Results 21 to 30 of about 507,789 (292)

Peptide ligand recognition by G protein-coupled receptors

Frontiers in Pharmacology, 2015
The past few years have seen spectacular progress in the structure determination of G protein-coupled receptors (GPCRs). We now have structural representatives from classes A, B, C, and F.
Brian E Krumm, Reinhard eGrisshammer
doaj   +1 more source

Additional file 1 of Clinical and histopathological analyses of VEGF receptors peptide vaccine in patients with primary glioblastoma - a case series

, 2020
Additional file 1: Figure S1. Other factors in the tumor microenvironment. The expression of PD-1 and PD-L1 (A), nestin (B), and CD 163, CD8, CD4 (C) in the tumors of pre- and post- vaccination.
Yukina Morimoto (6669878), Hideaki Nagashima (2717140), Kazunari Yoshida (178698), Ryo Ueda (86965), Ryota Tamura (2216419), Mizuto Sato (8568858), Ryogo Kikuchi (8568864), Masahiro Toda (8568870), Hikaru Sasaki (825157), Yutaka Kawakami (206073), Shinobu Noji (8568867), Yumiko Oishi (8568861), Tetsuro Hikichi (507151), Kenzo Kosugi (8568855)   +13 more
core   +2 more sources

Involvement of mammalian RF-amide peptides and their receptors in the modulation of nociception in rodents

Frontiers in Endocrinology, 2014
Mammalian RF-amide peptides, which all share a conserved carboxyl-terminal Arg-Phe-NH2 sequence, constitute a family of five groups of neuropeptides that are encoded by five different genes.
Safia eAyachi, Frederic eSimonin
doaj   +1 more source

Evolution of a potential hormone antagonist following gene splicing during primate evolution. [PDF]

PLoS ONE, 2013
Alternative splicing of genes generates novel mRNAs, leading to the evolution of new functional proteins. Cholecystokinin (CCK) induces the release of pancreatic enzymes and the contraction of the gallbladder to promote the digestion of fat and proteins.
Cheng Deng, Aaron J W Hsueh
doaj   +1 more source

A Novel Phage-Library-Selected Peptide Inhibits Human TNF-α Binding to Its Receptors

Molecules, 2014
We report the identification of a new human tumor necrosis factor-alpha (TNF-α) specific peptide selected by competitive panning of a phage library. Competitive elution of phages was obtained using the monoclonal antibody adalimumab, which neutralizes ...
Jlenia Brunetti, Barbara Lelli, Silvia Scali, Chiara Falciani, Luisa Bracci, Alessandro Pini   +5 more
doaj   +1 more source

New Frontiers in Molecular Imaging Using Peptide-Based Radiopharmaceuticals for Prostate Cancer

Frontiers in Chemistry, 2020
The high incidence of prostate cancer (PCa) increases the need for progress in its diagnosis, staging, and precise treatment. The overexpression of tumor-specific receptors for peptides in human cancer cells, such as gastrin-releasing peptide receptor ...
Xin Li, Huawei Cai, Xiaoai Wu, Li Li, Haoxing Wu, Rong Tian   +5 more
doaj   +1 more source

Target-Selective Drug Delivery through Liposomes Labeled with Oligobranched Neurotensin Peptides. [PDF]

, 2011
The structure and the in vitro behavior of liposomes filled with the cytotoxic drug doxorubicin (Doxo) and functionalized on the external surface with a branched moiety containing four copies of the 8-13 neurotensin (NT) peptide is reported.
Lelli B, Brunetti J, TESAURO, DIEGO, Falciani C, ACCARDO, ANTONELLA, MORELLI, GIANCARLO, Pini A, Bracci L   +7 more
core   +2 more sources

Additional file 3 of Clinical and histopathological analyses of VEGF receptors peptide vaccine in patients with primary glioblastoma - a case series

, 2020
Additional file 3 ...
Yukina Morimoto (6669878), Hideaki Nagashima (2717140), Kazunari Yoshida (178698), Ryo Ueda (86965), Ryota Tamura (2216419), Mizuto Sato (8568858), Ryogo Kikuchi (8568864), Masahiro Toda (8568870), Hikaru Sasaki (825157), Yutaka Kawakami (206073), Shinobu Noji (8568867), Yumiko Oishi (8568861), Tetsuro Hikichi (507151), Kenzo Kosugi (8568855)   +13 more
core   +2 more sources

Additional file 2 of Clinical and histopathological analyses of VEGF receptors peptide vaccine in patients with primary glioblastoma - a case series

, 2020
Additional file 2: Table S1.
Yukina Morimoto (6669878), Hideaki Nagashima (2717140), Kazunari Yoshida (178698), Ryo Ueda (86965), Ryota Tamura (2216419), Mizuto Sato (8568858), Ryogo Kikuchi (8568864), Masahiro Toda (8568870), Hikaru Sasaki (825157), Yutaka Kawakami (206073), Shinobu Noji (8568867), Yumiko Oishi (8568861), Tetsuro Hikichi (507151), Kenzo Kosugi (8568855)   +13 more
core   +2 more sources

Transcriptomic Analysis of the Kuruma Prawn Marsupenaeus japonicus Reveals Possible Peripheral Regulation of the Ovary

Frontiers in Endocrinology, 2020
Crustacean reproduction has been hypothesized to be under complex endocrinological regulation by peptide hormones. To further improve our understanding of the mechanisms underlying this complex regulation, knowledge is needed regarding the hormones not ...
Naoaki Tsutsui, Naoaki Tsutsui, Yasuhisa Kobayashi, Yasuhisa Kobayashi, Kouichi Izumikawa, Tatsuya Sakamoto   +5 more
doaj   +1 more source