Results 11 to 20 of about 205,018 (263)
GRKs as Modulators of Neurotransmitter Receptors [PDF]
Cells, 2020 Many receptors for neurotransmitters, such as dopamine, norepinephrine, acetylcholine, and neuropeptides, belong to the superfamily of G protein-coupled receptors (GPCRs). A general model posits that GPCRs undergo two-step homologous desensitization: the
Eugenia V. Gurevich +1 more
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Cancer and neurotransmitter receptors
Chinese Medical Journal. In recent years, growing evidence indicates that the nervous system plays an indispensable role in tumor development and metastasis. Elucidating crosstalk between the nervous system and tumor progression has thrived as a hot topic and a new direction ...
Xiaoqiang Wang +4 more
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Mechanism for neurotransmitter-receptor matching [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2020 Significance Neurotransmitter switching generally involves replacement of an excitatory transmitter with an inhibitory transmitter or vice versa and has been linked to changes in animal behavior. There are corresponding switches in postsynaptic receptors that enable continued function of the circuit, but the mechanism by which ...
Nicholas Spitzer, Spitzer Nicholas C
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NeuroImage, 2022 Neurotransmitter receptors modulate signaling between neurons. Thus, neurotransmitter receptors and transporters play a key role in shaping brain function.
Justine Y. Hansen +7 more
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Excitatory and inhibitory receptors utilize distinct post- and trans-synaptic mechanisms in vivo
eLife, 2021 Ionotropic neurotransmitter receptors at postsynapses mediate fast synaptic transmission upon binding of the neurotransmitter. Post- and trans-synaptic mechanisms through cytosolic, membrane, and secreted proteins have been proposed to localize ...
Taisuke Miyazaki +9 more
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Cell Reports, 2023 Summary: Neurotransmitter receptors partition into nanometer-scale subdomains within the postsynaptic membrane that are precisely aligned with presynaptic neurotransmitter release sites.
Samantha S. Olah +12 more
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Neurotransmitter receptors on microglia [PDF]
Stroke and Vascular Neurology, 2016 As the resident immune cells in the central nervous system, microglia have long been hypothesised to promote neuroinflammation and exacerbate neurotoxicity. However, this traditional view has undergone recent revision as evidence has accumulated that microglia exert beneficial and detrimental effects depending on activation status, polarisation ...
Liu, Huan, Leak, Rehana K, Hu, Xiaoming
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Potential Therapeutic Targeting Neurotransmitter Receptors in Diabetes
Frontiers in Endocrinology, 2022 Neurotransmitters are signaling molecules secreted by neurons to coordinate communication and proper function among different sections in the central neural system (CNS) by binding with different receptors.
Xiaohui Pan +5 more
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Frontiers in Immunology, 2022 Many epidemiological reports have indicated an increase in the incidence of breast cancer among psychotic patients, suggesting that the targets of antipsychotics, neurotransmitter receptors, may have a role in tumorigenesis.
Wei Zhang +16 more
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Life, 2021 Epilepsy is characterized by an imbalance in neurotransmitter activity; an increased excitatory to an inhibitory activity. Acetylcholine (ACh), serotonin, and norepinephrine (NE) may modulate neural activity via several mechanisms, mainly through its ...
Enes Akyuz +8 more
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