The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Multiple evolutionary routes to immune diversification across animals. [PDF]
Taguchi M +2 more
europepmc +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Extracellular pneumolysin enhances the activation of cytosolic pattern-recognition receptor NOD2 through its pore-forming activity. [PDF]
Domon H +4 more
europepmc +1 more source
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
PGPR-Mediated Plant Immunity: From Microbial Recognition to Epigenetic Priming. [PDF]
Unal D +4 more
europepmc +1 more source
Unveiling the sensing potential of innate lymphoid cells. [PDF]
Castillo-González R +5 more
europepmc +1 more source
Insect immune systems: same same but different but still same. [PDF]
Cardoso-Jaime V +3 more
europepmc +1 more source
Molecular recognition in plant root endosymbiosis. [PDF]
Fougner-Økland T, Spezzati M, Parys K.
europepmc +1 more source
GrassSV - hybrid method to detect structural variants in high throughput DNA-seq data. [PDF]
Witczak D +9 more
europepmc +1 more source

