Results 11 to 20 of about 214,427 (207)
GRKs as Modulators of Neurotransmitter Receptors [PDF]
Cells, 2020 Many receptors for neurotransmitters, such as dopamine, norepinephrine, acetylcholine, and neuropeptides, belong to the superfamily of G protein-coupled receptors (GPCRs). A general model posits that GPCRs undergo two-step homologous desensitization: the
Eugenia V. Gurevich +1 more
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Neurotransmitter receptors on microglia [PDF]
Stroke and Vascular Neurology, 2016 As the resident immune cells in the central nervous system, microglia have long been hypothesised to promote neuroinflammation and exacerbate neurotoxicity. However, this traditional view has undergone recent revision as evidence has accumulated that microglia exert beneficial and detrimental effects depending on activation status, polarisation ...
Liu, Huan, Leak, Rehana K, Hu, Xiaoming
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Palmitoylation as a Functional Regulator of Neurotransmitter Receptors
Neural Plasticity, 2018 The majority of neuronal proteins involved in cellular signaling undergo different posttranslational modifications significantly affecting their functions.
Vladimir S. Naumenko, Evgeni Ponimaskin
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Cancer and neurotransmitter receptors
Chinese Medical Journal. In recent years, growing evidence indicates that the nervous system plays an indispensable role in tumor development and metastasis. Elucidating crosstalk between the nervous system and tumor progression has thrived as a hot topic and a new direction ...
Xiaoqiang Wang +4 more
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Ubiquitination of Neurotransmitter Receptors and Postsynaptic Scaffolding Proteins [PDF]
Neural Plasticity, 2013 The human brain is made up of an extensive network of neurons that communicate by forming specialized connections called synapses. The amount, location, and dynamic turnover of synaptic proteins, including neurotransmitter receptors and synaptic ...
Amy W. Lin, Heng-Ye Man
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Mechanism for neurotransmitter-receptor matching [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2020 SignificanceNeurotransmitter switching generally involves replacement of an excitatory transmitter with an inhibitory transmitter or vice versa and has been linked to changes in animal behavior. There are corresponding switches in postsynaptic receptors that enable continued function of the circuit, but the mechanism by which receptor expression is ...
Dena R Hammond-Weinberger +2 more
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Pharmacological Research, 2023 Neuronal nicotinic acetylcholine receptors (nAChRs) are widely distributed in both the peripheral and the central nervous systems. nAChRs exert a crucial modulatory influence on several brain biological processes; they are involved in a variety of ...
Federica Bono +8 more
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Neurotransmitter regulation of neural development: acetylcholine and nicotinic receptors
Anais da Academia Brasileira de Ciências, 2002 Several neurotransmitter systems have been related to developmental processes during the past decade. In this review, we discuss the evidence that the nicotinic acetylcholine receptors could have an additional function during development that may be ...
TORRÃO ANDRÉA S., BRITTO LUIZ R.G.
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NeuroImage, 2022 Neurotransmitter receptors modulate signaling between neurons. Thus, neurotransmitter receptors and transporters play a key role in shaping brain function.
Justine Y. Hansen +7 more
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Excitatory and inhibitory receptors utilize distinct post- and trans-synaptic mechanisms in vivo
eLife, 2021 Ionotropic neurotransmitter receptors at postsynapses mediate fast synaptic transmission upon binding of the neurotransmitter. Post- and trans-synaptic mechanisms through cytosolic, membrane, and secreted proteins have been proposed to localize ...
Taisuke Miyazaki +9 more
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