Results 131 to 140 of about 57,506 (257)

Common Hematologic Emergencies—Acute Promyelocytic Leukemia and Microangiopathic Hemolytic Anemias—A Pivotal Role of Clinical Laboratory

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Hematologic emergencies are urgent health conditions which result in significant mortality and morbidity unless timely therapeutic measures are taken. Therapeutic success depends on their timely and accurate recognition by hematology laboratory services.
Ganna Shestakova, Nicolas Ulrich Edgar, Anton V. Rets   +2 more
wiley   +1 more source

The retinoic acid-related orphan receptors (RORs) signaling axis in skeletal homeostasis: mechanistic insights and chronotherapeutic prospects. [PDF]

Ann Med
Wei L, Yue Q, Yang D, Miao S, Lu M, Zhang Z, Liang X, Zhang X, Zhang Y.   +8 more
europepmc   +1 more source

Contribution of XN‐10 Sysmex Parameters in the Cytological Monitoring of Acute Promyelocytic Leukemia

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Objectives The all‐trans‐retinoic acid (ATRA) treatment used in acute promyelocytic leukemia (APL) has the particularity of inducing differentiation of the leukemia cells. As a result, within the same smear, several stages of cellular differentiation of the granular lineage are present, which can make it difficult to distinguish elements when ...
Lucille De Maria, Logan Baldini, Joy Mouanes Abelin, Corinne Ferrero, Yann Boursier, Yael Berda‐Haddad, Pierre Toulon   +6 more
wiley   +1 more source

All-Trans Retinoic Acid Impacts Early Palatal Shelves Development via the Wnt and TGF-β Signaling Pathways. [PDF]

Biomedicines
Ma Y, Wang B, Gao S, Song T.
europepmc   +1 more source

Differential peritoneal resident macrophage depletion and omental milky spot disruption after high versus low clodronate‐loaded liposome dose treatment

Immunology &Cell Biology, EarlyView.
In this study, we found that intraperitoneal injection of a high (standard) clodronate‐loaded liposome dose induced persistent peritoneal macrophage depletion, paralleled by marked inflammation and compromised omental integrity. Conversely, low liposome dose caused transient macrophage depletion, low inflammation and no omental alterations, ensuring ...
Margarita Ferriz, Natalia Álvarez‐Ladrón, Alejandra Gutiérrez‐González, Marta H. Fernández‐Sesma, Ana Starešinčić, Carlos Ardavín   +5 more
wiley   +1 more source

Modifications of Cytochrome <i>c</i> by Retinoic Acid Play a Crucial Role in Mitochondrial Dysfunction of Triple-Positive Human Breast Cancer Cells: Raman Spectroscopy and Imaging Study. [PDF]

ACS Omega
Abramczyk H, Kopeć M, Surmacki J.
europepmc   +1 more source

Neurotrophic extracellular matrix proteins promote neuronal and iPSC astrocyte progenitor cell‐ and nano‐scale process extension for neural repair applications

Journal of Anatomy, Volume 246, Issue 4, Page 585-601, April 2025.
The extracellular matrix plays a critical role in modulating cell behaviour in the central nervous system influencing neural cell morphology and growth. However, a better understanding of the impact of individual matrix proteins on both neurons and astrocytes is critical for advancing the development of matrix‐based neural repair strategies.
Cian O'Connor, Rena E. Mullally, Sarah F. McComish, Julia O'Sullivan, Ian Woods, Ingmar Schoen, Massimiliano Garre, Maeve A. Caldwell, Adrian Dervan, Fergal J. O'Brien   +9 more
wiley   +1 more source

Modulation of axon excitable domains by astrocytes and microglia. [PDF]

Front Cell Neurosci
Garrido JJ.
europepmc   +1 more source

The Evolving Landscape of CHD Genetics: A Contemporary Guide to Genetic Testing and Management

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Congenital heart disease (CHD) is the most common birth defect, affecting an estimated 9.4/1000 infants globally. The genetics of CHD is complex, with most cases thought to have multifactorial aetiology, implicating both genetic and environmental factors.
Bridget R. O'Malley, Gary F. Sholler, Janine Smith, Gillian M. Blue   +3 more
wiley   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth, Zhou Yuxi, Yong Jiawen, Wang Lei, Ruf Sabine, Meyle Joerg   +5 more
wiley   +1 more source