Results 161 to 170 of about 33,193 (249)

A Membrane‐Centric Plasma Lipidomic Signature of Response to Long‐Acting Naltrexone in Alcohol Use Disorder

open access: yesAddiction Biology, Volume 31, Issue 5, May 2026.
In this responder‐enriched lipidomic substudy, response to long‐acting naltrexone in alcohol use disorder was associated with coordinated remodelling of plasma membrane phospholipids. The signature involved PEMT‐related PC/PE shifts, Lands‐cycle acyl chain editing, and cross‐headgroup redistribution of n‐3 PUFAs and arachidonic acid, defining a ...
Liyao Huang   +5 more
wiley   +1 more source

Pharmacological treatment strategies to manage precipitated withdrawal following the administration of buprenorphine in opioid use disorder: A systematic review

open access: yesAddiction, Volume 121, Issue 5, Page 1083-1099, May 2026.
Abstract Background and aims There has been limited evidence synthesis examining the treatment of buprenorphine precipitated opioid withdrawal (BPOW). We aimed to conduct the first systematic review to assess the clinical utility of any pharmacological intervention in the management of BPOW.
Emmert Roberts, Nicola Kalk, John Strang
wiley   +1 more source

Survey describing the perspectives and practices of Australian veterinarians to pain management in horses

open access: yesAustralian Veterinary Journal, Volume 104, Issue 5, Page 287-297, May 2026.
Objective To describe Australian practices and attitudes regarding equine analgesia. Study Design Cross‐sectional anonymous, voluntary survey of Australian veterinarians treating equine patients. Methods Australian veterinarians in equine or mixed practices completed a six‐section, 60‐question survey between November 2019 to August 2020.
A Whitelock   +8 more
wiley   +1 more source

Opioids in breast cancer: Between analgesia and modulation of tumour progression

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 9, Page 1727-1746, May 2026.
Preclinical investigations consistently demonstrate that activation of μ‐opioid receptors and δ‐opioid receptors promote proliferation, migration, angiogenesis, epithelial‐mesenchymal transition, acquisition of cancer stem cell phenotypes, and chemoresistance.
Marianna Ciwun   +2 more
wiley   +1 more source

A Scoping Review of Non‐Opioid Therapeutics for Opioid Withdrawal: Translational Relevance to Neonatal Opioid Withdrawal Syndrome (NOWS) Research

open access: yesClinical and Translational Science, Volume 19, Issue 5, May 2026.
ABSTRACT In the wake of the ongoing opioid epidemic, the incidence of neonatal opioid withdrawal syndrome (NOWS) has surged. While the short‐term effects of NOWS are well‐characterized, long‐term physiological and molecular consequences remain unclear.
Sara L. Mills‐Huffnagle   +4 more
wiley   +1 more source

Aetiological relevance of haematological, biochemical and endocrine parameters on equine odontoclastic tooth resorption and hypercementosis (EOTRH)

open access: yesEquine Veterinary Journal, Volume 58, Issue 3, Page 699-708, May 2026.
Abstract Background The dental syndrome EOTRH is a painful, progressive dental disease with an unknown aetiology. The often painful nature of EOTRH emphasises the need for a better knowledge of the underlying pathogenic mechanism and risk factors. A comparative analysis of haematological, biochemical and endocrine values in EOTRH‐affected and non ...
Melusine Tretow   +2 more
wiley   +1 more source

The Buprenorphine Paradox: How Buprenorphine Triggers and Resolves Opioid Withdrawal. [PDF]

open access: yesAddict Biol
Haghdoost M   +6 more
europepmc   +1 more source

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