Results 151 to 160 of about 4,265,108 (334)

NF9 peptide specific cytotoxic T lymphocyte clone cross react to Y453F mutation of SARS-CoV-2 virus spike protein

Immunological Medicine
The recognition by cytotoxic T cells (CTLs) is essential for the clearance of SARS-CoV-2 virus-infected cells. Several viral proteins have been described to be recognized by CTLs. Among them, the spike (S) protein is one of the immunogenic proteins.
Aiko Murai, Terufumi Kubo, Takayuki Ohkuri, Junko Yanagawa, Yuki Yajima, Akemi Kosaka, Dongliang Li, Toshihiro Nagato, Kenji Murata, Takayuki Kanaseki, Tomohide Tsukahara, Takeshi Nagasaki, Yoshihiko Hirohashi, Hiroya Kobayashi, Toshihiko Torigoe   +14 more
doaj   +1 more source

Signature motif-guided identification of receptors for peptide hormones essential for root meristem growth

Cell Research, 2016
Wen Song, Li Liu, Jizong Wang, Zhen Wu, Heqiao Zhang, Jiao Tang, G. Lin, Yichuan Wang, X. Wen, Wenyang Li, Zhifu Han, Hongwei Guo, J. Chai   +12 more
semanticscholar   +1 more source

A Smart Bio‐Battery Facilitates Diabetic Bone Defect Repair Via Inducing Macrophage Reprogramming and Synergistically Modulating Bone Remodeling Coupling

Advanced Functional Materials, EarlyView.
This research presents a novel implantable bio‐battery, GF‐OsG, tailored for diabetic bone repair. GF‐OsG generates microcurrents in high‐glucose conditions to enhance vascularization, shift macrophages to the M2 phenotype, and regulate immune responses.
Nanning Lv, Haifu Sun, Wenxiang Tang, Yonggang Li, Zhonglai Qian, Lihui Hong, Chong Chen, Hongye Li, Jiaxiang Bai, Yusen Qiao, Mingming Liu   +10 more
wiley   +1 more source

The E3 ubiquitin ligase MARCH1 mediates downregulation of plasma membrane GABAB receptors under ischemic conditions by inhibiting fast receptor recycling

Scientific Reports
GABAB receptors mediate prolonged inhibition in the brain and are important for keeping neuronal excitation and inhibition in a healthy balance. However, under excitotoxic/ischemic conditions, GABAB receptors are downregulated by dysregulated endocytic ...
Musadiq A. Bhat, Mohammad Hleihil, Irene Mondéjar, Thomas Grampp, Dietmar Benke   +4 more
doaj   +1 more source

New development in studies of formyl‐peptide receptors: critical roles in host defense

Journal of Leukocyte Biology, 2016
Liangzhu Li, Keqiang Chen, Yi Xiang, T. Yoshimura, S. Su, Jianwei Zhu, X. Bian, Ji Ming Wang   +7 more
semanticscholar   +1 more source

Programmable DNA‐Peptide Hybrid Nanostructures for Potent Neutralization of Multiple Influenza a Virus Subtypes

Advanced Functional Materials, EarlyView.
A multivalent antiviral platform based on honeycomb‐shaped DNA nanostructures (HC–Urumin) is developed to enhance the potency and breadth of the host defense peptide Urumin. Through spatially patterned trimeric presentation, HC–Urumin disrupts influenza A virus entry, improves cell viability, and reduces disease severity in vivo‐offering a modular and ...
Saurabh Umrao, Abhisek Dwivedy, Payton L. Haak, Dhanush Gandavadi, Laurie A. Rund, Chi Chen, Vineetha Mareddy, Lifeng Zhou, Jinwei Duan, Ying Fang, Andrew J. Steelman, Xing Wang   +11 more
wiley   +1 more source

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors.

Cell, 1998
Xu Luo, I. Budihardjo, Hua Zou, C. Slaughter, Xiaodong Wang   +4 more
semanticscholar   +1 more source

Laser‐Based Sculpturing of Embedded Ultrathin Metal‐Oxide Nanopores for Enhanced Biomolecular Sensing

Advanced Functional Materials, EarlyView.
Controlled laser‐drilling of embedded HfO2 membranes creates three layer nanopores with Gaussian‐shaped cavities sculptured in the supporting layers. These embedded solid‐state nanopores slow DNA translocation by 12‐fold compared to SiNx pores, enabling high‐resolution, label‐free detection of short DNAs, RNAs, and proteins.
Jostine Joby, Yulia Marom, Guocong Lin, Aleksandra Baron‐Wiechec, Amit Meller   +4 more
wiley   +1 more source

The role of atrial natriuretic peptide (ANP) in chronic liver disease. [PDF]

, 1993
Almeida, Angeli, Arendt, Arendt, Badalamenti, Ballermann, Bendtsen, Bernardi, Bernardi, Beutler, Brenard, Buckalew, Cachofeiro, Cantin, Chinkers, Colantonio, De Wardener, Dussaule, Epstein, Epstein, Field, Firth, Gerbes, Gerbes, Gerbes, Gerbes, Gerbes, Gerbes, Gerbes, Gerbes, Gerbes, Gerbes, Gerbes, Ginés, Ginés, Gutkowska, Heim, Henriksen, Henriksen, Henriksen, Henriksen, Inagami, Jiménez, Klepetko, Kollenda, Kollenda, Kramer, La Villa, Laffi, Lang, Lang, Larose, Lenz, López, Maack, Maher, Miyase, Morali, Moreau, Morgan, Naccarato, Nair, Needleman, Panos, Panos, Panos, Pilz, Rashed, Rector, Salerno, Salerno, Schrier, Tesar, Tesar, Trevisani, Tulassay, Uemura, Vinel, Vollmar, Warner, Wilcox, Withrington, Witthaut   +82 more
core   +1 more source

Oral Dosed Organo‐Silica Nanoparticles Restore Glucose Homeostasis and β‐Cell Function in Diabetes Rats

Advanced Functional Materials, EarlyView.
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu, Mingli Wei, Che Bian, Xiaoshuang Bi, Yaxin Deng, Peifu Xiao, Jiansong Zhao, Yuying Wang, Haibing He, Jingxin Gou, Tian Yin, Xing Tang, Li Yang, Hongbo Zhang, Yu Zhang   +14 more
wiley   +1 more source