Results 131 to 140 of about 21,293 (242)

Multivalent antibody‐based conjugates as new tools for tailored modulation of G protein–coupled receptors

British Journal of Pharmacology, Volume 183, Issue 16, Page 4512-4531, August 2026.
The G protein–coupled receptor (GPCR) superfamily consists of the most common targets of approved drugs. Targeting GPCRs offers appealing avenues for therapeutic development. Antibodies and their fragments, such as single‐domain antibodies (VHHs or nanobodies), have emerged as useful alternatives to small molecule pharmacophores as building blocks in ...
Shivani Sachdev, Ross W. Cheloha
wiley   +1 more source

Pseudohypoparathyroidism in a Chinese girl: A case report. [PDF]

J Int Med Res
Zhao XM, Yang JR, Yin H, Yang CQ, Song Y.   +4 more
europepmc   +1 more source

Vitamin D Supplementation to Prevent Post‐Thyroidectomy Hypocalcemia

Clinical Endocrinology, Volume 105, Issue 2, Page 259-266, August 2026.
ABSTRACT Objective Hypocalcemia is the most common complication following thyroidectomy. Previous studies yielded inconsistent results on whether vitamin D3 prevents postoperative hypocalcemia and were conducted in non‐European countries with different dietary habits and baseline vitamin D levels.
Jeresa I. A. Willems, Daan J. L. van Twist, Kristy M. Pickwell, Patrick L. H. van Battum, Rutgert Bianchi, Annette M. Pijnenburg, James van Bastelaar, Marco Medici, Robin P. Peeters, Roderick F.A. Tummers‐de Lind van Wijngaarden   +9 more
wiley   +1 more source

A case series of hypercalcemia associated with pembrolizumab therapy: evidence for a calcitriol-mediated mechanism. [PDF]

JCEM Case Rep
Belcher V, Barghouthi N, Hadique S, Woomer H, Wong Z, Haider A.   +5 more
europepmc   +1 more source

Does the Combination of Abdominal Obesity and Vitamin D Deficiency Increase the Risk of Death in Individuals Aged 50 or Older? Evidence From the ELSA Study

Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 6607-6617, August 2026.
ABSTRACT Aims Despite the known association between abdominal obesity (AO) and vitamin D deficiency, it remains unclear whether this combination is associated with higher mortality risk. We investigated whether the coexistence of AO and vitamin D deficiency elevates the risk of death.
Joyce da Silva Milliati, Thaís Barros Pereira da Silva, Roberta de Oliveira Máximo, Mariane Marques Luiz, Sara Souza Lima, Andrew Steptoe, Cesar de Oliveira, Tiago da Silva Alexandre   +7 more
wiley   +1 more source

Impact of Clinoptilolite and Anionic Salts on Calcium Homeostasis, Parathyroid Hormone, and Related Metabolic Parameters in Periparturient Dairy Cows. [PDF]

Vet Sci
Huang P, Su X, Guo Y, Ma C, Cao J.
europepmc   +1 more source

Acute GIP and GLP‐1 Administration Exerts Differential Metabolic Effects in Totally Pancreatectomised Individuals

Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 7280-7290, August 2026.
ABSTRACT Aims While being recognised for stimulating pancreatic insulin secretion, GIP and GLP‐1 exert various extrapancreatic effects relevant in the context of incretin‐based therapies. Here, we evaluated the extrapancreatic effects of GIP and GLP‐1, separately and combined, on postprandial physiology in totally pancreatectomised individuals ...
Liva S. L. Krogh, Maja B. Hansen, Natasha C. Bergmann, Carsten P. Hansen, Bolette Hartmann, Jens J. Holst, Filip K. Knop, Asger B. Lund, Lærke S. Gasbjerg   +8 more
wiley   +1 more source

Pheochromocytoma and primary hyperparathyroidism: a very rare association in a neurofibromatosis type 1 patient unmasked by Takotsubo syndrome. [PDF]

Endocrinol Diabetes Metab Case Rep
Faria N, Lopes V, Pereira T, Azevedo O, Lourenço A, Lages AS, Machado CM.   +6 more
europepmc   +1 more source

Primary cardiac T‐cell rich large B‐cell lymphoma causing aortic stenosis with metastasis in a Warmblood

Equine Veterinary Education, Volume 38, Issue 8, Page e488-e495, August 2026.
Summary An 18‐year‐old Warmblood mare was presented to the Royal Veterinary College Equine Referral Hospital for investigation of progressive periocular and facial swelling, weight loss and tachycardia. Physical examination additionally identified bilateral pansystolic (grade 5/6 basilar left‐sided, 2/6 right‐sided), cardiac murmurs, submandibular ...
S. E. Talbot, F. Z. X. Lean, H. M. Martineau, B. Dunkel, J. Reed   +4 more
wiley   +1 more source

Iron Overload: Pathophysiology, Diagnosis and Monitoring

International Journal of Laboratory Hematology, Volume 48, Issue 4, Page 747-756, August 2026.
ABSTRACT Iron overload is associated with significant health risks, underscoring the importance of understanding its pathophysiology as well as establishing accurate diagnostic and monitoring methods. Chronic iron overload is associated with either genetic disorders characterized by excessive iron accumulation (hereditary hemochromatosis), or is ...
Elena Chatzikalil, Polyxeni Delaporta, Konstantinos Bistas, Antonis Kattamis   +3 more
wiley   +1 more source