International Journal of Cancer, EarlyView.ABSTRACT Aspirin has been used to treat pain and fever for 120 years. Its uses expanded into treating arthritis and prevention of thrombotic events. Its anti‐cancer role emerged with observational studies in the 1980's and subsequent cancer review in those treated with aspirin in cardiovascular trials.
John Burn, D. Timothy Bishop
wiley +1 more source
Prostaglandin E2 modulates contractility of mouse bladder smooth muscle cells. [PDF]
Front PhysiolŠumak R +4 more
europepmc +1 more source
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Objective To compare medical termination of pregnancy (TOP) failure in patients with and without prior bariatric surgery (BS) and to compare outcomes by BS subtype. Methods We performed a retrospective cohort study of medical TOP at a single university teaching center between January 2019 and April 2024.
Shai Ingram +4 more
wiley +1 more source
Unique/Rapid Feedback Mechanisms of PGD<sub>2</sub> and PGE<sub>2</sub> as Local/Short-Lived Autacoids; Implications of Biased Activities by Their Metabolites. [PDF]
BioessaysFujino H, Fukushima K.
europepmc +1 more source
Current status and future perspectives of platelet function-guided precision antiplatelet therapy for patients with cerebral infarction. [PDF]
NeuroprotectionAntiplatelet agents target the cyclooxygenase‐1 (COX‐1)/thromboxane A2 (TXA2) and adenosine diphosphate (ADP)‐P2Y12 (cytochrome P450 2C19 [CYP2C19]‐metabolized) platelet activation pathways, resulting in either drug resistance or over‐inhibition. The individualized therapeutic window balances ischemic risk (triggered by high on‐treatment platelet ...
Zhu G +7 more
europepmc +2 more sources
Postpartum febrile morbidity following vacuum‐assisted birth: A retrospective cohort study
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Objective To evaluate whether vacuum‐assisted birth (VAB) independently increases the risk of postpartum febrile morbidity, identifying a potentially modifiable contributor to maternal infectious morbidity. Methods This retrospective cohort study was conducted at a university‐affiliated tertiary maternity center between 2011 and 2023.
Itamar Gilboa +5 more
wiley +1 more source
Vascular Notch-Related Protein Expression in a Rat Model of Central Venous Catheter-Associated <i>Candida albicans</i> Infection Under Antifungal and Prostaglandin-Pathway Interventions. [PDF]
PathogensBerk Cam H +8 more
europepmc +1 more source
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Objectives An increased risk of postpartum posttraumatic stress disorder (PTSD) has been reported in women who had labor induced. Knowledge of childbirth‐related PTSD in this context remain poorly documented. Our aim was to assess the PTSD prevalence and identify characteristics associated with it after induced vaginal delivery at or near term.
Alizée Froeliger +26 more
wiley +1 more source
G-protein coupled receptor, signal and signal-transduction related transcript mapping in nigral volume and pigmented neurons reveals a potential deficit of nigral feedback signals associated with Parkinson's disease. [PDF]
PLoS OneHaynes JM.
europepmc +1 more source
Building families—Implementing balanced sexual and reproductive health
International Journal of Gynecology &Obstetrics, EarlyView.Abstract One of the main initiatives of the World Health Organization (WHO) is the promotion of Sexual and Reproductive Health (SRH). Sexuality, infertility, and contraception are three interconnected pillars of SRH, each essential for achieving global equity in family planning and family building.
Peter Y. Liu +9 more
wiley +1 more source