Results 71 to 80 of about 10,275 (190)
Pregabalin Efficacy in Treatment of Chronic Neurogenic Cough
The Laryngoscope, Volume 136, Issue 11, Page 4938-4944, November 2026.The use of neuromodulators for chronic cough has increased; however, the choice of medication, dosing regimen, and duration are still unclear. This longitudinal study of 95 adults taking pregabalin, 75 mg twice daily, for CNC demonstrated 78% improvement or resolution of cough, 17% unchanged, 1% worse cough, with a mean of 6 weeks of therapy, and only ...
Jacqui Allen +3 more
wiley +1 more source
Neurokinin-1 Receptor Inhibition and Cough
American Journal of Respiratory and Critical Care Medicine, 2021 Richard D. Turner, Surinder S. Birring
openaire +3 more sources
Molecular Pain, 2007 Background Acute cutaneous neurogenic inflammation initiated by activation of transient receptor potential vanilloid-1 (TRPV1) receptors following intradermal injection of capsaicin is mediated mainly by dorsal root reflexes (DRRs).
Zou Xiaoju +4 more
doaj +1 more source
Approaches to the Modulation of Abdominal Pain
Canadian Journal of Gastroenterology, 1999 Despite their high prevalence and significant economic impact on the health care system, functional gastrointestinal disorders have evaded successful therapy.
Emeran A Mayer, Tony Lembo, Lin Chang
doaj +1 more source
Journal of Internal Medicine, Volume 300, Issue 5, Page 590-609, November 2026.Abstract Polyendocrine metabolic ovarian syndrome (PMOS), previously known as polycystic ovary syndrome, affects 10%–13% of women of reproductive age and remains underdiagnosed despite its substantial health burden. The introduction of the new PMOS nomenclature in 2026 reflects a fundamental shift in understanding the condition as a lifelong endocrine ...
Maria Forslund +5 more
wiley +1 more source
Frontiers in Endocrinology, 2019 Neurokinin B (NKB) and its cognate receptor (NK3R) are emerging as important components of the neuroendocrine regulation of reproduction. Unlike mammalian tac3, which encodes only one mature peptide (namely NKB), two mature peptides are predicted for ...
Naama Mizrahi +5 more
doaj +1 more source
International Journal of Cancer, Volume 159, Issue 8, Page 1990-2003, 15 October 2026.Chemotherapy‐induced nausea and vomiting (CINV) remains a significant clinical problem despite modern antiemetics. In particular, antiemetic strategies for emerging cancer therapies lack detailed evaluation. This randomized trial analyzed hourly CINV data for patients with early breast cancer who received either docetaxel plus cyclophosphamide (TC) or ...
Manuel Hörner +16 more
wiley +1 more source
Cellular and Molecular Gastroenterology and Hepatology, 2018 Background & Aims: Tachykinins are involved in physiological and pathophysiological mechanisms in the gastrointestinal tract. The major sources of tachykinins in the gut are intrinsic enteric neurons in the enteric nervous system and extrinsic nerve ...
Ninotchska M. Delvalle +5 more
doaj +1 more source
Role of the Neurokinin-1 Receptors in Ejaculation in Anesthetized Rats
The Journal of Sexual Medicine, 2009 ABSTRACTIntroductionSeveral lines of evidence indicate a role for substance P in the control of ejaculation, although its mode of action needs to be clarified.AimThe effects and sites of action of a selective antagonist for the substance P-preferred receptor (neurokinin-1 receptor subtype; NK1) were investigated in a pharmacological model of ...
Pierre, Clement +5 more
openaire +2 more sources
Interaction of Plant Extracts with Central Nervous System Receptors
Medicines, 2017 Background: Plant extracts have been used in traditional medicine for the treatment of various maladies including neurological diseases. Several central nervous system receptors have been demonstrated to interact with plant extracts and components ...
Kenneth Lundstrom +2 more
doaj +1 more source