Results 61 to 70 of about 23,013 (268)

A Comprehensive Review on Nutrition, Phytochemistry, Pharmacology and Food Application Perspectives of Bioactive Rich Superfruits

open access: yesFuture Postharvest and Food, EarlyView.
The review critically evaluated and compared the selected superfruit phytochemistry, their bioactive composition and the key health benefits majorly emphasizing the antioxidant potential. It has highlighted the translational challenges in formulating functional foods by addressing the issues related to delivery system, bioavailability mechanism and the
Sharath Kumar Nagaraja   +3 more
wiley   +1 more source

Endogenous and Exogenous Melatonin Exposure Attenuates Hepatic MT1 Melatonin Receptor Protein Expression in Rat

open access: yesAntioxidants, 2019
Melatonin receptors are highly relevant for the hepatoprotective effects of the pineal hormone melatonin after experimental hemorrhagic shock in rats. In this study, we sought to determine the spatial expression pattern and a putative regulation of two ...
Alexander M. Mathes   +6 more
doaj   +1 more source

Mechanisms of spinal glial activation in chemotherapy‐induced peripheral neuropathy: Focus on microglia and astrocytes

open access: yesIbrain, EarlyView.
Chemotherapy‐induced peripheral neuropathy (CIPN) remains a major clinical challenge, with central sensitization considered an important pathological mechanism in its occurrence and persistence. This review focuses on spinal astrocytes and microglia, systematically summarizing the pathological mechanisms of spinal glial cells involved in CIPN caused by
Long Gu, Song Cao, Yonghuai Feng
wiley   +1 more source

Molecular imprinting for neurology: Materials, applications, and limitations

open access: yesIbrain, EarlyView.
Molecularly imprinted materials: diagnostic, therapeutic and research applications in neurology. Molecularly imprinted materials offer high specificity and affinity for target molecules in neurological applications. This review highlights their synthesis, characterisation, and use in diagnostics, research and therapeutics.
Xiaohan Ma   +3 more
wiley   +1 more source

Neurobiology, Pathophysiology, and Treatment of Melatonin Deficiency and Dysfunction

open access: yesThe Scientific World Journal, 2012
Melatonin is a highly pleiotropic signaling molecule, which is released as a hormone of the pineal gland predominantly during night. Melatonin secretion decreases during aging. Reduced melatonin levels are also observed in various diseases, such as types
Rüdiger Hardeland
doaj   +1 more source

Potential neuroprotective and therapeutic agents and their mechanisms for irradiation‐induced brain injury

open access: yesIbrain, EarlyView.
In this review, agents such baicalein, troxerutin, epigallocatechin gallate, quercetin, melatonin, valproic acid, lithium, neurosteroid progesterone, as well as minocycline have been implicated as neuroprotective agents for irradiation‐induced neurological deficits. Also, agents such as glucocorticoids, methylphenidate, vitamin E, bisdemethoxycurcumin,
Seidu A. Richard   +2 more
wiley   +1 more source

Duration and mode of delivery: Does maternal sleep matter?

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Poor sleep quality in late pregnancy has been identified as a risk factor for operative deliveries. In this study, we investigated the associations between maternal sleep throughout pregnancy and its impact on both the duration and mode of delivery.
Hilla Parttimaa   +5 more
wiley   +1 more source

Toward an idiographic understanding of the role of sleep‐mood dynamics in adolescents' internalizing symptoms

open access: yesJCPP Advances, EarlyView.
Abstract Background Adolescence is marked by increased vulnerability to sleep disturbances and mood disorders. Understanding how day‐to‐day changes in sleep and mood are linked within the same individual is crucial for clarifying sleep's role in emerging internalizing disorders. However, the extent to which an adolescent's fluctuations in sleep predict
Konstantin Drexl   +4 more
wiley   +1 more source

Molecular Investigations on Angiogenesis and Oxidative Stress in Roe Deer (Capreolus capreolus) Bucks' Testes Throughout the Reproductive Cycle

open access: yesJournal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT Animals with seasonal reproductive cycles, as the Roe deer (Capreolus capreolus), have developed mechanisms to synchronize reproduction with the environmental cycle in order to optimize reproductive success through melatonin. Angiogenesis and oxidative stress are key processes in spermatogenesis, contributing to testicular remodeling and ...
Ilaria Troisio   +7 more
wiley   +1 more source

Improving sleep on the inpatient general, non‐stroke neurology service: A quasi‐experimental interventional trial

open access: yesJournal of Hospital Medicine, EarlyView.
Abstract Background Hospitalized patients often experience poor sleep, which is associated with worse health outcomes, increased rates of delirium, and readmissions. Objective To improve overnight sleep for clinically stable general neurology patients at a single academic center.
Noor F. Shaik   +19 more
wiley   +1 more source

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