Results 91 to 100 of about 779,673 (234)

Cancer‐related pain: A bidirectional modulator of cancer progression

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
CRP and tumour progression engage in a dynamic, bidirectional circuit mediated by multiple mechanisms involving neuroimmunology and cancer ‐neuroscience. Analgesic interventions may affect tumour progression, while anticancer therapies can influence pain. Targeting pain in cancer may have promising therapeutic value in cancer progression.
Junzhe He, Yu Zhang, Qian Liu, Biao Yan, Peiwei Chai, Renbing Jia   +5 more
wiley   +1 more source

The Opioid System in Temporal Lobe Epilepsy: Functional Role and Therapeutic Potential

Frontiers in Molecular Neuroscience, 2017
Temporal lobe epilepsy is considered to be one of the most common and severe forms of focal epilepsies. Patients often develop cognitive deficits and emotional blunting along the progression of the disease.
Johannes Burtscher, Christoph Schwarzer
doaj   +1 more source

A Systematic Review of Hypnosis for Clinical Pain Relief

European Journal of Pain, Volume 30, Issue 8, September 2026.
ABSTRACT Background Previous reviews report moderate reductions in clinical pain with hypnotic suggestion but provide only partial views by comparing hypnosis with inactive controls alone or including few studies or mixed control groups. This review comprehensively evaluated the efficacy of hypnosis in reducing clinical pain intensity compared with non‐
Titus H. Yim, Stuart W. G. Derbyshire
wiley   +1 more source

Behavioral meaningful opioidergic stimulation activates kappa receptor gene expression

Brazilian Journal of Medical and Biological Research, 2012
The periaqueductal gray (PAG) has been reported to be a location for opioid regulation of pain and a potential site for behavioral selection in females.
E. Teodorov, M.F.R. Ferrari, D.R. Fior-Chadi, R. Camarini, L.F. Felício   +4 more
doaj   +2 more sources

Expression of adrenergic, acetylcholine and kappa opioid receptors on peripheral blood lymphocytes in patients with herpetic keratitis and those with idiopathic anterior and/or intermediate uveitis

Journal of Ophthalmology
Purpose: To assess the expression of adrenergic, acetylcholine (ACh) and opioid receptors on peripheral blood lymphocytes in patients with herpetic keratitis (HK) and those with idiopathic anterior and/or intermediate uveitis (IAIU). Methods: Thirty one
L. M. Velychko, O. V. Bogdanova, N. I. Khramenko, N. V. Konovalova, G. I. Drozhzhyna, K. V. Sereda   +5 more
doaj   +1 more source

Methods of Assessing Postoperative Pain in Infants (0–12 Months): A Scoping Review

Paediatric and Neonatal Pain, Volume 8, Issue 3, September 2026.
ABSTRACT Infants undergoing surgery experience postoperative pain beyond acute short‐lasting procedural pain and have variable analgesic needs. Assessing pain in this nonverbal population presents challenges for clinicians and parents. Given the short‐ and long‐term effects of pain and its treatment, timely and accurate assessment of pain is vital. The
Jeewan Jyoti, Donna Waters, Sharon Laing, Denise Harrison, Nadia Badawi, Himanshu Popat   +5 more
wiley   +1 more source

Patient‐reported outcomes for monitoring substance use treatment: A systematic review of single‐item measures

Addiction, Volume 121, Issue 9, Page 2292-2316, September 2026.
Abstract Background and aims Measurement‐based care (MBC) is a structured approach using standardized, repeated assessments to monitor treatment progress and guide clinical decision‐making. MBC improves outcomes for substance use treatment but can be time consuming due in part to lengthy assessment tools. Single‐item, patient‐reported outcome measures (
Thomas J. Reese, Hilary A. Tindle, Justin Bachmann, Adam Wright, Jessica S. Ancker, Carolyn M. Audet, Mauli V. Shah, Bryan D. Steitz, Michael H. Levin, Kristopher A. Kast, David Marcovitz, Amanda von Horn, A. Taylor Kelley, John F. P. Bridges   +13 more
wiley   +1 more source

Placenta ingestion by rats enhances d- and k-opioid antinociception, but suppresses m-opioid antinociception [PDF]

, 2004
Ingestion of placenta or amniotic fluid produces a dramatic enhancement of centrally mediated opioid antinociception in the rat. The present experiments investigated the role of each opioid receptor type (m, d, k) in the antinociception-modulating ...
DiPirro, Jean M., Kristal, Dr. Mark B.
core  

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

Allergy, Volume 81, Issue 9, Page 3039-3070, September 2026.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
Franziska Roth‐Walter, Ian M. Adcock, Cristina Benito‐Villalvilla, Rodolfo Bianchini, Leif Bjermer, Gaetano Caramori, Luigi Cari, Kian Fan Chung, Zuzana Diamant, Ibon Eguiluz‐Gracia, Edward F. Knol, Milos Jesenak, Francesca Levi‐Schaffer, Giuseppe Nocentini, Liam O'Mahony, Oscar Palomares, Frank Redegeld, Milena Sokolowska, Betty Van Esch, Marco Zurlo, Cristiana Stellato   +20 more
wiley   +1 more source

Prevalence and Burden of Fatigue Across Disorders of Gut–Brain Interaction: Results From the Rome Foundation Global Epidemiology Study

Alimentary Pharmacology &Therapeutics, Volume 64, Issue 5, Page 659-674, September 2026.
Fatigue is common and burdensome in disorders of gut‐brain interaction and increases with diagnostic overlap. In this global population‐based study, fatigue was associated with female sex, age, BMI, sleep disturbance, higher anxiety and depression scores, greater somatic symptom burden, lower psychological well‐being, antidepressant use, and greater ...
Fleur Veldman, Francesco Innocenti, Imran Aziz, Asma Fikree, Shrikant I. Bangdiwala, Olafur Palsson, Ami D. Sperber, Daniel Keszthelyi   +7 more
wiley   +1 more source