Results 191 to 200 of about 101,003 (237)

Myeloid‐Derived Suppressor Cells in Cancer: Mechanistic Insights and Targeted Therapeutic Innovations

MedComm, Volume 6, Issue 6, June 2025.
This review summarizes the origin and biological characteristics of MDSCs, focusing on their immunological and nonimmunological roles in tumor progression. It also discusses the prognostic value of MDSCs and the latest advancements in clinical trials, highlighting the potential of emerging therapeutic strategies for cancer treatment and drug ...
Tianying Hu, Jianxue Zhai, Zhanda Yang, Jiajia Peng, Chuxuan Wang, Xinyao Liu, Yawen Li, Jiaqi Yao, Fengxi Chen, Haixia Li, Taixue An, Zongcai Liu, Haifang Wang   +12 more
wiley   +1 more source

Feedback regulation of retinaldehyde reductase DHRS3, a critical determinant of retinoic acid homeostasis. [PDF]

FEBS Lett
Varshosaz P, O'Connor C, Moise AR.
europepmc   +1 more source

Characteristic, Regulation and Targeting Strategies of Cancer Stem Cells and Their Niche in Digestive System Tumors

MedComm – Oncology, Volume 4, Issue 2, June 2025.
Cancer stem cells, characterized by self‐renewal, differentiation, heterogeneity, plasticity and tumorigenicity, are regulated by intrinsic factors such as signaling pathways, transcription factors, metabolism and noncoding RNAs, as well as environmental cells (including tumor cells, immune cells and stromal cells), environmental factors and distant ...
Zhenzhen Chen, Huanle Qi, Yapeng Xue, Yaqi Zhang, Zhuo Zhang, Shun Xu, Shixin Liao, Xiaoyu Zeng, Jiayi Wu, Xinrui Lv, Qiankun He, Pingping Zhu   +11 more
wiley   +1 more source

FXR Activation Accelerates Early Phase of Osteoblast Differentiation Through COX-2-PGE₂-EP4 Axis in BMP-2-Induced Mouse Mesenchymal Stem Cells. [PDF]

Molecules
Fujimori K, Iguchi Y, Yamashita Y, Gohda K, Teno N.   +4 more
europepmc   +1 more source

Altered synaptic homeostasis: a key factor in the pathophysiology of depression. [PDF]

Cell Biosci
Wang B, He T, Qiu G, Li C, Xue S, Zheng Y, Wang T, Xia Y, Yao L, Yan J, Chen Y.   +10 more
europepmc   +1 more source

Vitamins in the Pathogenesis of Prostate Cancer: Implications for Prevention and Therapeutic Support. [PDF]

Int J Mol Sci
Królikowska K, Kiślak J, Orywal K, Zajkowska M.   +3 more
europepmc   +1 more source

Targeting Pathways in Neuroblastoma: Advances in Treatment Strategies and Clinical Outcomes. [PDF]

Int J Mol Sci
Benchia D, Bîcă OD, Sârbu I, Savu B, Farcaș D, Miron I, Postolache AL, Cojocaru E, Abbo O, Ciongradi CI.   +9 more
europepmc   +1 more source

PRAME is not a frequently expressed antigen in renal cell carcinoma

BJUI Compass, Volume 6, Issue 6, June 2025.
Irvin Yi, Yael Derdikman Ofir, Jacqueline Mann, David Su, Tara Kim, Oscar Perales, Lin Zhang, Adebowale Adeniran, Harriet M. Kluger, David A. Schoenfeld   +9 more
wiley   +1 more source

The potential of retinoic acid receptors as prognostic biomarkers and therapeutic targets in gastric cancer. [PDF]

Front Oncol
Garattini SK, Basile D, De Re V, Brisotto G, Miolo G, Canzonieri V, Aprile G, Corvaja C, Buriolla S, Garattini E, Puglisi F.   +10 more
europepmc   +1 more source

A Single-Center, Blinded, Placebo-Controlled Study Evaluating Cosmetic Efficacy and Safety of a Novel Topical GLPSGLT in Glucagon-Like Peptide-1 Analog-Treated Patients. [PDF]

Aesthet Surg J Open Forum
Semersky A, Pryor S, Barwood-Parent C, Lee M, Copeland K, Few J.   +5 more
europepmc   +1 more source