Results 41 to 50 of about 4,528 (158)
Pakistan Armed Forces Medical JournalObjective: To investigate the potential of variable doses of Neurokinin B on histomorphology of epididymis in adult rabbits. Study Design: Laboratory-based experimental study.
Faiqah Ramzan +2 more
doaj +1 more source
Journal of Pharmacological Sciences, 2004 The aim of this work was to verify whether formalin would induce leukocyte recruitment following intraperitoneal (i.p.) injection in rats. Formalin (1.25 – 2.5%) induced cell recruitment, which was concentration- and time-dependent (0 – 24 h).
Júlia M.M. Santos +4 more
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Medullary tachykinin precursor 1 neurons promote rhythmic breathing
eLife, 2023 Rhythmic breathing is generated by neural circuits located in the brainstem. At its core is the preBötzinger Complex (preBötC), a region of the medulla, necessary for the generation of rhythmic breathing in mammals.
Jean-Philippe Rousseau +4 more
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The Distribution of Neurokinin-1 and Neurokinin-2 Receptors in Human Central Airways [PDF]
American Journal of Respiratory and Critical Care Medicine, 2000 Abstract The precise locations of neurokinin (NK)-1 and NK-2 receptors in human airways, and their role in airway inflammatory diseases, have not been carefully examined. To determine the distribution of NK-1 and NK-2 receptors in human central airways, and to determine whether their distribution was different in smokers, we examined ...
MAPP C. E. +10 more
openaire +6 more sources
Therapeutic Advances in Reproductive Health, 2023 Vasomotor symptoms of menopause (VMS), otherwise known as hot flashes, can significantly impact women’s quality of life. Up to 87% of women report hot flashes during or after their menopause transition, and can last for a median duration of 7.4 years ...
Melissa Conklin, Nanette Santoro
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Neurokinin-1 Receptor Resensitization Precedes Receptor Recycling [PDF]
, 2020 Following agonist binding, neurokinin-1 receptors undergo rapid desensitization followed by internalization and recycling. Desensitization requires receptor phosphorylation but does not require internalization, whereas resensitization is thought to ...
V J Bennett, S A Perrine, M A Simmons
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Examining Neurokinin Signaling in Etiology of Tamoxifen Induced Hot Flashes [PDF]
, 2023 Tamoxifen is a selective estrogen modulator used to treat breast cancer patients to reduce the reoccurrence of estrogen receptor-positive breast cancer. However, treatment with tamoxifen leads to serious side effects, including hot flashes.
Budek, Weronika Ewa
core
Opioidergic pathways and kisspeptin in the regulation of female reproduction in mammals
Frontiers in Neuroscience, 2022 Endogenous opioid peptides have attracted attention as critical neuropeptides in the central mechanism regulating female reproduction ever since the discovery that arcuate dynorphin neurons that coexpress kisspeptin and neurokinin B (NKB), which are also
Yoshihisa Uenoyama +4 more
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Neurokinin b signalling in human puberty [PDF]
, 2010 PubMedID: 20456599Recent identification of TAC3 or TACR3 (encoding neurokinin B and its receptor, NK3R, respectively) mutations as the causes of normosmic idiopathic hypogonadotrophic hypogonadism has provided compelling evidence for the involvement of ...
Yuksel B., Topaloglu A.K., Kotan L.D.
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A novel super-potent neurokinin A receptor antagonist containing dehydroalanine. [PDF]
, 1998 We report here the synthesis and preliminary pharmacological characterization of a novel Neurokinin A receptor antagonist. This molecule contains a dehydroalanine residue. It displays a high conformational rigidity and possesses very high activity.
FILIPPELLI, Amelia +13 more
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