Results 71 to 80 of about 779,673 (234)

Neuropathic pain in cerebral palsy and related genetic conditions: A scoping review of prevalence, characteristics, and management

Developmental Medicine &Child Neurology, EarlyView.
Abstract Aim To map existing evidence on neuropathic pain in cerebral palsy (CP) and related genetic conditions, including prevalence, descriptors, assessment methods, and management. Method Following prospective registration, five databases (Ovid MEDLINE, Embase, CINAHL, Web of Science, Google Scholar) were searched in June 2025.
Aayushi Khillan, Sanya Verma, Hannah Yeomans, Karen Bau, Caitlin Doyle, Monica S. Cooper, David J. Amor, Carolyn Berryman, Adrienne Harvey   +8 more
wiley   +1 more source

Shared dysregulation of complement and phosphorylation pathways in the cerebrospinal fluid of encephalitis, Aicardi–Goutières syndrome, and autism

Developmental Medicine &Child Neurology, EarlyView.
Abstract Aim To identify shared and disorder‐specific molecular alterations across encephalitis, Aicardi–Goutières syndrome (AGS), and autism spectrum disorder (ASD) using cerebrospinal fluid (CSF) proteomics. Method In this cross‐sectional case–control study, mass‐spectrometry‐based proteomics was performed on archived CSF samples collected between ...
Omar H. Shadid, Peter G. Hains, Velda X. Han, Jingya Yan, Michael Griffiths, Ignatius Pang, Sushil Bandodkar, Phillip J. Robinson, Russell C. Dale   +8 more
wiley   +1 more source

The role of the μ-opioid receptors in the mechanism of ethanol-stimulated mesolimbic dopamine release [PDF]

, 2009
textThe goal of this dissertation was to investigate the role of μ-opioid receptors in the mechanism of ethanol-stimulated dopamine release in the nucleus accumbens shell (NAcS) of rats.
Job, Martin Olufemi
core  

Crosstalk Between Kappa Opioid and Dopamine Systems in Compulsive Behaviors

Frontiers in Pharmacology, 2020
The strength of goal-oriented behaviors is regulated by midbrain dopamine neurons. Dysfunctions of dopaminergic circuits are observed in drug addiction and obsessive-compulsive disorder.
Angélica del Pilar Escobar, José Patricio Casanova, José Patricio Casanova, María Estela Andrés, José Antonio Fuentealba   +4 more
doaj   +1 more source

Oral Status in Relation to Demographic, Socioeconomic, Medical and Psychosocial Risk Factors Among Outpatients in Addiction Treatment Centers, Stockholm, Sweden

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Objective To investigate oral status in relation to demographic, socioeconomic, medical and psychosocial risk factors among outpatients receiving treatment for Substance Use Disorder (SUD). Methods This cross‐sectional study included 91 outpatients from Stockholm, Sweden. Oral status was assessed using the Decayed, Missing, Filled Teeth (DMFT)
Sonja Rafat, Stefan Borg, Gunnar Edman, Anders Hammarberg, Patricia De Palma   +4 more
wiley   +1 more source

Swiss Practice Recommendations for Chronic Prurigo Including Prurigo Nodularis

International Journal of Dermatology, EarlyView.
Chronic prurigo, including prurigo nodularis, is a chronic, often treatment‐refractory condition characterized by persistent pruritus and chronic scratch lesions. Advances in the understanding of its underlying pathophysiology have enabled the development of novel targeted therapies; however, management remains challenging due to the expanding range of
Simon M. Mueller, Helmut Beltraminelli, Wolf‐Henning Boehncke, Maximilian Böhm, Antonio Cozzio, Peter Häusermann, Ahmad Jalili, Antonios G. A. Kolios, Claudia Lang, Eva Loos, Christoph Schlapbach, Curdin Conrad   +11 more
wiley   +1 more source

Delta-opioid receptor analgesia is independent of microglial activation in a rat model of neuropathic pain.

PLoS ONE, 2014
The analgesic effect of delta-opioid receptor (DOR) ligands in neuropathic pain is not diminished in contrast to other opioid receptor ligands, which lose their effectiveness as analgesics.
Joanna Mika, Katarzyna Popiolek-Barczyk, Ewelina Rojewska, Wioletta Makuch, Katarzyna Starowicz, Barbara Przewlocka   +5 more
doaj   +1 more source

Cannabis Use Among People Aged 65 and Older: Results From an Intercept Survey in New York City

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Cannabis use among older adults has increased in recent years. Age‐related physiological changes, socio‐ecological factors, and medications may exacerbate potential adverse effects of cannabis and complicate the detection of cannabis use disorder (CUD) in older adults.
Benjamin H. Han, Krish Jagasia, Tyler Simi, Nina Abukahok, Joseph J. Palamar   +4 more
wiley   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Sabine Elisabeth Groeger, Yuxi Zhou, Jiawen Yong, Lei Wang, Sabine Ruf, Joerg Meyle   +5 more
wiley   +1 more source

Individual Differences in Sleep Quality: Exploring the Impact of Temperament on Sleep Through Anxiety and Depression

Personality and Mental Health, Volume 20, Issue 4, November 2026.
ABSTRACT According to the functional ensemble of temperament (FET) model, individual differences in temperament arise from the balance of neurotransmitter systems also crucial for regulating circadian rhythms and sleep, suggesting a strong neurobiological link between temperament and sleep behavior.
Stefano Lasaponara, Angelica Scuderi, Elisa Pellegrini, Ludovica Annarumma, Valentina Piga, Sara Lo Presti, Maurizio Gorgoni   +6 more
wiley   +1 more source