Results 161 to 170 of about 8,556 (198)

The P2X7 receptor in leukemia: pathological mechanisms and therapeutic potential. [PDF]

Purinergic Signal
Xue Y, Peng X, Yan M, Du Y, Cao Y, Zhao R.   +5 more
europepmc   +1 more source

Extracellular Adenosine Contributes to the Hydrogen Peroxide-Induced Calcification of Cultured Tendon Cells. [PDF]

Curr Issues Mol Biol
Sakuma T, Mahasarakham CPN, Lin X, Yoshitake H, Nifuji A, Noda M, Ezura Y.   +6 more
europepmc   +1 more source

Single-Cell Transcriptomic Analysis of Macaque LGN Neurons Reveals Novel Subpopulations. [PDF]

Mol Neurobiol
Sun SH, Renshaw KT, Pezaris JS.
europepmc   +1 more source

Purines and purinergic receptors in primary tumors of the central nervous system. [PDF]

Purinergic Signal
Soares AA, Dos Santos HM, Domann KN, Alves NPR, Böhm BR, Haack CM, Pretto KP, Guimarães ES, Rocha GF, de Paula IR, de Alcântara Guimarães LE, de Ávila Pessoa HC, Rodrigues RD, Dalagnol AMK, da Cunha MLV, de Resende E Silva DT.   +15 more
europepmc   +1 more source

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P1 and P2 purinergic receptor signal transduction in rat type II pneumocytes

Journal of Applied Physiology, 1989
Extracellular ATP is a potent agonist of surfactant phosphatidylcholine (PC) exocytosis from type II pneumocytes in culture. We studied P1 and P2 receptor signal transduction in type II pneumocytes. The EC50 for ATP on PC exocytosis was 10(-6) M, whereas the EC50 for ADP, AMP, adenosine, and the nonmetabolizable ATP analogue alpha,beta-methylene ATP ...
D, Warburton, S, Buckley, L, Cosico
openaire   +2 more sources

Purinergic receptors in microglia: Functional modal shifts of microglia mediated by P2 and P1 receptors

Glia, 2012
AbstractMicroglia are sensitive to environmental changes and are immediately transformed into several phenotypes. For such dynamic “modal shifts”, purinergic receptors have central roles. When microglia sense ATP/ADP leaked from injured cells by P2Y12 receptors, they are transformed into a moving phenotype, showing process extension and migration ...
Schuichi, Koizumi, Keiko, Ohsawa, Kazuhide, Inoue, Shinichi, Kohsaka   +3 more
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Genistein, an Inhibitor of Protein Tyrosine Kinase, Is Also a Competitive Antagonist for P1-Purinergic (Adenosine) Receptor in FRTL-5 Thyroid Cells

Biochemical and Biophysical Research Communications, 1994
Genistein, a potent inhibitor for protein tyrosine kinase, remarkably inhibited the stimulatory action of N6-(L-2-phenylisopropyl)adenosine (PIA), an A1-adenosine receptor agonist, on thyrotropin (TSH)-induced phospholipase C activation in FRTL-5 thyroid cells.
F, Okajima, M, Akbar, M, Abdul Majid, K, Sho, H, Tomura, Y, Kondo   +5 more
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On the purinergic system in rat duodenum : existence of P₁and P₂receptors on the smooth muscle

Archives Internationales de Physiologie et de Biochimie, 1990
In rat duodenum, in vitro, in the presence of atropine and guanethidine, ATP administration caused a tetrodotoxin-insensitive relaxation followed by a rebound contraction. A similar response was obtained also after electrical field stimulation (EFS) of non-adrenergic, non-cholinergic (NANC) nerves.
A, Postorino, R, Serio, F, Mulè
openaire   +2 more sources

Antihypertensive effects of the Vitis vinifera grape skin (ACH09) extract consumption elicited by functional improvement of P1 (A1) and P2 (P2X1) purinergic receptors in diabetic and hypertensive rats

PharmaNutrition, 2019
Abstract Cross-talk between hypertension and diabetes associated with red wine consumption triggering cardioprotective and antihypertensive effects have been well established; nevertheless, the role of isolated total polyphenols from extracts of Vitis vinifera grape skin (ACH09) and the possible correlation with cardiovascular functionality mediated ...
Guilherme Henrique Souza Bomfim, Diego Castro Musial, Regiane Miranda-Ferreira, Sthefani Rodrigues Nascimento, Aron Jurkiewicz, Neide Hyppolito Jurkiewicz, Roberto Soares de Moura   +6 more
openaire   +1 more source