Results 171 to 180 of about 33,193 (249)

Novel Ligands for the Orphan Receptor GPR151 Modulate Morphine Action

open access: yesGenes to Cells, Volume 31, Issue 3, May 2026.
The new GPR151 ligands altered the analgesic effects of morphine. ABSTRACT GPR151 is an orphan G‐protein‐coupled receptor expressed on specific neurons. Its expression has been reported to be upregulated in the dorsal root ganglia in mouse nerve injury models, suggesting a role in pain transmission.
Hijiri Yoshida   +7 more
wiley   +1 more source

Pharmacogenomics and Opioid Efficacy in Sickle Cell Disease. [PDF]

open access: yesMedicina (Kaunas)
Elshaikh RH   +5 more
europepmc   +1 more source

Impact of Opioid‐Free Anesthesia Combined With Enhanced Recovery After Surgery Protocol on Postoperative Recovery Quality in Patients Undergoing Laparoscopic Total Hysterectomy

open access: yesJournal of Obstetrics and Gynaecology Research, Volume 52, Issue 5, May 2026.
ABSTRACT Aim Opioid‐based anesthesia in laparoscopic hysterectomy is associated with adverse effects (e.g., postoperative nausea and vomiting [PONV], ileus, cognitive impairment) that impede recovery. This study evaluates whether opioid‐free anesthesia (OFA) combined with an Enhanced Recovery After Surgery (ERAS) protocol improves postoperative ...
Yingbing Lv   +5 more
wiley   +1 more source

Single-channel observations on the mu-opioid receptor

open access: yesBiophysical Journal, 1986
Smuda, J.W., de Levie, R.
openaire   +2 more sources

Collagen and microvascular alterations contribute to neuromuscular degeneration and disease progression in chronic intestinal pseudo‐obstruction

open access: yesJournal of Internal Medicine, Volume 299, Issue 5, Page 587-603, May 2026.
Abstract Background Chronic intestinal pseudo‐obstruction (CIPO) is a severe gastrointestinal motility disorder that may be idiopathic or associated with systemic disease. In idiopathic cases, the pathophysiological mechanisms remain poorly defined. Although mutations in angiogenic factors have been reported in mitochondrial forms of CIPO, their role ...
Elisa Boschetti   +17 more
wiley   +1 more source

Sex and age differences in mechanical, thermal and wetness perception across skin sites at risk of pressure ulcers: A quantitative sensory testing study

open access: yesExperimental Physiology, Volume 111, Issue 5, Page 2553-2563, 1 May 2026.
Abstract Pressure ulcers can be common in the elderly, and loss of sensation can play a fundamental role in the development of these injuries. The aim of this study was to assess the effects of age and sex on non‐noxious thermal and wetness perception (via magnitude estimation), alongside pressure‐ and thermal‐pain thresholds, at the heel, sternum and ...
Miriam Martini   +8 more
wiley   +1 more source

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