Results 61 to 70 of about 4,528 (158)

Neurokinin A-induced Ca²⁺-responses in mouse taste cells involve activation of both the neurokinin 1 and neurokinin 2 receptors. [PDF]

, 2013
A, Inhibition of Ca2+- responses to neurokinin A (NKA, 300 nM) in an isolated taste cell by the neurokinin 2 receptor (NK-2R) antagonist GR159897 (GR,1 µM) and the neurokinin 1 receptor (NK-1R) antagonist RP67580 (RP, 1 µM).
Jeff Grant (331942)
core   +1 more source

Neurokinin B signaling in puberty: Human and animal studies [PDF]

, 2010
PubMedID: 20176081Recent reports of humans who have normosmic idiopathic hypogonadotropic hypogonadism due to TAC3 or TACR3 (encoding neurokinin B and its receptor, NK3R, respectively) mutations provided compelling evidence for the involvement of ...
Topaloglu A.K.
core   +1 more source

Dexamethasone-sparing strategies in anthracycline and cyclophosphamide-based chemotherapy with a focus on 5-HT3 receptor antagonists: a network meta-analysis

Frontiers in Oncology
BackgroundThe effectiveness of a dexamethasone-sparing strategy in the treatment of breast cancer with anthracycline-cyclophosphamide therapy when combined with first-generation 5-HT3 receptor antagonists (RAs) and neurokinin-1 RAs is unclear.
Daichi Watanabe, Daichi Watanabe, Hirotoshi Iihara, Hirotoshi Iihara, Hirotoshi Iihara, Ryo Kobayashi, Ryo Kobayashi, Hironori Fujii, Ryutaro Mori, Keisuke Kumada, Keisuke Kumada, Masahito Shimizu, Masahito Shimizu, Manabu Futamura, Akio Suzuki, Akio Suzuki   +15 more
doaj   +1 more source

A Neural Circuit Underlying the Generation of Hot Flushes

Cell Reports, 2018
Summary: Hot flushes are a sudden feeling of warmth commonly associated with the decline of gonadal hormones at menopause. Neurons in the arcuate nucleus of the hypothalamus that express kisspeptin and neurokinin B (Kiss1ARH neurons) are candidates for ...
Stephanie L. Padilla, Christopher W. Johnson, Forrest D. Barker, Michael A. Patterson, Richard D. Palmiter   +4 more
doaj   +1 more source

Mapping of neurokinin b in the cat brainstem [PDF]

, 2020
We studied the distribution of neurokinin B-immunoreactive cell bodies and fibers in the cat brainstem using an indirect immunoperoxidase technique. The highest density of immunoreactive fibers was found in the motor trigeminal nucleus, the laminar and ...
Ae J A Narvaez, L A Aguilar, J Rioja, I Cuadrado, Sabio, Incyl, Ae R Coven˜as, Alfonso X El, Ae J Rioja, Ae J A Aguirre, Anat Embryol, J A Aguirre, Ae L A Aguilar   +12 more
core  

Involvement of Substance P and the Neurokinin-1 Receptor in Radiation-Induced Hair Loss in Mice

Journal of Pharmacological Sciences, 2010
We investigated the involvement of substance P (SP) and the neurokinin-1 receptor (NK1 R) in the development of radiation-induced hair loss in mice.
Kouichi Yamamoto, Naoko Kureyama, Keiko Asano, Toshiji Ikeda, Atsushi Yamatodani   +4 more
doaj   +1 more source

Will elinzanetant, a neurokinin receptor antagonist, have a role in the treatment of hot flashes? [PDF]

Introduction The use of hormonal treatment for the vasomotor symptoms (VSM) associated with the menopause is back in favor, as the adverse effects reported in the early 2000s have been dispelled.
Doggrell, Sheila A
core   +1 more source

Salmeterol inhibits neurokinin receptor expression. [PDF]

, 2014
LAD2 human mast cells were treated with fluticasone (1 uM) or salmeterol (1 uM) or combination for 20 hr, and C3aR (A), neurokinin receptor 1(TARC1; B), 2 (TARC2; C) and 3 (TARC3; D) expression was measured by flow cytometry.
Robert P. Schleimer (562586), Levente E. Erdos (562584), Adriana Catalli (562582), Victor Karpov (562583), Brian P. Tancowny (562585), Marianna Kulka (95755)   +5 more
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Neurokinin B activates arcuate kisspeptin neurons through multiple tachykinin receptors in the male mouse [PDF]

, 2013
Kisspeptin neurons located in the arcuate nucleus (ARN) coexpress dynorphin and neurokinin B (NKB) and may interact to influence gonadotropin secretion.
de Croft, Simon, Boehm, Ulrich, Herbison, Allan E.   +2 more
core   +1 more source

Serum Spexin, Kisspeptin-1, Substance P, and Neurokinin-1 Receptor Levels in Hyperemesis Gravidarum: A Prospective Paired Follow-Up Study

Cumhuriyet Science Journal
Hyperemesis gravidarum (HG) is characterized by severe nausea and vomiting during pregnancy and may adversely affect both maternal health and fetal development.
Ayça Taş, Dilay Karademir, Tugba Agbektas, Zuhal Tunçbilek, Gülcihan Cinar Kaya, Yavuz Siliğ   +5 more
doaj   +1 more source