Neurokinin-1 receptor: neurokinin-1 receptor, purification and refolding
El receptor Neuroquinin-1 (NK1R) és un GPCR que es troba en el sistema nerviós central i perifèric dels vertebrats i és responsable dels processos fisiològics com la transmissió de dolor, secreció endocrina i exocrina, vasodilatació, modulació de la proliferació cel·lular i molts altres.
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Christina Ruhlmann, Jørn HerrstedtOdense University Hospital, Department of Oncology, Odense, DenmarkAbstract: Chemotherapy-induced nausea and vomiting (CINV) are among the most feared and distressing symptoms experienced by patients with ...
Christina Ruhlmann +1 more
doaj
Placental mRNA Expression of Neurokinin B Is Increased in PCOS Pregnancies with Female Offspring
Current research suggests that polycystic ovary syndrome (PCOS) might originate in utero and implicates the placenta in its pathogenesis. Kisspeptin (KISS1) and neurokinin B (NKB) are produced by the placenta in high amounts, and they have been ...
Georgios K. Markantes +6 more
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Involvement of midbrain tectum neurokinin-mediated mechanisms in fear and anxiety
Electrical stimulation of midbrain tectum structures, particularly the dorsal periaqueductal gray (dPAG) and inferior colliculus (IC), produces defensive responses, such as freezing and escape behavior.
J.C. Brenes +4 more
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Chronic social defeat stress (SDS) is a widely employed preclinical model of depression involving repeated exposure to physical defeats using a resident-intruder model in male mice.
Matthew G. Solomon +5 more
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Recycling and Resensitization of the Neurokinin 1 Receptor [PDF]
Dirk Roosterman +4 more
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Expression of Tacr1 and Gpr83 by spinal projection neurons
Anterolateral system (ALS) projection neurons underlie perception of pain, itch and skin temperature. These cells are heterogeneous, and there have therefore been many attempts to define functional populations.
Wenhui Ma +7 more
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Neurokinin-3 receptor antagonists for vasomotor symptoms in menopause and breast cancer survivorship. [PDF]
Feng NL +3 more
europepmc +1 more source
Perampanel Attenuates Cognitive and Behavioral Deficits and Modulates Hippocampal Tachykinin Expression in Experimental Temporal Lobe Epilepsy. [PDF]
Shishmanova-Doseva M +2 more
europepmc +1 more source
Intracellular pocket and ICL2 motifs govern G-protein coupling bias in NK<sub>1</sub> receptor (TACR1) and NK<sub>2</sub> receptor (TACR2). [PDF]
Petersen JE +5 more
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