Results 31 to 40 of about 204,197 (323)

The Role of NPY in the Regulation of Bone Metabolism

open access: yesFrontiers in Endocrinology, 2022
Bone diseases are the leading causes of disability and severely compromised quality of life. Neuropeptide Y (NPY) is a multifunctional neuropeptide that participates in various physiological and pathological processes and exists in both the nerve system ...
Qing-Chang Chen   +2 more
doaj   +1 more source

Neuropeptide Y Y2 receptor in health and disease [PDF]

open access: yesBritish Journal of Pharmacology, 2008
British Journal of Pharmacology (2008) 155, 1307; doi:10.1038/bjp.2008 ...
Ambikaipakan Balasubramaniam   +1 more
openaire   +4 more sources

Coordinated RNA-Seq and peptidomics identify neuropeptides and G-protein coupled receptors (GPCRs) in the large pine weevil Hylobius abietis, a major forestry pest [PDF]

open access: yes, 2018
Hylobius abietis (Linnaeus), or large pine weevil (Coleoptera, Curculionidae), is a pest of European coniferous forests. In order to gain understanding of the functional physiology of this species, we have assembled a de novo transcriptome of H. abietis,
Davies, Shireen-Anne   +7 more
core   +1 more source

Neuropeptide Y receptors: a promising target for cancer imaging and therapy

open access: yesRegenerative Biomaterials, 2015
Neuropeptide Y (NPY) was first identified from porcine brain in 1982, and plays its biological functions in humans through NPY receptors (Y1, Y2, Y4 and Y5).
Juan Li, Yuchen Tian, A. Wu
semanticscholar   +1 more source

Sex Differences in the Neuropeptide Y System and Implications for Stress Related Disorders

open access: yesBiomolecules, 2020
The neuropeptide Y (NPY) system is emerging as a promising therapeutic target for neuropsychiatric disorders by intranasal delivery to the brain. However, the vast majority of underlying research has been performed with males despite females being twice ...
Roxanna J. Nahvi, Esther L. Sabban
doaj   +1 more source

What doesn't kill you makes you stranger: Dipeptidyl peptidase-4 (CD26) proteolysis differentially modulates the activity of many peptide hormones and cytokines generating novel cryptic bioactive ligands [PDF]

open access: yes, 2019
Dipeptidyl peptidase 4 (DPP4) is an exopeptidase found either on cell surfaces where it is highly regulated in terms of its expression and surface availability (CD26) or in a free/circulating soluble constitutively available and intrinsically active form.
Aguilar-Pérez, Alexandra   +13 more
core   +1 more source

Antisense mRNA for NPY-Y1 receptor in the medial preoptic area increases prolactin secretion

open access: yesBrazilian Journal of Medical and Biological Research, 1999
We investigated the participation of neuropeptide Y-Y1 receptors within the medial preoptic area in luteinizing hormone, follicle-stimulating hormone and prolactin release.
N.A. Silveira, C.R. Franci
doaj   +1 more source

Influence of Neuropeptide Y and Neuropeptide Y 2 Receptor Variants in Acute Coronary Syndrome [PDF]

open access: yesInternational Journal of Cardiovascular Sciences, 2021
Abstract Background The neuropeptide Y (NPY) is one of the most abundant neurotransmitters in the nervous system. NPY acts as a potent stimulator of angiogenesis, inflammation, and adipogenesis, through the NPY 2 receptor (NPY2R). Changes in the NPY signaling pathway have been linked to Acute Coronary Syndrome (ACS).
Fábia C. S. Soares   +13 more
openaire   +4 more sources

The evolution and variety of RFamide-type neuropeptides: insights from deuterostomian invertebrates [PDF]

open access: yes, 2014
Five families of neuropeptides that have a C-terminal RFamide motif have been identified in vertebrates: (1) gonadotropin-inhibitory hormone (GnIH), (2) neuropeptide FF (NPFF), (3) pyroglutamylated RFamide peptide (QRFP), (4) prolactin-releasing peptide (
Elphick, MR, Mirabeau, O
core   +1 more source

NPF activates a specific NPF receptor and regulates food intake in Pacific abalone Haliotis discus hannai

open access: yesScientific Reports, 2021
Neuropeptides function through G protein-coupled receptors (GPCRs) with high specificity, implying a significant degree of neuropeptide-GPCR coevolution. However, potential neuropeptide signaling systems in non-chordates are relatively elusive.
Kyeong Seop Kim   +3 more
doaj   +1 more source

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