Results 81 to 90 of about 623,354 (235)

Neuropeptide Y receptors: a promising target for cancer imaging and therapy.

, 2015
Neuropeptide Y (NPY) was first identified from porcine brain in 1982, and plays its biological functions in humans through NPY receptors (Y1, Y2, Y4 and Y5).
Li, Juan, Wu, Aiguo, Tian, Yuchen
core  

Envolvimento do neuropeptídeo Y na resiliência ao medo condicionado contextual em ratos [PDF]

, 2013
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2013.O neuropeptídeo Y (NPY) é o peptídeo mais abundante no sistema nervoso central (SNC), sendo ...
Lach, Gilliard
core  

Research Progress on Upper Airway Cough Syndrome

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Upper airway cough syndrome (UACS) has been identified as a significant contributor to chronic cough in various national guidelines. However, the complexity of its pathogenesis, the lack of clarity surrounding its diagnostic criteria, and its overlap with other etiologies of chronic cough present considerable challenges in both diagnosis and ...
Wan‐Ting Huang, Jia Chen
wiley   +1 more source

Current Advances of Treatments, Therapeutic Targets, Biomarkers, Novel Drugs, and Machine Learning for Hypopharyngeal Squamous Cell Carcinoma

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Hypopharyngeal squamous cell carcinoma (HSCC) is an aggressive subtype of head and neck squamous cell carcinoma with insidious onset, early metastasis, and dismal prognosis. Conventional multimodal therapy achieves limited survival benefit, highlighting an urgent need for refined precision strategies.
Ce Li, Rui Guan, Rui‐Jie Jiao, Zhi‐Jie Bi, Yang Fu, Yin Wang, Chen‐Yang Xu, Ye Qian, Ran Wei, Sheng‐Da Cao, Wen‐Ming Li, Dong‐Min Wei, Da‐Peng Lei   +12 more
wiley   +1 more source

Neuropeptide signaling in insects

, 2010
Neuropeptides represent the largest single class of signal compounds and are involved in regulation of development, growth, reproduction, metabolism and behavior of insects. Over the last few years there has been a tremendous increase in our knowledge of
Altstein, Miriam, Nässel, Dick R,
core  

Evidence of parental care as a newly identified reproductive isolating barrier

Journal of Animal Ecology, EarlyView.
Behavioural variation can contribute to reproductive isolation and can be an important driver of speciation. Here, we show that a previously undescribed mechanism, parental care, can function as a postzygotic reproductive isolating barrier when dysregulated in hybrids.
Colby Behrens, Meghan F. Maciejewski, Alexandra Sumarli, Gina Lucas, German Lagunas‐Robles, Kieran Samuk, Alison M. Bell   +6 more
wiley   +1 more source

Adeno-associated viral vector-induced overexpression of neuropeptide Y Y2 receptors in the hippocampus suppresses seizures.

, 2010
Gene therapy using recombinant adeno-associated viral vectors overexpressing neuropeptide Y in the hippocampus exerts seizure-suppressant effects in rodent epilepsy models and is currently considered for clinical application in patients with intractable ...
Gøtzsche, Casper R, Elbrønd-Bek, Heidi, Merab Kokaia, Ängehagen, Mikael,, Woldbye, David P D, Olesen, Mikkel V, Nikitidou, Litsa,, Toft Sörensen, Andreas, Hansen, Thomas V O, Litsa Nikitidou, Ängehagen, Mikael, Thomas v. O. Hansen, Christiansen, Søren H, Olesen, Mikkel V., Kokaia, Merab, Andreas T. Sørensen, Kanter-Schlifke, Irene, Søren H. Christiansen, Hansen, Thomas v. O., Casper R. Gøtzsche, Kanter Schlifke, Irene,, Sørensen, Andreas Toft, Christiansen, Søren Hofman Oliveira, Kanter Schlifke, Irene, Irene Kanter-Schlifke, Kokaia, Merab,, Gøtzsche, Casper René, Nikitidou, Litsa, Woldbye, David Paul Drucker, David P. D. Woldbye, Mikael Ängehagen, Heidi Elbrønd-Bek, Toft Sörensen, Andreas,, Lund University., Mikkel V. Olesen   +34 more
core   +1 more source

Calcitonin‐like diuretic hormone influences reproduction in adult female Rhodnius prolixus

Insect Science, EarlyView.
Highlights • CT/DH‐like immunoreactivity is present in female reproductive tissues • CT/DH receptor transcripts are expressed in the fat body and ovaries • RNAi knockdown of CT/DH receptors reduces egg number and hatching rate • Rhopr‐CT/DH increases RhoprVg1 and RhoprVgR expression in ovaries in vitro • Rhopr‐CT/DH stimulates oviduct contractions in a
Areej N. Al‐Dailami, Ian Orchard, Angela B. Lange   +2 more
wiley   +1 more source

Energy homeostasis : crosstalk between adipose tissue and the human hypothalamus [PDF]

There is a worldwide epidemic of obesity. Weight rise is a consequence of continuous positive energy balance which leads to accumulation of body fat. Recent insights into adipose tissue (AT) biology have led to the conclusion that the adipocyte is not
Kos, Katarina
core  

Adaptation of the invasive pest Drosophila suzukii to a specialized nutritional niche

Insect Science, EarlyView.
Unlike most Drosophila larvae that feed on spoiled food, Drosophila suzukii larvae thrive on ripening fruits and consequently face a low‐protein, high‐carbohydrate nutritional challenge. Comparisons of growth among D. suzukii, D. biarmipes, and D. melanogaster larvae across diets with varying protein‐to‐carbohydrate ratios demonstrate that D.
Yan Hou, Ying Zhen
wiley   +1 more source