Results 1 to 10 of about 4,528 (158)
Neurokinin B and pre-eclampsia: a decade of discovery [PDF]
Reproductive Biology and Endocrinology, 2010 At the start of the last decade, we provided evidence that levels of the peptide neurokinin B were highly elevated in pre-eclampsia. We hypothesized that elevated levels of neurokinin B may be an indicator of pre-eclampsia and that treatment with certain
Page Nigel M
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Structural insights into the activation of neurokinin 2 receptor by neurokinin A
Cell Discovery, 2022 Wenjing Sun +10 more
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Essential Role of Histidine for Rapid Copper(II)-Mediated Disassembly of Neurokinin B Amyloid
Biomolecules, 2022 Neurokinin B is a tachykinin peptide involved in a diverse range of neuronal functions. It rapidly forms an amyloid, which is considered physiologically important for efficient packing into dense core secretory vesicles within hypothalamic neurons ...
Bhawantha M. Jayawardena +3 more
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Frontiers in Pharmacology, 2022 Situational syncope, which includes rectally mediated reflexes, is defined as syncope induced by a specific situation. Its pathogenesis generally involves disorders of the autonomic nervous system.
Kentaro Kurogochi +3 more
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Utilizing Peptide Ligand GPCRs to Image and Treat Pancreatic Cancer
Biomedicines, 2018 It is estimated that early detection of pancreatic ductal adenocarcinoma (PDAC) could increase long-term patient survival by as much as 30% to 40% (Seufferlein, T. et al., Nat. Rev. Gastroenterol. Hepatol. 2016, 13, 74–75).
Gail L. Matters, John F. Harms
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The Neurokinin-1 Receptor Is a Target in Pediatric Rhabdoid Tumors
Current Oncology, 2021 Rhabdoid tumors (RT) are among the most aggressive tumors in early childhood. Overall survival remains poor, and treatment only effectively occurs at the cost of high toxicity and late adverse effects. It has been reported that the neurokinin-1 receptor/
Julian Kolorz +13 more
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Tachykinins: Neuropeptides That Are Ancient, Diverse, Widespread and Functionally Pleiotropic
Frontiers in Neuroscience, 2019 Tachykinins (TKs) are ancient neuropeptides present throughout the bilaterians and are, with some exceptions, characterized by a conserved FX1GX2Ramide carboxy terminus among protostomes and FXGLMamide in deuterostomes.
Dick R. Nässel +3 more
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Neurokinin receptors in the gastrointestinal muscle wall: cell distribution and possible roles
Biomolecular Concepts, 2013 The neurokinin receptors are G-protein-linked receptors; three distinct molecules, called neurokinin-1, neurokinin-2, and neurokinin-3 receptors, have been identified.
Vannucchi Maria Giuliana +1 more
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Tachykinin: recent developments and novel roles in health and disease
Biomolecular Concepts, 2014 Over 80 years has passed since the discovery of substance P (SP), and a variety of peptides of the tachykinin (TK) family have been found and investigated.
Onaga Takenori
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Journal of Neuroinflammation, 2011 Background Neurogenic inflammation is orchestrated by a large number of neuropeptides. Tachykinins (substance P, neurokinin A and neurokinin B) are pro-inflammatory neuropeptides that may play an important role in some autoimmune neuroinflammatory ...
Mostafa Gehan A, AL-Ayadhi Laila Y
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