Results 71 to 80 of about 83,214 (263)

Molecular docking study of Papaver alkaloids to some alkaloid receptors [PDF]

Research Journal of Pharmacognosy, 2017
Background and objectives: More than 40 different alkaloids have been obtained from opium the most important of which are morphine, codeine, papaverine, noscapine and tabaine.
A. Nofallah, Sh. Hooshmand*, M. Gholami, M. Piri   +3 more
doaj  

Alterations in Cortical and Basal Ganglia Levels of Opioid Receptor Binding in a Rat Model of l-DOPA-Induced Dyskinesia

Neurobiology of Disease, 2001
Opioid receptor-binding autoradiography was used as a way to map sites of altered opioid transmission in a rat model of l-DOPA-induced dyskinesia. Rats with unilateral 6-hydroxydopamine lesions of the nigrostriatal pathways sustained a 3-week treatment ...
P.A. Johansson, M. Andersson, K.E. Andersson, M.A. Cenci   +3 more
doaj   +1 more source

Pharmacogenetics of analgesic drugs [PDF]

, 2013
• Individual variability in pain perception and differences in the efficacy of analgesic drugs are complex phenomena and are partly genetically predetermined.
Branford, R, Cregg, R, Gubbay, A, Russo, G, Sato, H   +4 more
core   +1 more source

Effect of butorphanol in combination with xylazine during castration of calves: A randomised trial under field conditions

Veterinary Record, EarlyView.
Abstract Background In horses, cats and dogs, the opioid butorphanol has been proven effective in management of visceral pain and for peri‐ and postoperative pain relief. The aim of this study was to evaluate physiological responses and indicators of noxious stimuli when adding butorphanol to xylazine for sedation of bull calves during surgical ...
Axel Sannö, Lovisa Snygg, Maja Wiklund, Görel Nyman   +3 more
wiley   +1 more source

The Central Reinforcing Properties of Ethanol Are Mediated by Endogenous Opioid Systems: Effects of Mu and Kappa Opioid Antagonists.

Revista Argentina de Ciencias del Comportamiento, 2009
Endogenous opioid systems are implicated in the reinforcing effects of ethanol and may play a substantial role in modulating the central reinforcing effects of ethanol early in ontogeny.
Norman E. Spear, Elena I. Varlinskaya, Michael E Nizhnikov   +2 more
doaj  

The Potential of Methocinnamox as a Future Treatment for Opioid Use Disorder: A Narrative Review

Pharmacy, 2022
The opioid epidemic is an ongoing public health crisis, and the United States health system is overwhelmed with increasing numbers of opioid-related overdoses.
Colleen G. Jordan, Amy L. Kennalley, Alivia L. Roberts, Kaitlyn M. Nemes, Tenzing Dolma, Brian J. Piper   +5 more
doaj   +1 more source

Prospects for Creation of Cardioprotective and Antiarrhythmic Drugs Based on Opioid Receptor Agonists [PDF]

, 2016
It has now been demonstrated that the μ, δ(1), δ(2), and κ(1) opioid receptor (OR) agonists represent the most promising group of opioids for the creation of drugs enhancing cardiac tolerance to the detrimental effects of ischemia/reperfusion (I/R ...
Bailey A, Cowan A, Dhawan BN, Emmerson PJ, Fryer RM, Fryer RM, Fryer RM, Genade S, Grekova TI, Gu H, Haddad GG, Hansen DD, Hess L, Hiranuma T, Huh J, Imai N, Kettler D, Khan MG, Kin H, Kiritsy‐Roy JA, Kisin I, Korobov NV., Krazinski BE, Kulbertus H, Lasukova TV, Lasukova TV, Lasukova TV, Lasukova TV, Lasukova TV, Lishmanov AYu, Lishmanov IuB, Lishmanov IuB, Lishmanov YuB, Liu X, Marson L, Maslov LN, Maslov LN, Maslov LN, Maslov LN, Maslov LN, Maslov LN, Maslov LN, Maslov LN, Metelitsa VI, Mikhailova SD, Monassier JP., Musha T, Panova EI., Pei JM, Platonov AA, Poonyachoti S, Pugsley MK, Pyle WG, Robson P., Saeed RW, Schultz JE, Shi E, Solenkova NV, Stefano GB, Sun HT, Ugdyzhekova DS, Varga EV, Wang GY, Wong GT, Zhang Y   +64 more
core   +1 more source

Psychedelic‐assisted treatment for substance use disorder: A narrative systematic review

Addiction, EarlyView.
Abstract Background and aims This is the first systematic review of the extant literature on all major psychedelic‐assisted treatment for alcohol use disorder (AUD), tobacco use disorder (TUD) and other substance use disorders (SUD). We aimed to summarise the evidence for efficacy of psychedelic‐assisted treatment for AUD, TUD, and SUD; to evaluate its
Theodore Piper, Francesca Small, Sam Brown, Michael Kelleher, Luke Mitcheson, James Rucker, Allan H. Young, John Marsden   +7 more
wiley   +1 more source

Behavioral Effects and Analgesic Profile of Hemoglobin-Derived Valorphin and Its Synthetic Analog in Rodents

Biomedicines, 2023
Valorphin (V1) is a naturally occurring peptide derived from hemoglobin that has been found to have an affinity for opioid receptors and exhibits antinociceptive and anticonvulsant activity.
Petar Todorov, Borislav Assenov, Dimo Angelov, Elena Dzhambazova, Daniela Pechlivanova   +4 more
doaj   +1 more source

Kappa opioid receptor modulation of endometriosis pain in mice

Neuropharmacology, 2021
The kappa opioid receptor is a constituent of the endogenous opioid analgesia system widely expressed in somatosensory nervous pathways and also in endometrial tissues. This work investigates the possible involvement of kappa opioid receptor on the nociceptive, behavioral and histopathological manifestations of endometriosis in a murine model.
Alejandra Escudero-Lara, David Cabañero, Rafael Maldonado   +2 more
openaire   +3 more sources