Results 141 to 150 of about 93,312 (311)

Beyond Gut Modulation: A Critical Review of the Therapeutic Potential, Safety, and Clinical Prospects of Natural Polysaccharides for IBD

Food Safety and Health, EarlyView.
In this review, we critically summarized the application of natural polysaccharides (NPs) for the treatment of IBD. This approach combines, in a unique way (right), the basic structure–activity relationships of NPs from different origins (left) with their multipronged mode of action, which involves modulation of the gut microbiota and other ...
Felix Danso, A. M. Abd El‐Aty, Kwaku Amoah, Xianghong Ju   +3 more
wiley   +1 more source

Bimatoprost in the treatment of eyelash hypotrichosis

Clinical Ophthalmology, 2010
Simon K LawJules Stein Eye Institute, University of California, Los Angeles, California, USAAbstract: Eyelashes hypotrichosis is a condition indicated by an inadequate amount of eyelashes.
Simon K Law
doaj  

Low‐Concentration Dopamine Potentiates Gastric Motility Through Activation of Dopamine D5 Receptor on Enteric Cholinergic Neurons

Gut Medicine, EarlyView.
ABSTRACT Background Dopamine (DA) exerts complex concentration‐dependent effects on gastrointestinal motility. Although its inhibitory action through D2‐like receptors is well‐established, the mechanisms underlying its excitatory effects remain elusive.
Xiao‐Li Zhang, Tuo Ji, Yue Zhang, Cai‐Feng Zhang, Yun‐Jing Bai, Jin Song   +5 more
wiley   +1 more source

Role of prostaglandins and specific place in therapy of bimatoprost in the treatment of elevated intraocular pressure and ocular hypertension: A closer look at the agonist properties of bimatoprost and the prostamides

Clinical Ophthalmology, 2009
Scott D SmidDiscipline of Pharmacology, School of Medical Sciences, Faculty of Health Sciences, University of Adelaide, Adelaide, SA, AustraliaAbstract: Bimatoprost is the only representative of a novel class of prostaglandin ethanolamide (prostamide ...
Scott D Smid
doaj  

Biased agonism of G protein-coupled receptors as a novel strategy for osteoarthritis therapy

Bone Research
Osteoarthritis (OA) is a prevalent degenerative joint disorder marked by chronic pain, inflammation, and cartilage loss, with current treatments limited to symptom relief.
Xiangbo Meng, Ling Qin, Xinluan Wang
doaj   +1 more source

Efectos renales de los inhibidores selectivos de la ciclooxigenasa-2 (COX-2) en la cirrosis. Estudios "in vivo" en ratas inducidas a cirrosis y estudios "in vitro" en células mesangiales. [PDF]

, 2006
[spa] En la cirrosis descompensada, la síntesis renal de prostaglandinas (PGs), juega un papel clave en el mantenimiento de la función renal. En concreto, las PGs renales contrarrestan la exacerbada actividad vasoconstrictora asociada a la activación de ...
López Parra, Marta
core  

Prostaglandin E and F receptors in the uterus

, 2014
Prostaglandins (PGs) are necessary for normal female reproduction. PGs act via their respective receptors and execute various functions in their target tissues depending on which type of receptor being activated.
Chellakkan Selvanesan Blesson, Lena Sahlin
core  

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

Ibrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

PTGER1 and PTGER2 receptors mediate regulation of progesterone synthesis and type 1 11 beta-hydroxysteroid dehydrogenase activity by prostaglandin E(2) in human granulosa-lutein cells

, 2007
Harris, TE, Lopez Bernal, A, Bernal, AL, Michael, AE, Abayasekara, DR, Abayasekara, DRE, Chandras, C   +6 more
core   +1 more source

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source