Results 271 to 280 of about 151,487 (293)

Progesterone antagonists and progesterone receptor modulators: an overview

Steroids, 2003
Since the original description of the structure of the antiprogestin, mifepristone, was published, numerous related compounds have been synthesized which may function as progesterone antagonists (PAs) or progesterone receptor modulators (PRMs). The latter are mixed agonists-antagonists.
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Progesterone receptors regulate gallbladder motility

Journal of Surgical Research, 1988
The increased incidence of gallstones in multiparous women may be related to hormonal effects on the gallbladder and its contractility. The occurrence of estrogen and progesterone receptors were studied in the gallbladders of three groups of female guinea pigs (normals, oophorectomized, and oophorectomized treated with estrogen + progesterone for 14 ...
F S, Hould, G M, Fried, A G, Fazekas, S, Tremblay, W A, Mersereau   +4 more
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Progesterone receptors in breast fibroadenomas

Journal of Steroid Biochemistry, 1979
Abstract Cytosol progesterone receptors (P-R) were measured in breast fibroadenomas from 88 women, and their levels were compared to the tumor epithelial cell density and estradiol receptor levels (E-R). Three groups of fibroadenoma were distinguished: type I with a high epithelial cell density (n= 18), type III (n = 46) with low epithelial cell ...
P M, Martin, F, Kuttenn, H, Serment, P, Mauvais-Jarvis   +3 more
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Progesterone Receptors and Ovulation

2010
The steroid hormone, progesterone, plays a critical role in the regulation of female ovulation. The physiological effects of progesterone are mediated by two nuclear receptor transcription factors, PR-A and PR-B, which are produced from a single gene and upon binding progesterone regulate the expression of specific gene networks in reproductive tissues.
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Progesterone and the progesterone receptor.

The Journal of reproductive medicine, 2001
During the 1990s, extensive research has effectively mapped the progesterone receptor-mediated actions of progesterone and has more recently uncovered nonreceptor-mediated effects--the effect of progesterone on uterine sensitivity to oxytocin, for example, involves direct, nongenomic progesterone action on the uterine oxytocin receptor.
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Progesterone Receptor

2021
Irene Porcari, Mariachiara Bosco, Stefano Uccella   +2 more
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Progesterone receptor antagonists.

Current opinion in investigational drugs (London, England : 2000), 2006
Since the discovery of the progesterone receptor antagonist mifepristone, numerous additional compounds, which display a spectrum of biological actions ranging from full antagonist to those with mixed agonist/antagonist activity, have been synthesized. The latter are referred to as selective progesterone receptor modulators. Long-term administration of
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Progesterone Receptor Antagonists and Selective Progesterone Receptor Modulators (SPRMs)

Seminars in Reproductive Medicine, 2005
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PROGESTERONE RECEPTOR ANTAGONISTS

2008
The present invention relates to progesterone receptor antagonists of general formula I: in which R1 can be a hydrogen atom and R2 a hydroxyl group or R1 and R2 together can be an oxo group.
BAYER SCHERING PHARMA AG, FUHRMANN ULRIKE, SCHMIDT ANJA, CLEVE ARWED, PETROV ORLIN, GARKE GUNNAR, PRUEHS STEFAN, BRUDNY-KLOEPPEL MARGARETE, ROTTMANN ANTJE, HASSELMANN RAINER, SCHULTZE-MOSGAU MARCUS, MOELLER CARSTEN   +11 more
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Progesterone Receptor

2008
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