Results 111 to 120 of about 27,803 (242)

Can serum neuropeptide levels help diagnose pediatric migraine? A prospective case–control study

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective The objective of this study was to examine the serum levels of vasoactive neuropeptides (calcitonin gene‐related peptide [CGRP], pituitary adenylate cyclase‐activating peptide‐38 [PACAP‐38], substance P [SP], and vasoactive intestinal peptide [VIP], which have been linked to the pathophysiology of migraine in adults) in pediatric ...
Sibğatullah Ali Orak, Muzaffer Polat, Mert Pak, Çisil Çerçi Kubur, Aslı Kübra Atasever, Celil Yilmaz, Fatma Taneli, Ahmet Angin, Beyhan Cengiz Özyurt   +8 more
wiley   +1 more source

Galcanezumab reduces trigeminal nociception and is effective in preclinical models of migraine and trigeminal autonomic cephalalgias

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives/Background This study was undertaken to assess the therapeutic efficacy of galcanezumab in preclinical models of migraine and cluster headache and to determine potential shared trigeminovascular mechanisms of action. Galcanezumab is a humanized monoclonal antibody that binds to the neuropeptide calcitonin gene‐related peptide ...
Marta Vila‐Pueyo, Peter J. Goadsby, Kirk W. Johnson, Philip R. Holland   +3 more
wiley   +1 more source

Calcitonin gene‐related peptide and headache: Comparison of two commonly used assay kits highlights the perils of measuring neuropeptides with enzyme‐linked immunosorbent assays

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives/Background This study was undertaken to test the ability of a widely used enzyme‐linked immunosorbent assay (ELISA) kit to detect calcitonin gene‐related peptide (CGRP) isoforms to better understand currently published clinical data.
Michael L. Garelja, Tayla A. Rees, Debbie L. Hay   +2 more
wiley   +1 more source

Changes in brainstem habituation during onabotulinumtoxinA treatment in chronic migraine: A prospective case–control study

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives/Background Chronic migraine is a debilitating neurological disorder characterized by central sensitization and impaired brainstem habituation. OnabotulinumtoxinA is an established prophylactic treatment for chronic migraine, yet its effects on central trigeminal sensory processing remain incompletely understood.
Gerlinde Freimark, Sebastian Strauss, Lucas H. Overeem, Mira P. Fitzek, Kristin S. Lange, Carolin L. Höhne, Uwe Reuter, Robert Fleischmann, Bianca Raffaelli   +8 more
wiley   +1 more source

Evaluation of the performance of ChatGPT‐4 and ChatGPT‐4o as a learning tool in endodontics

International Endodontic Journal, EarlyView.
Abstract Aims The aim of this study was to evaluate the accuracy and consistency of responses given by two different versions of Chat Generative Pre‐trained Transformer (ChatGPT), ChatGPT‐4, and ChatGPT‐4o, to multiple‐choice questions prepared from undergraduate endodontic education topics at different times of the day and on different days ...
Esra Arılı Öztürk, Ceren Turan Gökduman, Burhan Can Çanakçi   +2 more
wiley   +1 more source

Psychoneuroendocrine stress response in female and male youth with major depressive disorder

Journal of Child Psychology and Psychiatry, EarlyView.
Background Exposure to psychosocial stress is one of the strongest risk factors for major depressive disorder (MDD) in youth, but underlying neurobiological mechanisms are poorly understood. Previous studies on the neuroendocrine stress response in youth with MDD are scarce, limited to cortisol, and rarely considered sex differences.
Anka Bernhard, Nikola Fann, Andreas G. Chiocchetti, Katharina Ackermann, Anne Martinelli, Christine M. Freitag   +5 more
wiley   +1 more source

Neuroendocrine mechanisms responsible for elevated gonadotrophin‐releasing hormone and luteinising hormone pulses in polycystic ovary syndrome

Journal of Neuroendocrinology, EarlyView.
Abstract Polycystic ovary syndrome (PCOS) is the leading cause of anovulatory infertility in premenopausal individuals with ovaries worldwide. Despite the diagnostic features of anovulation, ovarian cysts, and hyperandrogenemia, which indicate that ovary dysfunction is the cause of the syndrome, changes in central neuroendocrine circuits are a ...
Aleisha M. Moore
wiley   +1 more source

Transcriptome-Wide Identification of Neuropeptides and Neuropeptide Receptors in the Twenty-Eight-Spotted Ladybird <i>Henosepilachna vigintioctopunctata</i>. [PDF]

Insects
Lei Q, Wang Z, Yao S, Lin A, Zhang Y, Sun C, Liu X, Du M, Liu X, An S.   +9 more
europepmc   +1 more source

The impact of re‐characterizing metastatic pancreatic neuroendocrine tumors: A prospective study

Journal of Neuroendocrinology, EarlyView.
Abstract The biology of metastatic pancreatic neuroendocrine tumors (panNET) may alter over time. It remains to be defined if, how, and when this patient group should be recommended to re‐evaluate the characteristics of their disease. This prospective single‐center, longitudinal cohort study at Uppsala University Hospital, Sweden (NCT03130205 ...
Kazhan Mollazadegan, Johan Botling, Britt Skogseid, Barbro Eriksson, Lovisa Falkman, Liang Zhang, Ieva Lase, Staffan Welin, Anders Sundin, Joakim Crona   +9 more
wiley   +1 more source

Peptidergic Systems and Neuroblastoma. [PDF]

Int J Mol Sci
Sánchez ML, Coveñas R.
europepmc   +1 more source