Results 21 to 30 of about 1,489 (115)

Induction of synapse formation by de novo neurotransmitter synthesis

open access: yesNature Communications, 2022
Neuronal communication relies on matching different neurostransmitter types with their appropriate receptors. The authors here demonstrate that release of a novel neurotransmitter from presynaptic terminals can induce both the accumulation and activation
Scott R. Burlingham   +10 more
doaj   +1 more source

Acute reorganization of postsynaptic GABAA receptors reveals the functional impact of molecular nanoarchitecture at inhibitory synapses

open access: yesCell Reports, 2023
Summary: Neurotransmitter receptors partition into nanometer-scale subdomains within the postsynaptic membrane that are precisely aligned with presynaptic neurotransmitter release sites.
Samantha S. Olah   +12 more
doaj  

Conditional protein tagging methods reveal highly specific subcellular distribution of ion channels in motion-sensing neurons

open access: yeseLife, 2020
Neurotransmitter receptors and ion channels shape the biophysical properties of neurons, from the sign of the response mediated by neurotransmitter receptors to the dynamics shaped by voltage-gated ion channels.
Sandra Fendl   +2 more
doaj   +1 more source

Mechanism of Allosteric Modulation of the Cys-loop Receptors

open access: yesPharmaceuticals, 2010
The cys-loop receptor family is a major family of neurotransmitter-operated ion channels. They play important roles in fast synaptic transmission, controlling neuronal excitability, and brain function.
Paul Whiteaker   +2 more
doaj   +1 more source

Opioids and Their Receptors: Present and Emerging Concepts in Opioid Drug Discovery II

open access: yesMolecules, 2022
A few neurotransmitter systems have fascinated the research community, as muchas the opioid system (i.e., opioid ligands and their receptors) [...]
Richard M. Van Rijn, Mariana Spetea
doaj   +1 more source

Glutamate at the Vertebrate Neuromuscular Junction: From Modulation to Neurotransmission

open access: yesCells, 2019
Although acetylcholine is the major neurotransmitter operating at the skeletal neuromuscular junction of many invertebrates and of vertebrates, glutamate participates in modulating cholinergic transmission and plastic changes in the last.
Maria Nicol Colombo, Maura Francolini
doaj   +1 more source

Ubiquitination of Neurotransmitter Receptors and Postsynaptic Scaffolding Proteins

open access: yesNeural Plasticity, 2013
The human brain is made up of an extensive network of neurons that communicate by forming specialized connections called synapses. The amount, location, and dynamic turnover of synaptic proteins, including neurotransmitter receptors and synaptic ...
Amy W. Lin, Heng-Ye Man
doaj   +1 more source

Neurochemical Organization of the Drosophila Brain Visualized by Endogenously Tagged Neurotransmitter Receptors

open access: yesCell Reports, 2020
Summary: Neurotransmitters often have multiple receptors that induce distinct responses in receiving cells. Expression and localization of neurotransmitter receptors in individual neurons are therefore critical for understanding the operation of neural ...
Shu Kondo   +9 more
doaj  

Altered expression of genes encoding neurotransmitter receptors in GnRH neurons of proestrous mice

open access: yesFrontiers in Cellular Neuroscience, 2016
Gonadotropin-releasing hormone (GnRH) neurons play a key role in the central regulation of reproduction. In proestrous female mice, estradiol triggers the pre-ovulatory GnRH surge, however, its impact on the expression of neurotransmitter receptor genes ...
Csaba Vastagh   +4 more
doaj   +1 more source

Possible involvement of neuropeptide and neurotransmitter receptors in Adenomyosis

open access: yesReproductive Biology and Endocrinology, 2021
Background Accumulating data indicate that sensory nerve derived neuropeptides such as substance P and calcitonin gene related-protein (CGRP) can accelerate the progression of endometriosis via their respective receptors, so can agonists to their ...
Xiaofang Xu   +3 more
doaj   +1 more source

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