Results 11 to 20 of about 783,873 (297)

Cancer and neurotransmitter receptors

Chinese Medical Journal
. In recent years, growing evidence indicates that the nervous system plays an indispensable role in tumor development and metastasis. Elucidating crosstalk between the nervous system and tumor progression has thrived as a hot topic and a new direction ...
Xiaoqiang Wang, Muyan Shi, Jie Tian, Weifeng Yu, Jing Ni   +4 more
doaj   +3 more sources

Ubiquitination of Neurotransmitter Receptors and Postsynaptic Scaffolding Proteins [PDF]

Neural Plasticity, 2013
The human brain is made up of an extensive network of neurons that communicate by forming specialized connections called synapses. The amount, location, and dynamic turnover of synaptic proteins, including neurotransmitter receptors and synaptic ...
Amy W. Lin, Heng-Ye Man
doaj   +2 more sources

Correspondence between gene expression and neurotransmitter receptor and transporter density in the human brain

NeuroImage, 2022
Neurotransmitter receptors modulate signaling between neurons. Thus, neurotransmitter receptors and transporters play a key role in shaping brain function.
Justine Y. Hansen, Ross D. Markello, Lauri Tuominen, Martin Nørgaard, Elena Kuzmin, Nicola Palomero-Gallagher, Alain Dagher, Bratislav Misic   +7 more
doaj   +1 more source

Excitatory and inhibitory receptors utilize distinct post- and trans-synaptic mechanisms in vivo

eLife, 2021
Ionotropic neurotransmitter receptors at postsynapses mediate fast synaptic transmission upon binding of the neurotransmitter. Post- and trans-synaptic mechanisms through cytosolic, membrane, and secreted proteins have been proposed to localize ...
Taisuke Miyazaki, Megumi Morimoto-Tomita, Coralie Berthoux, Kotaro Konno, Yoav Noam, Tokiwa Yamasaki, Matthijs Verhage, Pablo E Castillo, Masahiko Watanabe, Susumu Tomita   +9 more
doaj   +1 more source

Acute reorganization of postsynaptic GABAA receptors reveals the functional impact of molecular nanoarchitecture at inhibitory synapses

Cell Reports, 2023
Summary: Neurotransmitter receptors partition into nanometer-scale subdomains within the postsynaptic membrane that are precisely aligned with presynaptic neurotransmitter release sites.
Samantha S. Olah, Dean J. Kareemo, William C. Buchta, Brooke L. Sinnen, Carley N. Miller, Hannah S. Actor-Engel, Sara E. Gookin, Christina S. Winborn, Mason S. Kleinjan, Kevin C. Crosby, Jason Aoto, Katharine R. Smith, Matthew J. Kennedy   +12 more
doaj   +1 more source

Neurotransmitter regulation of neural development: acetylcholine and nicotinic receptors

Anais da Academia Brasileira de Ciências, 2002
Several neurotransmitter systems have been related to developmental processes during the past decade. In this review, we discuss the evidence that the nicotinic acetylcholine receptors could have an additional function during development that may be ...
TORRÃO ANDRÉA S., BRITTO LUIZ R.G.
doaj   +1 more source

Potential Therapeutic Targeting Neurotransmitter Receptors in Diabetes

Frontiers in Endocrinology, 2022
Neurotransmitters are signaling molecules secreted by neurons to coordinate communication and proper function among different sections in the central neural system (CNS) by binding with different receptors.
Xiaohui Pan, Xiaohui Pan, Shibing Tao, Shibing Tao, Nanwei Tong, Nanwei Tong   +5 more
doaj   +1 more source

Systematic Analysis of Neurotransmitter Receptors in Human Breast Cancer Reveals a Strong Association With Outcome and Uncovers HTR6 as a Survival-Associated Gene Potentially Regulating the Immune Microenvironment

Frontiers in Immunology, 2022
Many epidemiological reports have indicated an increase in the incidence of breast cancer among psychotic patients, suggesting that the targets of antipsychotics, neurotransmitter receptors, may have a role in tumorigenesis.
Wei Zhang, Wei Zhang, Wei Zhang, Lintai Li, Lintai Li, Jianxuan Li, Jianxuan Li, Haiyan Yu, Haiyan Yu, Fengping Zheng, Bin Yan, Wanxia Cai, Yumei Chen, Lianghong Yin, Donge Tang, Yong Xu, Yong Dai   +16 more
doaj   +1 more source

Immunoreactivity of Muscarinic Acetylcholine M2 and Serotonin 5-HT2B Receptors, Norepinephrine Transporter and Kir Channels in a Model of Epilepsy

Life, 2021
Epilepsy is characterized by an imbalance in neurotransmitter activity; an increased excitatory to an inhibitory activity. Acetylcholine (ACh), serotonin, and norepinephrine (NE) may modulate neural activity via several mechanisms, mainly through its ...
Enes Akyuz, Zuleyha Doganyigit, Yam Nath Paudel, Betul Koklu, Emin Kaymak, Chiara Villa, Alina Arulsamy, Mohd. Farooq Shaikh, Orrin Devinsky   +8 more
doaj   +1 more source

Total ganglioside ablation at mouse motor nerve terminals alters neurotransmitter release level [PDF]

, 2010
Neuronal membrane gangliosides, forming a large family of sialylated glycosphingolipids, have been hypothesized to play important roles in synaptic transmission.
Furukawa, K., Plomp, J.J., Todorov, B., Willison, H.J., Zitman, F.M.P.   +4 more
core   +2 more sources