Results 51 to 60 of about 2,381,066 (350)

Oxytocin signal contributes to the adaptative growth of islets during gestation

Endocrine Connections, 2021
Background: Increased insulin production and secretion by pancreatic β-cells are important for ensuring the high insulin demand during gestation . However, the underlying mechanism of β-cell adaptation during gestation or gestational diabetes mellitus ...
Ping Gu, Yuege Lin, Qi Wan, Dongming Su, Qun Shu   +4 more
doaj   +1 more source

Effect of oleic acid supplementation on prostaglandin production in maternal endometrial and fetal allantochorion cells isolated from late gestation ewes [PDF]

, 2015
Elevated circulating non-esterified fatty acids including oleic acid (OA) are associated with many pregnancy related complications. Prostaglandins (PGs) play crucial roles during parturition.
Aardema, Alves, Arsic, Asselin, Carluccio, Catov, Challis, Chen, Cheng, Cheng, Cheng, Cheng, Cherny, Chu, Crane, D.C. Wathes, D.R.E. Abayasekara, Flynn, Goncalves, Guillou, Herath, Jabbour, Karsch, Kim, Klein, Lamont, Lee, Leung, Lewis, Lunn, M. Elmes, Nielsen, Noble, Poyser, Reddy, Rimoldi, Robinson, S. Kirkup, Sharp, Smith, Smith, Thorburn, Villa, Wang, Wathes, Wendell, Whittle, Witkin, Z. Cheng, Zhang   +49 more
core   +2 more sources

Pyrazolsulfonamide Agonists of Oxytocin Receptor [PDF]

ACS Medicinal Chemistry Letters, 2014
Title: Pyrazolsulfonamide Agonists of Oxytocin Receptor Patent/Patent Application Number: WO 2014/111356 A1 Publication date: July 24, 2014 Priority Application: EP 2013-151632 Priority date: January 17, 2013 Inventors: Bissantz, C.; Grundschober, C.; Nettekoven, M.; Plancher, J.-M.; Vifian, W. Assignee Company: Hoffmann-La Roche, Inc.
openaire   +2 more sources

Complementary Role of Oxytocin and Vasopressin in Cardiovascular Regulation

International Journal of Molecular Sciences, 2021
The neurons secreting oxytocin (OXY) and vasopressin (AVP) are located mainly in the supraoptic, paraventricular, and suprachiasmatic nucleus of the brain.
E. Szczepańska-Sadowska, A. Wsół, A. Cudnoch-Jędrzejewska, T. Żera   +3 more
semanticscholar   +1 more source

Carbachol increases intracellular free calcium concentrations in human granulosa-lutein cells [PDF]

, 1992
We investigated whether the stimulation of human granulosa-lutein cells with muscarinic and nicotinic receptor agonists can cause increases in intracellular free calcium (Ca2+), using Fura-2 microfluorimetry.
Föhr, K. J., Gratzl, Manfred, Mayerhofer, Artur, Sterzik, K.   +3 more
core   +1 more source

Dual Oxytocin Signals in Striatal Astrocytes

Biomolecules
The ability of the neuropeptide oxytocin to affect glial cell function is receiving increasing attention. We previously reported that oxytocin at a low nanomolar concentration could inhibit both astrocytic Ca2+ signals and glutamate release.
Elisa Farsetti, Sarah Amato, Monica Averna, Diego Guidolin, Marco Pedrazzi, Guido Maura, Luigi Francesco Agnati, Chiara Cervetto, Manuela Marcoli   +8 more
doaj   +1 more source

New Insights into Atonic Postpartum Hemorrhage: Animal Model Construction Based on Placental Nanodelivery Systems

Advanced Healthcare Materials, EarlyView.
This study develops a placenta‐targeted nanodelivery system co‐loading HMGB1 protein and the NLRP3 agonist nigericin to establish an animal model of atonic postpartum hemorrhage. The model accurately recapitulates clinical phenotypes, including prolonged labor and uterine contractility dysfunction, while revealing inflammatory activation in placental ...
Jiangxue Qu, Ruiqi Wu, Hai Jiang, Lian Chen, Yingying Tian, Shuai Zeng, Tongmin Liu, Cheng Zhao, Huifeng Shi, Xiaolong Liang, Yangyu Zhao   +10 more
wiley   +1 more source

Endocrinologic Control of Men's Sexual Desire and Arousal/Erection [PDF]

, 2016
Several hormones and neurotransmitters orchestrate men's sexual response, including the appetitive (sexual desire) and consummative (arousal and penile erection) phases.
Aversa, Antonio, Burnett, Arthur L., Corona, Giovanni, Isidori, Andrea, Maggi, Mario   +4 more
core   +1 more source

Multiomics Analyses Reveal an Essential Role of Tryptophan in Treatment of csDMARDs in Rheumatoid Arthritis

Advanced Science, EarlyView.
Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian, Jing Zhu, Jianhong Wu, Yan Zhang, Jianghua Chen, Huan Wang, Hengyan Liu, Ke Xu, Jiaxin Huang, Xiaoting Zhu, Yuanli Wei, Shilin Li, Tingting Wang, Xuan Huang, Qinghua Zou, Jie Zhang, Jiang Su, Xinming Du, Yaping Lu, Tianci Zhou, Yingtong Zhou, Minglong Tang, Bin Li, Xue Zhou, Qihao Wei, Qiulong Yan, Fanxin Zeng   +26 more
wiley   +1 more source

Oxytocin decreases colonic motility of cold water stressed rats via oxytocin receptors.

World Journal of Gastroenterology, 2014
AIM To investigate whether cold water intake into the stomach affects colonic motility and the involvement of the oxytocin-oxytocin receptor pathway in rats. METHODS Female Sprague Dawley rats were used and some of them were ovariectomized.
X. Yang, Tao-Fang Xi, Yuxian Li, Haihong Wang, Ying Qin, Jie-Ping Zhang, Wen-Ting Cai, Mengting Huang, Ji-Qiao Shen, Xiaoliang Fan, Xuan-Zheng Shi, D. Xie   +11 more
semanticscholar   +1 more source