Human acute myeloid leukemia cells express Neurokinin-1 receptor, which is involved in the antileukemic effect of Neurokinin-1 receptor antagonists [PDF]
, 2020 The substance P/neurokinin-1 receptor system has been implicated in tumor cell proliferation. Neurokinin-1 receptor has been identified in different solid tumors but not frequently in hematopoietic malignant cells.
Muñoz Sáez, Miguel +6 more
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Tachykinin neuropeptides in cerebellar granule neurons: an immunocytochemical study
European Journal of Histochemistry, 2009 We previously demonstrated that exogenously administered neurokinin A and neurokinin B, but not substance P, increased the sensitivity of cultured cerebellar granule neurons (CGNs) to glutamate.
C Barbato, MT Ciotti
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Expression of substance P, neurokinin 1 receptors(NK1) and neurokinin 3 receptors in the developing mouse retina and in the retina of NK1 knockout mice [PDF]
, 2006 —To complete a series of studies on the expression of substance P and neurokinin receptors in mammalian retinas, we investigated the occurrence of these molecules in developing mouse retinas and in retinas of mice with genetic deletion of the ...
BOSCO, L. +17 more
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Molecular characterisation, expression and localisation of human neurokinin-3 receptor [PDF]
, 1992 The complete amino acid sequence of the human neurokinin-3 receptor was deduced by DNA sequence analysis of human genomic fragments. Comparison of the predicted primary structure with those for the human neurokinin receptors 1 and 2 shows a highly ...
Arkinstall, S.J. +15 more
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Substance P selectively decreases paired pulse depression in the rat hippocampal slice
BMC Neuroscience, 2005 Background Although being widespread in the hippocampus, the role tachykinins play in synaptic transmission is unclear. The effect of substance P on field potentials evoked by stimulation of the Schaffer collateral-commissural fibres and recorded from ...
Davies Stephen N, Wease Kerrie N
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Neuropeptide modulation of lymphatic smooth muscle tone in the canine forelimb
Mediators of Inflammation, 1992 Neurokinin A and B are putative inflammatory mediators. We assessed their ability to alter prenodal lymphatic resistance. Intralymphatic neurokinin A (3.0 × 10−6, 3.0 × 10−5 and 3.0 × 10−4 mol l−1) significantly constricted lymphatics at the two highest ...
David E. Dobbins
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Possible causes and treatment strategies for the estrus and ovulation disorders in dairy cows
The Journal of Reproduction and Development, 2022 The reproductive performance of dairy cows has declined, along with an increase in their milk yield. First-service conception rates in lactating dairy cows are often lower than 50%.
Natsumi ENDO
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Neurokinin B levels in maternal circulation during early pregnancy [PDF]
, 2004 Neurokinin B levels were measured between the 10th-20th weeks of pregnancy, i.e., prior to the development of clinical symptoms, in women who developed preeclampsia or delivered a growth-restricted baby.
Tjoa, May Lee +6 more
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Molecules, 2020 Aprepitant, a lipophilic and small molecular representative of neurokinin 1 receptor antagonists, is known for its anti-proliferative activity on numerous cancer cell lines that are sensitive to Substance P mitogen action.
Paweł K. Halik +5 more
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Frontiers in Endocrinology, 2021 Increasing evidence accumulated during the past two decades has demonstrated that the then-novel kisspeptin, which was discovered in 2001, the known neuropeptides neurokinin B and dynorphin A, which were discovered in 1983 and 1979, respectively, and ...
Yoshihisa Uenoyama +4 more
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