Results 211 to 220 of about 2,426,956 (334)
Abstract Aim To evaluate the effectiveness, safety and cost‐effectiveness of psychosocial interventions for cannabis use disorder (CUD). Methods A systematic review of randomized controlled trials (RCTs; PROSPERO protocol CRD42024553382) of psychosocial interventions for CUD lasting >4 sessions, delivered synchronously, to individuals with CUD aged ≥16
Monika Halicka+11 more
wiley +1 more source
α4β2<sup>*</sup> nicotinic acetylcholine receptors drive human temporal glutamate/GABA balance toward inhibition. [PDF]
Martinello K+7 more
europepmc +1 more source
Abstract Background and Aims There is a longstanding assumption that cigarette smoking stabilizes mood. However, no studies have rigorously evaluated mood stability as people progress from occasional to regular use of tobacco cigarettes. This observational study thus tested two central questions: as smoking rates increase, (1) does the acute mood boost
Ashley D. Kendall+3 more
wiley +1 more source
Impacts of perinatal nicotine exposure on nicotinic acetylcholine receptor expression and glutamatergic synaptic transmission in the mouse auditory brainstem. [PDF]
Wollet M+5 more
europepmc +1 more source
Synthetic cannabinoids in e‐cigarettes seized from English schools
Abstract Background and aims People who use synthetic cannabinoids (SCs) report debilitating side effects and withdrawal symptoms, coupled with dependence. In the UK, SC use was believed to be largely restricted to prison, where they are the most common drug and associated with nearly half of non‐natural deaths, or poly‐drug users in the community who ...
Gyles E. Cozier+17 more
wiley +1 more source
Significance of nicotine and nicotinic acetylcholine receptors in Parkinson's disease. [PDF]
Lin X, Li Q, Pu M, Dong H, Zhang Q.
europepmc +1 more source
Abstract Background and aims Oral nicotine pouches (ONPs) contain varying proportions of freebase nicotine (FBN), with higher FBN expected to increase nicotine delivery across the oral mucosa. Because ONPs contain fewer toxicants than moist snuff and may serve as a reduced harm alternative for smokeless tobacco, we compared how the FBN in ONPs affects ...
Brittney Keller‐Hamilton+10 more
wiley +1 more source
Enhanced prefrontal nicotinic signaling as evidence of active compensation in Alzheimer's disease models. [PDF]
Power SK+4 more
europepmc +1 more source
Abstract Background and aims Despite a steady decline in smoking rates across the United Kingdom (UK) over the past decades, substantial tobacco‐related inequalities persist, particularly among individuals with mental illness. Smoking prevalence in this group has remained largely unchanged, highlighting a major public health concern.
Dimitra Kale+13 more
wiley +1 more source
Human plasma protein bindings of neonicotinoid insecticides and metabolites. [PDF]
Taira K+3 more
europepmc +1 more source