Results 211 to 220 of about 2,466,892 (329)

High‐ and low‐dose topiramate for the treatment of persons with alcohol use disorder who smoke cigarettes: A randomized control trial

Alcohol, Clinical and Experimental Research, EarlyView.
Participants (n = 236) from three sites were randomly assigned to either placebo, low‐dose topiramate (up to 125 mg/day), or high‐dose topiramate (up to 250 mg/day) for up to 18 weeks. Exploratory analyses indicated that participants treated with the high dose had lower mean percentage of heavy drinking days and drinks per day than those taking the low
Jason D. Robinson, Robert M. Anthenelli, Paul M. Cinciripini, Maher Karam‐Hage, Yong Cui, George Kypriotakis, Nassima Ait‐Daoud Tiouririne   +6 more
wiley   +1 more source

Marine-Derived Ligands of Nicotinic Acetylcholine Receptors in Cancer Research. [PDF]

Mar Drugs
Kasheverov IE, Shelukhina IV, Utkin YN, Tsetlin VI.   +3 more
europepmc   +1 more source

Effects of cannabidiol in alcohol use disorder patients with and without co‐occurring post‐traumatic stress disorder: Tolerability but no evidence for efficacy in two randomized proof‐of‐concept trials

Alcohol, Clinical and Experimental Research, EarlyView.
Two small placebo‐controlled trials evaluated the effects of cannabidiol (CBD) in patients with alcohol use disorder (AUD), with and without co‐occurring post‐traumatic stress disorder (PTSD). CBD was rapidly absorbed and generally well tolerated in dosages of up to 1200 mg/day. Both treatment groups showed large reductions in drinking.
Michael P. Bogenschutz, Esther Blessing, Danielle Dgheim, Dayeon Cho, Jun Zhang, Eugene M. Laska, Charles R. Marmar   +6 more
wiley   +1 more source

Pharmacological and Mechanistic Interventions for Cognitive Impairment Associated With Schizophrenia: A Review of Registered Clinical Trials

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Background Schizophrenia is characterized by positive, negative, and cognitive symptoms. Current pharmacological treatments often fail to address cognitive deficits. In this review of clinical trials, we aim to identify studies that explore neurobiological (non‐psychological) strategies to address Cognitive Impairment Associated with ...
Bahareh Peyrovian, Lena Palaniyappan, Theodore T. Kolivakis, Howard C. Margolese   +3 more
wiley   +1 more source

Effects of Swapping 5HT3 and α7 Residues in Chimeric Receptor Proteins on RIC3 and NACHO Chaperone Actions. [PDF]

Molecules
Yan Z, Oruganti S, Iyer SK, Agarwal K, Gupta M, Adhikari K, Vijayan N, Doda J, Jain V, Lokhande AN, Nair AP, Nallanichakravarthula VSK, Weltzin MM, Loring RH.   +13 more
europepmc   +1 more source

Neurotransmitter signaling in white matter [PDF]

, 2014
Butt, Arthur M., Fern, Robert F., Matute, Carlos   +2 more
core   +1 more source

Trends and patterns of dual use of combustible tobacco and e‐cigarettes among adults in England: A population study, 2016–2024

Addiction, Volume 120, Issue 4, Page 608-619, April 2025.
Abstract Background/Aims E‐cigarettes are frequently used by people who smoke. This study measured how the prevalence and patterns of smoking and vaping (‘dual use’) in England have changed as the vaping market has rapidly evolved. Design Representative monthly cross‐sectional survey, July 2016 to April 2024. Setting England.
Sarah E. Jackson, Sharon Cox, Lion Shahab, Jamie Brown   +3 more
wiley   +1 more source

Excitatory neurotransmission at O₂ receptors in zebrafish gill: It takes two to tango. [PDF]

J Physiol
Nurse CA, Leonard EM.
europepmc   +1 more source

An update of a systematic review and meta‐analyses exploring flavours in intervention studies of e‐cigarettes for smoking cessation

Addiction, Volume 120, Issue 4, Page 770-778, April 2025.
Abstract Aims To determine patterns of e‐cigarette flavour use (sweet, tobacco, menthol/mint) in interventional studies of e‐cigarettes for stopping smoking, and to estimate associations between flavours and smoking/vaping outcomes. Methods Update of secondary data analyses, including meta‐analyses subgrouped by flavour provision and narrative ...
Nicola Lindson, Jonathan Livingstone‐Banks, Ailsa R. Butler, David T. Levy, Phoebe Barnett, Annika Theodoulou, Caitlin Notley, Nancy A. Rigotti, Yixian Chen, Jamie Hartmann‐Boyce   +9 more
wiley   +1 more source

Editorial: Mechanisms of cholinergic transmission in motivation and cognition. [PDF]

Front Mol Neurosci
Francis TC, Klawonn AM.
europepmc   +1 more source