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Biological Chemistry, 2016
AbstractThis paper is divided into two sections: the first contains the essential elements of the opening lecture presented by Pr. Regoli to the 2015 International Kinin Symposium in S. Paulo, Brazil on June 28th and the second is the celebration of Dr. Regoli’s 60 years of research on vasoactive peptides.
Domenico, Regoli, Fernand, Gobeil
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AbstractThis paper is divided into two sections: the first contains the essential elements of the opening lecture presented by Pr. Regoli to the 2015 International Kinin Symposium in S. Paulo, Brazil on June 28th and the second is the celebration of Dr. Regoli’s 60 years of research on vasoactive peptides.
Domenico, Regoli, Fernand, Gobeil
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Peptide‐Based Carbohydrate Receptors
Chemistry – A European Journal, 2014AbstractA broad spectrum of physiological processes is mediated by highly specific noncovalent interactions of carbohydrates and proteins. In a recent communication we identified several cyclic hexapeptides in a dynamic combinatorial library that interact selectively with carbohydrates with high binding constants in water.
Melanie, Rauschenberg +3 more
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Non-peptide ligands for peptide receptors
Trends in Pharmacological Sciences, 1989Considerable progress has been made in synthesizing peptide analogs with improved stability for probing function of peptide-receptor systems. However, since peptide ligands are usually unsuitable for development as potent orally active long-duration therapeutic agents, considerable research effort is being directed to the development of non-peptidal ...
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Peptide Receptors on Astrocytes
Frontiers in Neuroendocrinology, 1998In recent years, it has become apparent that astrocytes (at least in vitro) harbor functional receptors to almost all possible neurotransmitters (with the potential noticeable exception of acetylcholine nicotinic receptors). Peptides are no exception, since receptors to all neuropeptides known to be produced in the CNS have been found on cultured ...
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Science, 2002
Many small peptides that serve as important signaling molecules have been identified in animals, and more recently similar molecules have been recognized in plants. Matsubayashi et al. have now identified the likely receptor for a sulfated peptide, phytosulfokine, in carrot cells.
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Many small peptides that serve as important signaling molecules have been identified in animals, and more recently similar molecules have been recognized in plants. Matsubayashi et al. have now identified the likely receptor for a sulfated peptide, phytosulfokine, in carrot cells.
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Pharmacological Reviews, 1998
Based on structural and evolutionary criteria, neuropeptide Y (NPY)b, peptide YY (PYY) and pancreatic polypetide (PP) are closely related polypeptides ([Larhammar, 1996a][1]).
M. C. Michel +8 more
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Based on structural and evolutionary criteria, neuropeptide Y (NPY)b, peptide YY (PYY) and pancreatic polypetide (PP) are closely related polypeptides ([Larhammar, 1996a][1]).
M. C. Michel +8 more
semanticscholar +1 more source
Pharmacological Reviews, 1998
Vasoactive intestinal peptide (VIPb) and pituitary adenylate cyclase-activating polypeptide (PACAP) are members of a superfamily of structurally related peptide hormones that includes glucagon, glucagon-like peptide, secretin, and growth hormone ...
A. Harmar +11 more
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Vasoactive intestinal peptide (VIPb) and pituitary adenylate cyclase-activating polypeptide (PACAP) are members of a superfamily of structurally related peptide hormones that includes glucagon, glucagon-like peptide, secretin, and growth hormone ...
A. Harmar +11 more
semanticscholar +1 more source
1993
Publisher Summary Natriuretic peptides play a central role in the regulation of body fluid and electrolyte balance. Binding experiments and cross-linking and autoradiographic studies have confirmed the existence of receptors on astrocytes. The dissociation between the binding affinity and cGMP responses remains unexplained.
V.T.F. Yeung +2 more
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Publisher Summary Natriuretic peptides play a central role in the regulation of body fluid and electrolyte balance. Binding experiments and cross-linking and autoradiographic studies have confirmed the existence of receptors on astrocytes. The dissociation between the binding affinity and cGMP responses remains unexplained.
V.T.F. Yeung +2 more
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Vasoactive Peptides and Their Receptors
Journal of Vascular Research, 1990Peptides act as vasoconstrictors (for instance angiotensins, vasopressin) or vasodilators (the kinins, the neurokinins), both through direct activation of specific receptors in the vascular smooth muscles or indirectly through the release of other endogenous inhibitors of the vascular tone.
D, Regoli +4 more
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Receptors for Relaxin Family Peptides
Annals of the New York Academy of Sciences, 2005Abstract: Recent studies have identified four receptors that are the physiological targets for relaxin family peptides. All are class I (rhodopsin like) G‐protein‐coupled receptors with LGR7 (RXFP1) and LGR8 (RXFP2) being type C leucine‐rich repeat‐containing receptors, whereas GPCR135 (RXFP3) and GPCR142 (RXFP4) resemble receptors that respond to ...
Bathgate, R. +4 more
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