Results 121 to 130 of about 93,312 (311)
Regulation of renal function by prostaglandin E receptors
, 1998 Regulation of renal function by prostaglandin E receptors. Prostaglandin E2 is the major cyclooxygenase product of arachidonic acid metabolism produced along the nephron.
Breyer, Matthew D. +5 more
core +1 more source
Tackling cancer stemness with nanotechnology in the era of precision medicine
BMEMat, EarlyView.Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo +9 more
wiley +1 more source
An investigation of the neuropharmacological and behavioural effects of fenamate and other NSAIDs. [PDF]
, 2001 Recent evidence has indicated that NSAIDs might have direct effects on CNS tissue in addition to their classical inhibitory action on COX enzymes. This thesis addresses this hypothesis using electrophysiological and behavioural techniques. The effects of
Foxon, Graham Ronald
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EP3 prostaglandin receptors in the median preoptic nucleus are critical for fever responses
, 2007 Fever is a result of the action of prostaglandin E2 (PGE2) on the brain and appears to require EP3 prostaglandin receptors (EP3Rs), but the specific neurons on which PGE2 acts to produce fever have not been definitively established.
Lowell, Bradford B +13 more
core +1 more source
Oocyte–cumulus cell interaction: a key factor in early embryo development
Biological Reviews, EarlyView.ABSTRACT The evaluation of oocyte competence is a fundamental step in achieving successful outcomes following assisted reproduction techniques (ART). At present, however, conventional oocyte maturation assessment is carried out by morphological observation, which is a subjective method that does not consider molecular features.
Marc Torres‐Garrido +2 more
wiley +1 more source
Prostaglandin E2 EP receptors in cardiovascular disease: An update
, 2021 This review article provides an update for the role of prostaglandin E2 receptors (EP1, EP2, EP3 and EP4) in cardiovascular disease. Where possible we have reported citations from the last decade although this was not possible for all of the topics ...
Harding, Pamela, Bryson, Timothy D
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Catheterization and Cardiovascular Interventions, EarlyView.ABSTRACT Background Hybrid stage I palliation (HS1P) has developed as an alternative to the Norwood stage I palliation for neonates with hypoplastic left heart and related left‐sided obstructive lesions. HS1P is currently used in various clinical settings, such as single ventricle palliation, bridge to decision, bridge to biventricular repair, or ...
Johanna Hummel +8 more
wiley +1 more source
, 1998 grantor: University of TorontoParturition in the sheep is preceded by increased levels of prostaglandins (PGs) in intrauterine tissues as well as maternal and fetal plasma, reflecting an important role for PGs in the processes leading to the ...
Gyomorey, Sandor
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Role of SoxE transcription factors in development and disease
Developmental Dynamics, EarlyView.Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley +1 more source
, 2005 Prostaglandin E2 (PGE2), is a major prostanoid produced by the activity of cyclooxygenases (COX) in response to various physiological and pathological stimuli. PGE2 exerts its effects by activating four specific E-type prostanoid receptors (EP1, EP2, EP3
Waschbisch, Anne +6 more
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