Results 191 to 200 of about 31,453,429 (295)

Targeting NF-κB Signaling in Preterm Labor: Molecular Mechanisms and Therapeutic Perspectives. [PDF]

Int J Mol Sci
Marynowski M, Mech D, Mastej A, Masiarz A, Kimber-Trojnar Ż.   +4 more
europepmc   +1 more source

Mechanistic Evaluation of Luteolin in Wound Healing of Diabetic Foot Ulcer via Nrf2 Signaling

Phytotherapy Research, EarlyView.
Proposed mechanism by which Luteolin (LU) promotes diabetic foot ulcer healing. LU attenuates hyperglycemia‐induced oxidative stress and lipid peroxidation, improves endothelial cell viability, and suppresses ferroptosis through Nrf2‐dependent antioxidant signaling, thereby accelerating angiogenesis and wound repair. ABSTRACT Diabetic foot ulcers (DFUs)
Muhammed Yusuf, Ayfer Busra Benkli, Ramiz Yusuf   +2 more
wiley   +1 more source

TRPV4-driven ATP release activates CFTR through ADORA2B and P2RY2 receptors in the airway epithelium. [PDF]

iScience
Genovese M, De Santis M, Giordano A, Marotta P, Galietta LJV.   +4 more
europepmc   +1 more source

Immunomodulatory Properties of Withania somnifera: Regulation of Innate Immune Cells and Clinical Implications

Phytotherapy Research, EarlyView.
ABSTRACT Withania somnifera (L.) Dunal (WS), commonly known as Ashwagandha, is a prominent medicinal herb in Ayurveda, with extensive therapeutic potential attributed to its diverse phytochemical profile. This review critically examines the immunomodulatory properties of WS, focusing on innate immune cell populations, including neutrophils, eosinophils,
Rana Yukta, Sonalika Gupta, Gagandeep Kaur, Partha Sarathi Mondal, Milirani Das, Anagha Ranade, Alok Kumar Srivastava, Sachin Kumar, Manoj Kumar Barthwal, Madhu Dikshit   +9 more
wiley   +1 more source

PGE2-mediated NK cell reprogramming drives acquired immunotherapy resistance in lung adenocarcinoma. [PDF]

J Immunother Cancer
Wang Y, Peng C, Feng S, Wen S, Xu C, Du X, Jiang W, Zou R, Shi Y, Ma Y, Xu Z, Jiang M, Shen B.   +12 more
europepmc   +1 more source

Multitarget Regulatory Mechanisms and Research Advances of Plant‐Derived Bioactive Ingredients in Hypertension Prevention and Management

Phytotherapy Research, EarlyView.
Schematic overview of the multi‐target and multi‐pathway mechanisms of PDBI in the prevention and management of hypertension. ABSTRACT Hypertension remains a major global risk factor for cardiovascular diseases, yet current treatments face challenges such as suboptimal blood pressure control and inadequate organ protection.
Qiqi Deng, Yonglin Zhang, Jing Pan, Jing Luo, Hualin Sun, Chaonian Li, Li Li   +6 more
wiley   +1 more source

An environmentally relevant phthalate mixture impairs ovulatory prostaglandin and progesterone receptor pathways in human granulosa cells in vitro. [PDF]

Environ Int
Land KL, Xu H, Akin JW, Hannon PR.
europepmc   +1 more source

Effect of fenamates on prostaglandin E receptor binding

Biomedicine & Pharmacotherapy, 1989
openaire   +1 more source

Pharmacokinetic and Pharmacodynamic Interactions Between Anti‐Asthma Drugs and Medicinal Plants: A Comprehensive Review

Phytotherapy Research, EarlyView.
ABSTRACT Asthma affects 260–300 million people worldwide. About 20%–35% of patients use medicinal plants with their asthma medication, often without telling their clinicians. Disclosure rates are low; up to 42% of asthma outpatients use herbal products, with no records in their charts.
Emine Kocyigit, Aylin Bülbül, Betul Kocaadam‐Bozkurt, Osman Bozkurt, Duygu Ağagündüz, Raffaele Capasso   +5 more
wiley   +1 more source

Acute administration of Manning compound during the spawning period reduces reproductive success in female zebrafish. [PDF]

Front Endocrinol (Lausanne)
Rajapaksha D, Wadhi T, Spitz M, Segar V, Nipu N, Trudeau VL, Mennigen JA.   +6 more
europepmc   +1 more source