Results 131 to 140 of about 24,569 (232)

Interleukin-1β Expression Is Required for Lysophosphatidic Acid-Induced Lymphangiogenesis in Human Umbilical Vein Endothelial Cells

open access: yesInternational Journal of Inflammation, 2011
Lysophosphatidic acid (LPA) is a lipid mediator which binds to G-protein-coupled receptors and regulates various cellular responses, including inflammation of endothelial cells.
Chih-Hsin Lin, JenHer Lu, Hsinyu Lee
doaj   +1 more source

Frontiers of antifibrotic therapy in systemic sclerosis [PDF]

open access: yes, 2017
Although fibrosis is becoming increasingly recognized as a major cause of morbidity and mortality in modern societies, targeted anti-fibrotic therapies are still not approved for most fibrotic disorders. However, intense research over the last decade has
Abraham, DJ   +5 more
core  

Roles of lipid mediators in early pregnancy events

open access: yesReproductive Medicine and Biology
Background Early pregnancy events, including embryo implantation, are critical for maintaining a healthy pregnancy and facilitating childbirth. Despite numerous signaling pathways implicated in establishing early pregnancy, a comprehensive understanding ...
Shizu Aikawa, Yasushi Hirota
doaj   +1 more source

Potassium channels of the K2P-family control the activity of neuronal cells - TRESK as regulator of inflammatory hyperalgesia [PDF]

open access: yes, 2015
Das Empfinden von Schmerz ist für uns überlebenswichtig. Chronischer Schmerz hingegen hat seine physiologische Bedeutung verloren und wird als eigenes Krankheitsbild angesehen. Schmerzempfindung beginnt mit der Nozizeption.
Kollert, Sina
core  

LPAR2 Regulates LPA-Induced Osteoclast Sealing Zone Dynamics [PDF]

open access: yes, 2010
Bone metastasis is an excruciating consequence of multiple primary cancers, and is commonly treated with bisphosphonate drugs. Osteoclasts, bone-resorbing cells vital to proper bone remodeling and fracture healing, are responsible for the formation of ...
Meyer, Stephanie
core  

Pharmacological Blockade of LPAR1 Does Not Provide Neuroprotection in a Rat Model of Ocular Hypertensive Glaucoma. [PDF]

open access: yesTransl Vis Sci Technol
Kocherlakota S   +6 more
europepmc   +1 more source

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