Results 151 to 160 of about 33,193 (249)

Electroacupuncture decreases Netrin-1-induced myelinated afferent fiber sprouting and neuropathic pain through μ-opioid receptors

Journal of Pain Research, 2019
Hong-Ping Li,1 Wen Su,2 Yang Shu,3 Xiao-Cui Yuan,1 Li-Xue Lin,1 Teng-Fei Hou,1 Hong-Chun Xiang,1 He Zhu,1 Xue-Fei Hu,1 Li Pan,1 Jing-Nan Wu,1 Xian-Fang Meng,1 Hui-Lin Pan,4 Cai-Hua Wu,1,2 Man Li11Department of Neurobiology, School of Basic Medicine ...
Li HP, Su W, Shu Y, Yuan XC, Lin LX, Hou TF, Xiang HC, Zhu H, Hu XF, Pan L, Wu JN, Meng XF, Pan HL, Wu CH, Li M   +14 more
doaj  

Mechanisms of Mu-Opioid Receptors Regulation

NAUKA MOLODYKH (Eruditio Juvenium)
INTRODUCTION: Opioid receptors are key targets for the relief of acute and chronic pain. Unfortunately, the therapeutic effect on these receptors is associated with significant disadvantages, including dependence, tolerance, and the occurrence of side and undesirable effects.
Olga V. Latyshko, Aleksey A. Galkin
openaire   +1 more source

Current Scenario of Pharmaceutical Waste Management in Chattogram District, Southern Bangladesh: A Comprehensive Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Objective Chattogram, a major economic hub with an expanding population, requires additional healthcare facilities. This study identifies current pharmaceutical waste management practices throughout the district and assesses their impact on public health in both urban and rural settings.
Mohammed Abu Sayeed, Mohammed Abdullah Jainul, Md. Jakaria, Mohammad Injamul Hoq, Md. Mayin Uddin Hasan, Mohammed Sailim Ullah   +5 more
wiley   +1 more source

Naldemedine: A New Option for OIBD

Journal of Pain Research, 2020
Flaminia Coluzzi,1 Maria Sole Scerpa,1 Joseph Pergolizzi2 1Department of Medical and Surgical Sciences and Biotechnologies, Sapienza University of Rome, Polo Pontino, Latina, Italy; 2NEMA Research Inc., Naples, FL, USACorrespondence: Flaminia ...
Coluzzi F, Scerpa MS, Pergolizzi J
doaj  

Chronic Pain: Epidemiology, Pathophysiology, and Clinical Management

MedComm, Volume 7, Issue 5, May 2026.
The multidimensional nature of chronic pain is illustrated through four interconnected domains. (Left) Epidemiology and Global Burden: Chronic pain affects approximately one in five individuals globally, contributing to a rising trend in disability‐adjusted life years (YLDs) and a significant socioeconomic impact.
Zhihao Shang, Zijiao Tian, Zhaoquan Wang, Zerui Yang, Ziyao Wang, Zikang Wang, Ziqing Wang, Xingyuan He, Yu Yan, Yuanfeng Gong, Siyuan Xu, Xinyi Li, Guihua Tian   +12 more
wiley   +1 more source

Opioid Receptors Gene Polymorphism and Heroin Dependence in Iran

Basic and Clinical Neuroscience, 2018
Introduction: Genes often have multiple polymorphisms that interact with each other and the environment in different individuals. Variability in the opioid receptors can influence opiate withdrawal and dependence.
Sara Soleimani Asl, Amir Roointan, Hugo Bergen, Shayan Amiri, Parastoo Mardani, Niloufar Ashtari, Ronak Shabani, Mehdi Mehdizadeh   +7 more
doaj  

Cardiopulmonary arrest following extradural analgesia and suspected secondary sympathetic blockade in a critically ill dog

Veterinary Record Case Reports, Volume 14, Issue 2, May 2026.
Abstract An 8‐year‐old, male, entire Cocker Spaniel presented to the Queen Mother Hospital for Animals for treatment of an iatrogenic septic uroabdomen secondary to traumatic urinary catheterisation. After initial stabilisation, it underwent diagnostic imaging and definitive surgical correction comprising a cystotomy and bladder reconstruction.
Joe Simon, Manuel Enrique Herrera‐Linares, Hannah Louise Matson, Cristina Bianchi   +3 more
wiley   +1 more source

Management of suspected opioid‐induced hyperalgesia in a dog

Veterinary Record Case Reports, Volume 14, Issue 2, May 2026.
Abstract Opioid‐induced hyperalgesia is a recognised phenomenon in people, but few cases are described in veterinary patients. This case reports a dog with suspected opioid‐induced hyperalgesia after a stick injury to the mouth and neck, and subsequent surgical exploration of the ventral neck and abscess debridement.
Robin Stallard, Daniel Lomas, Julia Deutsch   +2 more
wiley   +1 more source

Risks of Serious Adverse Events Associated With Non‐Steroidal Anti‐Inflammatory Drugs in Orthopaedic Surgery. A Systematic Review With Meta‐Analysis and Trial Sequential Analysis

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 5, May 2026.
ABSTRACT Background Non‐steroidal anti‐inflammatory drugs (NSAIDs) are recommended for perioperative analgesic treatment. However, NSAID treatment may be associated with increased risk of adverse events. We investigated the risks of serious adverse events with perioperative NSAID treatment in patients undergoing orthopaedic surgery.
Shaheer Bukhari, Morten F. Leth, Christina C. W. Laursen, Mia E. Larsen, Anders S. Tornøe, Nikolaj K. Schou, Marie Glad, Amanda de la Fuente, Janus C. Jakobsen, Mathias Maagard, Ole Mathiesen   +10 more
wiley   +1 more source

Long‐Acting Naltrexone Restores Network Connectivity in Subjects With Comorbid Cannabis and Opioid Use Disorder

Addiction Biology, Volume 31, Issue 5, May 2026.
This study describes functional connectivity (FC) in subjects with opioid use disorder (OUD‐only), OUD+CanUD (cannabis use disorder), OUD+AUD (alcohol use disorder), and OUD+CocUD (cocaine use disorder) before and after naltrexone (NTX). All groups displayed hyper connectivity at baseline; however, on‐NTX, OUD+CanUD and OUD+AUD showed a decrease in ...
Lindsey M. Brier, Daniel D. Langleben, Corinde E. Wiers, Zhenhao Shi   +3 more
wiley   +1 more source