The role of prostanoids in the retina and optic nerve in health and disease. [PDF]
Ward E +8 more
europepmc +1 more source
ABSTRACT Objective To evaluate whether estimated fetal weight (EFW) growth velocity (GV), assessed using interval‐specific standards, provides additional prediction beyond standard criteria for identifying adverse outcomes in term foetuses with EFW < 10th centile. Design Retrospective cohort study. Setting Tertiary perinatal centre. Population A cohort
Eva Meler +6 more
wiley +1 more source
A drug repurposing screen reveals dopamine signaling as a candidate therapeutic pathway for PIGA-CDG. [PDF]
Aziz MC, Wilson J, Chow CY.
europepmc +1 more source
Association Characteristics and Potential Mechanisms of Aging, Gut Microbiota, and Hearing Loss
The study found that aging leads to unchanged gut microbiota alpha diversity but an increase in Bacteroidetes and a decrease in Firmicutes at the phylum level, with specific genera, species, and functional pathways co‐associated with aging and hearing loss. Through constructing a microbe‐metabolite network, it revealed the mechanism by which protective
Cheng Cheng +7 more
wiley +1 more source
An environmentally relevant phthalate mixture impairs ovulatory prostaglandin and progesterone receptor pathways in human granulosa cells in vitro. [PDF]
Land KL, Xu H, Akin JW, Hannon PR.
europepmc +1 more source
Safety of Venom Immunotherapy in Pregnancy: A Multicentre Study
Venom immunotherapy (VIT) during pregnancy, when maintenance dose is well tolerated, can be continued. No increased risk of adverse effects to VIT or safety concerns for the pregnancy or the newborns were observed. No decreased efficacy of VIT, in case of re‐stings, was reported.
Matteo Martini +20 more
wiley +1 more source
Acute administration of Manning compound during the spawning period reduces reproductive success in female zebrafish. [PDF]
Rajapaksha D +6 more
europepmc +1 more source
The Antidepressant Vortioxetine Potently Inhibits Cell Growth in Cultured Human Glioblastoma Cells Expressing 5-HT<sub>1B</sub> Serotonin Receptors. [PDF]
Russo V +9 more
europepmc +1 more source
Serotonin Degradation and Lipid Metabolism Regulate Human Tc2 Cell Effector Functions
Human Tc2 cells exhibit a metabolically active phenotype characterized by enhanced glycolysis, mitochondrial respiration, and fatty acid uptake dependent on PPARγ. Alarmins strongly amplify IL‐5 and IL‐13 production in Tc2 cells, supporting a shared immunometabolic program across type 2 lymphocytes.
Sabrina de Souza Ferreira +13 more
wiley +1 more source
In Vivo Effect of a Synthetic Amniotic Fluid on Fetal Lung and Gastrointestinal Tract: A Pre-Clinical Rodent Model. [PDF]
Forde B, Finoti S, Oria M, Peiro JL.
europepmc +1 more source

