Results 181 to 190 of about 2,466,892 (329)

Sympathetic Shift and Insular Alteration: Unravelling the Link Between Anxiety and Heart Rate Variability in Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Anxiety and autonomic dysfunction are frequent non‐motor symptoms of Parkinson's disease (PD). Their relationship, as well as the neural mechanisms underlying this relationship, remain unexplored. Objectives We aimed to investigate the relationship between cardiovascular functions and anxiety in PD and the structural neural changes ...
Lucia Ricciardi, Alessandra Fanciulli, Francescopaolo P. Cucinotta, Bryony Ishihara, Ioana Cociasu, Fahd Baig, Michael Hart, Erlick Pereira, Francesca Morgante, Elena Makovac   +9 more
wiley   +1 more source

Nicotinic Modulation of Fast-Spiking Neurons in Rat Somatosensory Cortex across Development. [PDF]

eNeuro
Haga CW, Koenig J, Cramer N, Chandra R, Keller A.   +4 more
europepmc   +1 more source

Neuronal Reshaping of the Tumor Microenvironment in Tumorigenesis and Metastasis: Bench to Clinic

Medicine Advances, EarlyView.
This graphical abstract illustrates the multidimensional crosstalk between neurons and tumor microenvironment as well as targeted intervention strategies identified in the study. It highlights three core interaction axes: nerve‐tumor crosstalk mediated by neurotransmitters and neurotrophic factors, neuro‐vascular communication driving angiogenesis via ...
Yimao Wu, Ruowei Sun, Shuai Ren, Gokhan Zengin, Mengyao Li   +4 more
wiley   +1 more source

The Central Cholinergic Synapse: A Primer. [PDF]

Int J Mol Sci
Klein J.
europepmc   +1 more source

Enhancing Selective Brain Cancer Therapy: Integrating Nanomedicine and Molecular Dynamics to Target the Cancerous Lipid Composition

Nano Select, EarlyView.
Improving selectivity within therapeutic design is critical to ensure targeted delivery to brain tumors. Targeting the cellular membrane composition distinctive of the blood–brain barrier and brain cancer cells is explored in this review. Nanomedicine can be utilized for precise tumor recognition, and detailed mechanistic interactions of therapeutics ...
Mahnoor Kadri, Dominique de Jong‐Hoogland, Martin B. Ulmschneider   +2 more
wiley   +1 more source

Nicotine and neuronal nicotinic acetylcholine receptors: unraveling the mechanisms of nicotine addiction. [PDF]

Front Neurosci
Jiang J, Li X, Hu AF, Zhou GJ, Gao YH, Xu C, Wu XM, Wang HJ.   +7 more
europepmc   +1 more source

Association of a Lifestyle Risk Index With Visceral and Subcutaneous Adipose Tissue in the German National Cohort (NAKO)

Obesity, EarlyView.
ABSTRACT Objective This cross‐sectional study examined a Lifestyle Risk Factor Index (LSRI) in relation to adiposity measures including visceral adipose tissue (VAT) in the German National Cohort (NAKO). Methods Based on self‐reports at baseline among 30,920 of > 205,000 NAKO eligible participants with magnetic resonance imaging (MRI) scans, one point ...
Gertraud Maskarinec, Rebecca Klapp, Ute Nöthlings, Matthias B. Schulze, Fabian Bamberg, Jürgen Machann, Sabrina Schlesinger, Michael Leitzmann, Anja Sedlmeier, Patricia Bohmann, Susanne Rospleszcz, Johanna Nattenmüller, Tobias Haueise, Karen Steindorf, Thoralf Niendorf, Christopher L. Schlett, Karin Halina Greiser, Leo Panreck, Jakob Linseisen, Christina‐Alexandra Conzen, Sylvia Gastell, Tamara Schikowski, Henry Völzke, Robin Bülow, Annette Peters, Fiona Niedermayer, Rudolf Kaaks, Heiko Becher, André Karch, Klaus Berger, Thomas Keil, Lilian Krist, Michael Hoffmeister, Ute Mons, Boerge Schmidt, Andreas Stang, Rafael Mikolajczyk, Alexander Kluttig, Wolfgang Lieb, Cara Övermöhle, Antje Hebestreit, Kathrin Günther, Volker Harth, Nadia Obi, Stefanie Castell, Robyn Kettlitz, Katharina Nimptsch, Tobias Pischon   +47 more
wiley   +1 more source

A spatial covariance ¹²³I-5IA-85380 SPECT study of α4β2 nicotinic receptors in dementia with Lewy bodies. [PDF]

J Neurol
Harrison JR, Colloby SJ, O'Brien JT, Taylor JP.   +3 more
europepmc   +1 more source

Investigation of the Mechanism of Cinnamaldehyde in Irritable Bowel Syndrome Based via Network Pharmacology, Molecular Docking, and Animal Experiments

Pediatric Discovery, EarlyView.
Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu, Boqing Xu, Chunfang Dai, Yayan Pang, Zhifang Dong   +4 more
wiley   +1 more source

Modulation of Master Transcription Factor Expression of Nile Tilapia Leukocytes via Cholinergic Pathways. [PDF]

Int J Mol Sci
Girón-Pérez MI, Ramírez-Ibarra KM, Covantes-Rosales CE, Girón-Pérez DA, Razura-Carmona FF, Contis-Montes de Oca A, Morales-Montor J, Pavón L, Toledo-Ibarra GA.   +8 more
europepmc   +1 more source