The exposomal imprint on rosacea: More than skin deep
Rosacea reflects systemic and environmental interactions, not just a skin disorder. Key factors include environmental triggers, genetic and microbiome influences, diagnostic gaps in skin of colour and social determinants. Advances in multi‐omics and exposome integration highlight pathways towards precision medicine, prevention and equitable, patient ...
Katerina Grafanaki +3 more
wiley +1 more source
Excitatory neurotransmission at O<sub>2</sub> receptors in zebrafish gill: It takes two to tango. [PDF]
Nurse CA, Leonard EM.
europepmc +1 more source
Safety of upadacitinib in atopic dermatitis in randomized clinical trials across 6 years
The current study found no evidence of cumulative increased safety risks with upadacitinib 15 or 30 mg for up to 6 years and over 9000 patient‐years of safety data in adults and adolescents. There were low rates of adjudicated major adverse cardiovascular events, adjudicated thromboembolic events and malignancies. Abstract Background Atopic dermatitis (
Christopher G. Bunick +13 more
wiley +1 more source
Role of the neurotransmitter-receptor pathway in T-cell tumor immunology and cancer immunotherapy. [PDF]
Fan M, Zhao X.
europepmc +1 more source
Lower density of calretinin‐immunopositive neurons in the putamen of subjects with schizophrenia
Recent neuroimaging and histological studies highlight the striatum as a key area involved in SCH, but the specific impairment of neuronal subtypes in subcortical structures is not fully understood. This study is the first detailed investigation of neuroanatomical changes in the putamen in SCH, specifically examining the density of calretinin ...
Paz Kelmer +4 more
wiley +1 more source
Dual cholinergic and serotonergic excitatory pathways mediate oxygen sensing in the zebrafish gill. [PDF]
Reed M +3 more
europepmc +1 more source
Sleep bruxism: mapping potential direct and indirect risk pathways in EPISONO adult population‐based study. ABSTRACT Aim To explore the direct and indirect pathways through which sociodemographic, psychological, behavioural, and clinical factors influence sleep bruxism (SB).
Eduardo Machado +6 more
wiley +1 more source
Hippocampal Metabolomics Reveal the Mechanism of α-Conotoxin [S9K]TxID Attenuating Nicotine Addiction. [PDF]
Wang M +9 more
europepmc +1 more source
Examining the Influence of Glycemic Management During Sleep on Sleep‐Related Bruxism: A Pilot Study
Stabilisation of blood glucose levels during sleep may improve sleep‐related bruxism (SRB), particularly by suppressing sympathetic nervous system activity. Furthermore, it is expected that these findings will lead to the establishment of new treatment methods for SRB in sleep dentistry.
Tatsuya Taniwaki +5 more
wiley +1 more source
The ATP-mediated cytokine release by macrophages is down-modulated by unconventional α9* nicotinic acetylcholine receptors. [PDF]
Wolf PMK +16 more
europepmc +1 more source

