Results 211 to 220 of about 2,426,956 (334)

Effectiveness and safety of psychosocial interventions for the treatment of cannabis use disorder: A systematic review and meta‐analysis

Addiction, EarlyView.
Abstract Aim To evaluate the effectiveness, safety and cost‐effectiveness of psychosocial interventions for cannabis use disorder (CUD). Methods A systematic review of randomized controlled trials (RCTs; PROSPERO protocol CRD42024553382) of psychosocial interventions for CUD lasting >4 sessions, delivered synchronously, to individuals with CUD aged ≥16
Monika Halicka, Thomas L. Parkhouse, Katie Webster, Francesca Spiga, Lindsey A. Hines, Tom P. Freeman, Sabina Sanghera, Sarah Dawson, Craig Paterson, Jelena Savović, Julian P. T. Higgins, Deborah M. Caldwell   +11 more
wiley   +1 more source

α4β2^* nicotinic acetylcholine receptors drive human temporal glutamate/GABA balance toward inhibition. [PDF]

J Physiol
Martinello K, Mascia A, Casciato S, Di Gennaro G, Esposito V, Zoli M, Gotti C, Fucile S.   +7 more
europepmc   +1 more source

Does increasing cigarette use stabilize mood? A real‐time investigation spanning 6 years of adolescence and young adulthood

Addiction, EarlyView.
Abstract Background and Aims There is a longstanding assumption that cigarette smoking stabilizes mood. However, no studies have rigorously evaluated mood stability as people progress from occasional to regular use of tobacco cigarettes. This observational study thus tested two central questions: as smoking rates increase, (1) does the acute mood boost
Ashley D. Kendall, Donald Hedeker, Kathleen R. Diviak, Robin J. Mermelstein   +3 more
wiley   +1 more source

Impacts of perinatal nicotine exposure on nicotinic acetylcholine receptor expression and glutamatergic synaptic transmission in the mouse auditory brainstem. [PDF]

J Physiol
Wollet M, Hernandez A, Nip K, Ginsburg B, Pugh JR, Kim JH.   +5 more
europepmc   +1 more source

Synthetic cannabinoids in e‐cigarettes seized from English schools

Addiction, EarlyView.
Abstract Background and aims People who use synthetic cannabinoids (SCs) report debilitating side effects and withdrawal symptoms, coupled with dependence. In the UK, SC use was believed to be largely restricted to prison, where they are the most common drug and associated with nearly half of non‐natural deaths, or poly‐drug users in the community who ...
Gyles E. Cozier, Matthew Gardner, Sam Craft, Martine Skumlien, Jack Spicer, Rachael Andrews, Alexander Power, Tom Haines, Richard Bowman, Amy E. Manley, Peter Sunderland, Oliver B. Sutcliffe, Stephen M. Husbands, Lindsey Hines, Gillian Taylor, Tom P. Freeman, Jennifer Scott, Christopher R. Pudney   +17 more
wiley   +1 more source

Significance of nicotine and nicotinic acetylcholine receptors in Parkinson's disease. [PDF]

Front Aging Neurosci
Lin X, Li Q, Pu M, Dong H, Zhang Q.
europepmc   +1 more source

Examining the role of freebase nicotine in the harm reduction potential of oral nicotine pouches versus moist snuff: A randomized crossover trial

Addiction, EarlyView.
Abstract Background and aims Oral nicotine pouches (ONPs) contain varying proportions of freebase nicotine (FBN), with higher FBN expected to increase nicotine delivery across the oral mucosa. Because ONPs contain fewer toxicants than moist snuff and may serve as a reduced harm alternative for smokeless tobacco, we compared how the FBN in ONPs affects ...
Brittney Keller‐Hamilton, Hayley Curran, Leanne Atkinson, Sriya Suraapaneni, Alice Hinton, Kirsten Chrzan, Darren Mays, Ahmad El‐Hellani, Clark W. Wilson, Marielle C. Brinkman, Theodore L. Wagener   +10 more
wiley   +1 more source

Enhanced prefrontal nicotinic signaling as evidence of active compensation in Alzheimer's disease models. [PDF]

Transl Neurodegener
Power SK, Venkatesan S, Qu S, McLaurin J, Lambe EK.   +4 more
europepmc   +1 more source

Offering e‐cigarettes for smoking cessation and reduction in people with mental illness (ESCAPE): Protocol for a randomized controlled trial

Addiction, EarlyView.
Abstract Background and aims Despite a steady decline in smoking rates across the United Kingdom (UK) over the past decades, substantial tobacco‐related inequalities persist, particularly among individuals with mental illness. Smoking prevalence in this group has remained largely unchanged, highlighting a major public health concern.
Dimitra Kale, Emma Beard, Yan Ding, Jodi Pervin, Qi Wu, Catherine Arundel, Steve Parrott, Paul Galdas, Michelle Horspool, Simon Hough, Gregor Russell, Suzy Ker, Elena Ratschen, Lion Shahab   +13 more
wiley   +1 more source

Human plasma protein bindings of neonicotinoid insecticides and metabolites. [PDF]

Sci Rep
Taira K, Ikenaka Y, Bonmatin JM, Safer A.   +3 more
europepmc   +1 more source