brown, J.S., Durmort Claire, Jeremy S. Brown, Jonathan M Cohen, Emilie Camberlein, Hermans, P.W.M., Camberlein Emilie, Durmort, C, Vernet Thierry, MacDonald, N, Chimalapati, S, Claire Durmort, Jeremy S Brown, Timothy Mitchell, Suneeta Chimalapati, Cohen, J.M., Camberlein, E, Peter W. M. Hermans, Brown, JS, Chimalapati, S., Hermans, PWM, Vernet, T., Chimalapati Suneeta, Camberlein, E., Mitchell, T., Mitchell Timothy, MacDonald, N., Peter W M Hermans, Nathanael MacDonald, Thierry Vernet, Vernet, T, Cohen, JM, Cohen Jonathan M., Brown Jeremy S., MacDonald Nathanael, Durmort, C., Jonathan M. Cohen, Mitchell, T   +38 more
core   +3 more sources

The characterisation of the ectodomain shedding of the low density lipoprotein receptor [PDF]

, 2009
Includes abstract. Includes bibliographical references (leaves 142-155)
Parker, Ayesha
core   +1 more source

Regulation of macrophage apoE secretion and sterol efflux by the LDL receptor

Journal of Lipid Research, 2007
Factors that regulate apolipoprotein E (apoE) secretion by macrophages will have important effects on vessel wall lipid flux and atherosclerosis. Macrophages express the LDL receptor, which binds apoE with high affinity and could thereby affect the net ...
Danijela Lucic, Zhi Hua Huang, De Sheng Gu, Michael K. Altenburg, Nobuyo Maeda, Theodore Mazzone   +5 more
doaj   +1 more source

The role of dimerisation in the cellular trafficking of G-protein-coupled receptors [PDF]

, 2010
The concept that G-protein-coupled receptors can exist as homomeric and/or heteromeric complexes is now well established. Despite this, how dynamic such interactions are and if this may be modulated during receptor trafficking remain topics of debate ...
Milligan, Graeme
core   +1 more source

Characterization of lipoprotein receptors on rat Fu5AH hepatoma cells.

Journal of Lipid Research, 1987
The rat hepatoma cell line Fu5AH has the unusual property of accumulating massive amounts of cholesteryl ester upon incubation with hypercholesterolemic serum, and especially when incubated with beta-very low density lipoproteins (beta-VLDL) from ...
G Friedman, M E Wernette-Hammond, D Y Hui, R W Mahley, T L Innerarity   +4 more
doaj   +1 more source

Lipoprotein lipase mediates an increase in the selective uptake of high density lipoprotein-associated cholesteryl esters by hepatic cells in culture

Journal of Lipid Research, 1998
In this study the effect of lipoprotein lipase (LPL) on the selective uptake of high density lipoprotein (HDL) cholesteryl esters (CE) by hepatic cells was investigated.
Franz Rinninger, Tatjana Kaiser, W. Alexander Mann, Nicolette Meyer, Heiner Greten, Ulrike Beisiegel   +5 more
doaj   +1 more source