Results 11 to 20 of about 122,271 (244)

Expanding functions of lipoprotein receptors

Journal of Lipid Research, 2009
Lipoprotein receptors are evolutionarily ancient proteins that are expressed on the surface of many cell types. Beginning with the appearance of the first primitive multicellular organisms, several structurally and functionally distinct families of ...
Joachim Herz, Ying Chen, Irene Masiulis, Li Zhou   +3 more
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Characterization of the low-density lipoprotein receptors family and identification of vitellogenin receptors in Mugil cephalus [PDF]

Scientific Reports
Vitellogenin receptors (VtgRs) are pivotal to the successful reproductive event in oviparous species by mediating the uptake of vitellogenin (Vtg) into developing oocytes, ensuring proper yolk formation and embryonic development.
Andrea Miccoli, Basilio Randazzo
doaj   +2 more sources

Lipoprotein Receptors Redundantly Participate in Entry of Hepatitis C Virus. [PDF]

PLoS Pathogens, 2016
Scavenger receptor class B type 1 (SR-B1) and low-density lipoprotein receptor (LDLR) are known to be involved in entry of hepatitis C virus (HCV), but their precise roles and their interplay are not fully understood. In this study, deficiency of both SR-
Satomi Yamamoto, Takasuke Fukuhara, Chikako Ono, Kentaro Uemura, Yukako Kawachi, Mai Shiokawa, Hiroyuki Mori, Masami Wada, Ryoichi Shima, Toru Okamoto, Nobuhiko Hiraga, Ryosuke Suzuki, Kazuaki Chayama, Takaji Wakita, Yoshiharu Matsuura   +14 more
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Interdependent Impact of Lipoprotein Receptors and Lipid-Lowering Drugs on HCV Infectivity

Cells, 2021
The HCV replication cycle is tightly associated with host lipid metabolism: Lipoprotein receptors SR-B1 and LDLr promote entry of HCV, replication is associated with the formation of lipid-rich membranous organelles and infectious particle assembly ...
Francisco J. Zapatero-Belinchón, Rina Ötjengerdes, Julie Sheldon, Benjamin Schulte, Belén Carriquí-Madroñal, Graham Brogden, Laura M. Arroyo-Fernández, Florian W. R. Vondran, Benjamin Maasoumy, Thomas von Hahn, Gisa Gerold   +10 more
doaj   +1 more source

Staphylococcus aureus increases Prostaglandin E2 secretion in cow neutrophils by activating TLR2, TLR4, and NLRP3 inflammasome signaling pathways

Frontiers in Microbiology, 2023
IntroductionIn clinical settings, dairy cows are often attacked by pathogenic bacteria after delivery, especially Staphylococcus aureus (S. aureus). Neutrophils have long been regarded as essential for host defense against S. aureus.
Kai Zhang, Kai Zhang, Yan Jia, Yan Jia, Yinghong Qian, Xueying Jiang, Xueying Jiang, Shuangyi Zhang, Shuangyi Zhang, Bo Liu, Bo Liu, Jinshan Cao, Jinshan Cao, Yongli Song, Wei Mao, Wei Mao   +15 more
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LRP1 loss in airway epithelium exacerbates smoke-induced oxidative damage and airway remodeling

Journal of Lipid Research, 2022
The LDL receptor-related protein 1 (LRP1) partakes in metabolic and signaling events regulated in a tissue-specific manner. The function of LRP1 in airways has not been studied. We aimed to study the function of LRP1 in smoke-induced disease.
Itsaso Garcia-Arcos, Sangmi S. Park, Michelle Mai, Roger Alvarez-Buve, Lillian Chow, Huchong Cai, Nathalie Baumlin-Schmid, Christina W. Agudelo, Jennifer Martinez, Michael D. Kim, Abdoulaye J. Dabo, Matthias Salathe, Ira J. Goldberg, Robert F. Foronjy   +13 more
doaj   +1 more source

Functions of lipoprotein receptors in neurons

Journal of Lipid Research, 2004
The LDL receptor (LDLR) family is comprised of several multifunctional cell surface proteins that bind and endocytose ligands with diverse biological functions.
Uwe Beffert, Peggy C. Stolt, Joachim Herz   +2 more
doaj   +1 more source

Lipolytic remnants of human VLDL produced in vitro: effect of HDL levels in the lipolysis mixtures on the apoCs to apoE ratio and metabolic properties of VLDL core remnants

Journal of Lipid Research, 2000
To determine the role of high-density lipoprotein (HDL) as an acceptor of lipolytic surface remnants of very low density lipoprotein (VLDL) in the metabolism of VLDL core remnants, we examined the effect of HDL levels in the VLDL lipolysis mixture on 1 ...
Byung Hong Chung, Nassrin Dashti
doaj   +1 more source

Isolation and characterization of two distinct species of human very low density lipoproteins lacking apolipoprotein E

Journal of Lipid Research, 1996
We have isolated two fractions of very low density lipoprotein particles in human plasma that lack apolipoprotein (apo) E by combined anti-apoE and heparin affinity chromatography of whole plasma followed by ultracentrifugation.
E Campos, S Jäckle, G Chi Chen, R J Havel   +3 more
doaj   +1 more source

Ganglioside embedded in reconstituted lipoprotein binds cholera toxin with elevated affinity[S]

Journal of Lipid Research, 2010
The ability to exogenously present cell-surface receptors in high-affinity conformations in a synthetic system offers an opportunity to provide host cells with protection from pathogenic toxins.
Daniel A. Bricarello, Emily J. Mills, Jitka Petrlova, John C. Voss, Atul N. Parikh   +4 more
doaj   +1 more source